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Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
title
Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
main subject
protein design
0 references
author
David P. Lane
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author name string
A Böttger
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
V Böttger
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
A Sparks
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
W L Liu
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
S F Howard
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
language of work or name
English
0 references
publication date
1 November 1997
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
number of pages
10
1 reference
based on heuristic
inferred from page(s)
published in
Current Biology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
volume
7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
issue
11
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
page(s)
860-869
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
cites work
High-frequency developmental abnormalities in p53-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53, the cellular gatekeeper for growth and division
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
mdm2 expression is induced by wild type p53 activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p53-mdm-2 autoregulatory feedback loop
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 promotes the rapid degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 stability by Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular characterization of the hdm2-p53 interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A thioredoxin gene fusion expression system that circumvents inclusion body formation in the E. coli cytoplasm.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tolerance of high levels of wild-type p53 in transformed epithelial cells dependent on auto-regulation by mdm-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MDM2 gene amplification and transcript levels in human sarcomas: relationship to TP53 gene status
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small peptides activate the latent sequence-specific DNA binding function of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Similarities between prokaryotic and eukaryotic cyclic AMP-responsive promoter elements
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0960-9822(06)00374-5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
PubMed publication ID
9382809
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
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