Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q41063629)
Watch
English
Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo.
scientific article
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
title
Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
main subject
protein design
0 references
author
David P. Lane
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author name string
A Böttger
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
V Böttger
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
A Sparks
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
W L Liu
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
S F Howard
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
language of work or name
English
0 references
publication date
1 November 1997
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
number of pages
10
1 reference
based on heuristic
inferred from page(s)
published in
Current Biology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
volume
7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
issue
11
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
page(s)
860-869
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
cites work
High-frequency developmental abnormalities in p53-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53, the cellular gatekeeper for growth and division
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
mdm2 expression is induced by wild type p53 activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p53-mdm-2 autoregulatory feedback loop
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 promotes the rapid degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 stability by Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular characterization of the hdm2-p53 interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A thioredoxin gene fusion expression system that circumvents inclusion body formation in the E. coli cytoplasm.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tolerance of high levels of wild-type p53 in transformed epithelial cells dependent on auto-regulation by mdm-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MDM2 gene amplification and transcript levels in human sarcomas: relationship to TP53 gene status
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small peptides activate the latent sequence-specific DNA binding function of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Similarities between prokaryotic and eukaryotic cyclic AMP-responsive promoter elements
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2806%2900374-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0960-9822(06)00374-5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
PubMed publication ID
9382809
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9382809
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9382809%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
