(Q40922234)

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21 October 2019

title

Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8934573%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

0 references

1

1 reference

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21 October 2019

author name string

R N Germain

series ordinal

2

1 reference

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21 October 2019

language of work or name

English

0 references

publication date

1 November 1996

1 reference

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21 October 2019

1 reference

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21 October 2019

volume

5

1 reference

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21 October 2019

issue

5

1 reference

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21 October 2019

page(s)

461-477

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A human CD4 transgene rescues CD4-CD8+ cells in beta 2-microglobulin-deficient mice.

21 October 2019

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Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.

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7 January 2021

Another view of the selective model of thymocyte selection.

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7 January 2021

A challenge to the instructive model of positive selection

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Mice lacking MHC class II molecules

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7 January 2021

Thymocyte development in major histocompatibility complex-deficient mice: evidence for stochastic commitment to the CD4 and CD8 lineages

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7 January 2021

Thymocyte lineage commitment: is it instructed or stochastic?

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7 January 2021

Disrupted development of thymocytes expressing a transgenic TCR upon CD4 overexpression.

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7 January 2021

Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes.

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T-cell antigen receptor genes and T-cell recognition

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Interaction between CD4 and class II MHC molecules mediates cell adhesion

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7 January 2021

Early T lymphocytes. Differentiation in vivo of adult intrathymic precursor cells

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7 January 2021

T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages

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T cell receptor antagonist peptides induce positive selection

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7 January 2021

Stochastic component to development of class I major histocompatibility complex-specific T cells

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7 January 2021

The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells

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7 January 2021

Specificity and flexibility in thymic selection

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7 January 2021

Early molecular events induced by T cell receptor (TCR) signaling in immature CD4+ CD8+ thymocytes: increased synthesis of TCR-alpha protein is an early response to TCR signaling that compensates for TCR-alpha instability, improves TCR assembly, and

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7 January 2021

Upregulation of surface markers on dying thymocytes

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7 January 2021

Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.

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7 January 2021

Stochastic coreceptor shut-off is restricted to the CD4 lineage maturation pathway

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7 January 2021

Small cortical thymocytes are subject to positive selection

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7 January 2021

Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes

1 reference

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7 January 2021

Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

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7 January 2021

Generation of mature T cell populations in the thymus: CD4 or CD8 down-regulation occurs at different stages of thymocyte differentiation.

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7 January 2021

MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent.

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7 January 2021

Decreased signaling competence as a result of receptor overexpression: overexpression of CD4 reduces its ability to activate p56lck tyrosine kinase and to regulate T-cell antigen receptor expression in immature CD4+CD8+ thymocytes

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7 January 2021

Cell-cell adhesion mediated by CD8 and MHC class I molecules

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7 January 2021

In vitro differentiation and commitment of CD4+ CD8+ thymocytes to the CD4 lineage, without TCR engagement.

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7 January 2021

Negative selection of CD4+ CD8+ thymocytes by T-cell receptor peptide antagonists

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7 January 2021

Evidence for differential intracellular signaling via CD4 and CD8 molecules

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7 January 2021

Selective events in T cell development

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7 January 2021

Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage.

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7 January 2021

Constitutive CD8 expression allows inefficient maturation of CD4+ helper T cells in class II major histocompatibility complex mutant mice

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7 January 2021

Thymic emigration: conveyor belts or lucky dips?

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7 January 2021

Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy

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7 January 2021

Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection.

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7 January 2021

Clonal deletion of immature CD4+8+ thymocytes in suspension culture by extrathymic antigen-presenting cells

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7 January 2021

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

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7 January 2021

Development of mature CD8+ thymocytes: selection rather than instruction?

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7 January 2021

The different roles of MHC class recognition in thymocyte CD4 versus CD8 lineage commitment and positive selection.

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7 January 2021

In vivo and in vitro clonal deletion of double-positive thymocytes

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7 January 2021

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

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7 January 2021

The selection of the α,β heterodimeric T-cell receptor for antigen

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7 January 2021

The T-cell receptor for antigen in T-cell development and repertoire selection

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7 January 2021

The thymus selects the useful, neglects the useless and destroys the harmful

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7 January 2021

TCR activation of ZAP70 is impaired in CD4+CD8+ thymocytes as a consequence of intrathymic interactions that diminish available p56lck

1 reference

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7 January 2021

Inhibition of thymocyte negative selection by T cell receptor antagonist peptides

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7 January 2021

Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.

1 reference

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7 January 2021

Positive selection of CD4-CD8+ T cells in the thymus of normal mice

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7 January 2021

CD8 is required during positive selection of CD4-/CD8+ T cells

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7 January 2021

10.1016/S1074-7613(00)80502-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8934573%20AND%20SRC:MED&resulttype=core&format=json

release_gednumhn5zfltaczjrcr3bplma

21 October 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gednumhn5zfltaczjrcr3bplma

24 November 2022

mapped directly with Wikidata item

1 reference