(Q40928973)

24 September 2017

title

Transforming growth factor-beta responsiveness in DPC4/SMAD4-null cancer cells (English)

1 reference

24 September 2017

Dai JL

1

1 reference

24 September 2017

Schutte M

2

1 reference

24 September 2017

Bansal RK

3

1 reference

24 September 2017

Wilentz RE

4

1 reference

24 September 2017

Sugar AY

5

1 reference

24 September 2017

Kern SE

6

1 reference

24 September 2017

publication date

1 September 1999

1 reference

24 September 2017

published in

Molecular Carcinogenesis

1 reference

24 September 2017

volume

26

1 reference

24 September 2017

issue

1

1 reference

24 September 2017

page(s)

37-43

1 reference

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

24 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Human Smad3 and Smad4 are sequence-specific transcription activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

G1 cell cycle arrest and apoptosis induction by nuclear Smad4/Dpc4: phenotypes reversed by a tumorigenic mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Mad-related genes in the human

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Genetic changes in the transforming growth factor beta (TGF-beta) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Characterization of functional domains within Smad4/DPC4

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Up-regulation of transforming growth factor (TGF)-beta receptors by TGF-beta1 in COLO-357 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Amplification of a gene encoding a p53-associated protein in human sarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Altered transforming growth factor signaling in epithelial cells when ras activation is blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

A synthetic inhibitor of the mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Blockade of TGFbeta3 up-regulation of p27Kip1 and p21Cip1 by expression of RasN17 in epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Increasing complexity of the Ras signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

Activation of the hematopoietic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun N-terminal kinase (JNK) pathway by transforming growth factor beta (TGF-beta)-activated kinase (TAK1), a kinase mediator of TGF beta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2744%28199909%2926%3A1%3C37%3A%3AAID-MC5%3E3.0.CO%3B2-6

10.1002/(SICI)1098-2744(199909)26:1<37::AID-MC5>3.0.CO;2-6

21 January 2018

Identifiers

DOI

1 reference

24 September 2017

1 reference