(Q41099892)

26 September 2017

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title

Cdk inhibitors in development and cancer (English)

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26 September 2017

Harper JW

1

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26 September 2017

Elledge SJ

series ordinal

2

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26 September 2017

publication date

1 February 1996

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Current Opinion in Genetics & Development

26 September 2017

published in

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26 September 2017

volume

6

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26 September 2017

issue

1

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26 September 2017

page(s)

56-64

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G1 phase progression: cycling on cue

26 September 2017

cites work

1 reference

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7 January 2021

Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

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7 January 2021

Cell cycle control and cancer

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7 January 2021

Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle

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7 January 2021

Cdk inhibitors: on the threshold of checkpoints and development

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7 January 2021

Inhibitors of mammalian G1 cyclin-dependent kinases

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7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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7 January 2021

p21 is a universal inhibitor of cyclin kinases

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

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7 January 2021

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

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7 January 2021

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

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7 January 2021

p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene

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7 January 2021

Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution

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7 January 2021

Inhibition of cyclin-dependent kinases by p21

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7 January 2021

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

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7 January 2021

p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F.

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7 January 2021

A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen

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7 January 2021

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

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7 January 2021

p21-containing cyclin kinases exist in both active and inactive states

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7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

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7 January 2021

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

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7 January 2021

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

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7 January 2021

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

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7 January 2021

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

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7 January 2021

Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4

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7 January 2021

Germline p16 mutations in familial melanoma

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7 January 2021

Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus

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7 January 2021

Tumor suppression. Lessons in p16 from phylum Falconium

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7 January 2021

Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

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7 January 2021

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

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7 January 2021

Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation

1 reference

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7 January 2021

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

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7 January 2021

Tumour suppressors, kinases and clamps: how p53 regulates the cell cycle in response to DNA damage.

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7 January 2021

A p53-dependent mouse spindle checkpoint

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7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

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7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

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7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

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7 January 2021

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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7 January 2021

Requirement for tyrosine phosphorylation of Cdk4 in Gl arrest induced by ultraviolet irradiation

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7 January 2021

p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

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7 January 2021

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

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7 January 2021

Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD.

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7 January 2021

Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase

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7 January 2021

Ectopic expression of cyclin D1 prevents activation of gene transcription by myogenic basic helix-loop-helix regulators

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7 January 2021

Cyclin D1 provides a link between development and oncogenesis in the retina and breast

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7 January 2021

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

1 reference

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7 January 2021

Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation.

1 reference

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7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

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7 January 2021

10.1016/S0959-437X(96)90011-8

Identifiers

DOI

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26 September 2017

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