(Q41502419)

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A disease-causing point mutation in human mitochondrial tRNAMet results in tRNA misfolding leading to defects in translational initiation and elongation

scientific article published on 3 October 2008

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1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

A disease-causing point mutation in human mitochondrial tRNAMet results in tRNA misfolding leading to defects in translational initiation and elongation (English)

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

author name string

Christie N Jones

1

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Christopher I Jones

2

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

William D Graham

3

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Paul F Agris

4

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Linda L Spremulli

5

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Europe PubMed Central

PMC publication ID

1 October 2017

language of work or name

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publication date

3 October 2008

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Europe PubMed Central

PMC publication ID

1 October 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

1 October 2017

283

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Europe PubMed Central

PMC publication ID

1 October 2017

49

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

34445-34456

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2590712/fullTextXML

based on heuristic

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1 reference

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Decreased aminoacylation in pathology-related mutants of mitochondrial tRNATyr is associated with structural perturbations in tRNA architecture.

1 reference

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Pathogenic mechanism of a human mitochondrial tRNAPhe mutation associated with myoclonic epilepsy with ragged red fibers syndrome.

1 reference

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Selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE): quantitative RNA structure analysis at single nucleotide resolution

1 reference

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A fast-acting reagent for accurate analysis of RNA secondary and tertiary structure by SHAPE chemistry

1 reference

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A counterintuitive Mg2+-dependent and modification-assisted functional folding of mitochondrial tRNAs

1 reference

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RNA structure analysis at single nucleotide resolution by selective 2'-hydroxyl acylation and primer extension (SHAPE)

1 reference

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1 reference

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Codon-specific translational defect caused by a wobble modification deficiency in mutant tRNA from a human mitochondrial disease

1 reference

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Interaction of mitochondrial initiation factor 2 with mitochondrial fMet-tRNA.

1 reference

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Impact of disease-related mitochondrial mutations on tRNA structure and function

1 reference

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1 reference

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Human mitochondrial tRNAs in health and disease.

1 reference

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Decreased mitochondrial tRNALys steady-state levels and aminoacylation are associated with the pathogenic G8313A mitochondrial DNA mutation

1 reference

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The pathogenic U3271C human mitochondrial tRNA(Leu(UUR)) mutation disrupts a fragile anticodon stem

1 reference

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In vitro 3'-end endonucleolytic processing defect in a human mitochondrial tRNA(Ser(UCN)) precursor with the U7445C substitution, which causes non-syndromic deafness

1 reference

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Uniform binding of aminoacyl-tRNAs to elongation factor Tu by thermodynamic compensation

1 reference

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10 June 2018

Search for characteristic structural features of mammalian mitochondrial tRNAs.

1 reference

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Structural and functional roles of the N1- and N3-protons of psi at tRNA's position 39

1 reference

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Mammalian mitochondrial methionyl-tRNA transformylase from bovine liver. Purification, characterization, and gene structure.

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1 reference

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A disease-associated G5703A mutation in human mitochondrial DNA causes a conformational change and a marked decrease in steady-state levels of mitochondrial tRNA(Asn).

1 reference

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Structure of an RNA double helix including uracil-uracil base pairs in an internal loop

1 reference

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Higher-order structure of bovine mitochondrial tRNA(SerUGA): chemical modification and computer modeling.

1 reference

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Higher-order structure of bovine mitochondrial tRNA(Phe) lacking the 'conserved' GG and T psi CG sequences as inferred by enzymatic and chemical probing.

1 reference

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Complete sequence of bovine mitochondrial DNA. Conserved features of the mammalian mitochondrial genome

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Mutagenesis of Arg335 in bovine mitochondrial elongation factor Tu and the corresponding residue in the Escherichia coli factor affects interactions with mitochondrial aminoacyl-tRNAs.

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Functional defects of pathogenic human mitochondrial tRNAs related to structural fragility

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1 reference

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1 reference

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based on heuristic

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Mitochondrial tRNA mutations: clinical and functional perturbations

1 reference

https://pubmed.ncbi.nlm.nih.gov/18835817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bovine mitochondrial initiation and elongation factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18835817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of mitochondrial elongation factor Tu with aminoacyl-tRNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18835817

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based on heuristic

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Interaction of mitochondrial elongation factor Tu with aminoacyl-tRNA and elongation factor Ts

1 reference

https://pubmed.ncbi.nlm.nih.gov/18835817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M806992200

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

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