(Q40671353)

22 September 2017

title

Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway (English)

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22 September 2017

Hiroaki Iwasa

1

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22 September 2017

Jiahuai Han

series ordinal

2

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22 September 2017

Fuyuki Ishikawa

series ordinal

3

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22 September 2017

publication date

1 February 2003

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22 September 2017

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22 September 2017

volume

8

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22 September 2017

issue

2

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22 September 2017

page(s)

131-144

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Extension of life-span by introduction of telomerase into normal human cells

22 September 2017

cites work

1 reference

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Control of replicative life span in human cells: barriers to clonal expansion intermediate between M1 senescence and M2 crisis

21 January 2018

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Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

21 January 2018

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Mammalian MAP kinase signalling cascades

21 January 2018

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Telomere loss: mitotic clock or genetic time bomb?

21 January 2018

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Aging clock: the watchmaker's masterpiece

21 January 2018

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Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants

21 January 2018

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Senescence Induced by Altered Telomere State, Not Telomere Loss

21 January 2018

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Signal transduction from multiple Ras effectors

21 January 2018

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Retinoblastoma gene product activates expression of the human TGF-β2 gene through transcription factor ATF-2

21 January 2018

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Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

21 January 2018

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Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles

21 January 2018

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Selective activation of p38 MAPK cascade and mitotic arrest caused by low level oxidative stress

21 January 2018

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

21 January 2018

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Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

21 January 2018

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Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

21 January 2018

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Atmospheric carbon dioxide concentrations over the past 60 million years

21 January 2018

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MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

21 January 2018

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Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

21 January 2018

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Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

21 January 2018

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

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Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

21 January 2018

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Cellular senescence: mitotic clock or culture shock?

21 January 2018

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Different telomere damage signaling pathways in human and mouse cells

21 January 2018

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Defects in TGF-beta signaling overcome senescence of mouse keratinocytes expressing v-Ha-ras

21 January 2018

1 reference

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Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2443.2003.00620.X

10.1046/J.1365-2443.2003.00620.X

21 January 2018

Identifiers

DOI

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22 September 2017

1 reference