(Q40661246)

22 September 2017

Contributions of cell metabolism and H+ diffusion to the acidic pH of tumors (English)

1 reference

22 September 2017

2

1 reference

22 September 2017

Paul A Schornack

1

1 reference

PMC publication ID

1502399

22 September 2017

language of work or name

1 reference

1 March 2003

1 reference

22 September 2017

1 reference

22 September 2017

5

1 reference

22 September 2017

2

1 reference

22 September 2017

135-145

1 reference

The histological structure of some human lung cancers and the possible implications for radiotherapy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

On the Origin of Cancer Cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Overexpression of vascular endothelial growth factor 165 drives peritumor interstitial convection and induces lymphatic drain: magnetic resonance imaging, confocal microscopy, and histological tracking of triple-labeled albumin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Why are cancers acidic? A carrier-mediated diffusion model for H+ transport in the interstitial fluid

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

A tabulated summary of the FDG PET literature.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Metabolic control: a new solution to an old problem

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Causes and effects of heterogeneous perfusion in tumors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Enhancement of chemotherapy by manipulation of tumour pH.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

The contribution of lactic acid to acidification of tumours: studies of variant cells lacking lactate dehydrogenase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Time-dependent diffusion of water in a biological model system

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

The relevance of tumour pH to the treatment of malignant disease

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Tumorigenic 3T3 cells maintain an alkaline intracellular pH under physiological conditions

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Glucose starvation and acidosis: effect on experimental metastatic potential, DNA content and MTX resistance of murine tumour cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

The ionic components of the current pulses generated by developing fucoid eggs

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Hypoxia activates a platelet-derived growth factor receptor/phosphatidylinositol 3-kinase/Akt pathway that results in glycogen synthase kinase-3 inactivation

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Acidic pH enhances the invasive behavior of human melanoma cells

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Microvascular studies on the origins of perfusion-limited hypoxia

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

The role of fixed and mobile buffers in the kinetics of proton movement

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Reduction of intracellular pH as a possible mechanism for killing cells in acidic regions of solid tumors: effects of carbonylcyanide-3-chlorophenylhydrazone.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Multistage neoplastic transformation of Syrian hamster embryo cells cultured at pH 6.70.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

15 June 2018

Are cancer cells acidic?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Clastogenicity of low pH to various cultured mammalian cells

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Oxygen Diffusion Distance and Development of Necrosis in Multicell Spheroids

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

A stirred bath technique for diffusivity measurements in cell matrices.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Combined vascular and extracellular pH imaging of solid tumors

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

31P-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Warburg Effect Revisited: Merger of Biochemistry and Molecular Biology

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1502399

Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation

19 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659686

12 December 2020

Optimum fiber spacing in a hollow fiber bioreactor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659686

12 December 2020

Theoretical simulation of oxygen transport to tumors by three-dimensional networks of microvessels

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659686

12 December 2020

Pericellular pH affects distribution and secretion of cathepsin B in malignant cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659686

12 December 2020

In vivo imaging of extracellular pH using1H MRSI

2 references

https://pubmed.ncbi.nlm.nih.gov/12659686

12 December 2020

Crossref

https://api.crossref.org/works/10.1016%2FS1476-5586%2803%2980005-2

7 January 2021

inferred from DOI database lookup

Current pulses involving chloride and potassium efflux relieve excess pressure in Pelvetia embryos

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659686

12 December 2020

Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659686

12 December 2020

Buffer-facilitated proton transport. pH profile of bound enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659686

12 December 2020

Mutagenesis induced by the tumor microenvironment

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659686

12 December 2020

Angiogenesis determines blood flow, metabolism, growth rate, and ATPase kinetics of tumors growing in an irradiated bed: 31P and 2H nuclear magnetic resonance studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659686

12 December 2020

Diminished DNA repair and elevated mutagenesis in mammalian cells exposed to hypoxia and low pH

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659686

12 December 2020

Plasmalemmal pH-gradients in drug-sensitive and drug-resistant MCF-7 human breast carcinoma xenografts measured by 31P magnetic resonance spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12659686

12 December 2020

Nm23-transfected MDA-mB-435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: A31P nuclear magnetic resonance study in vivo and in vitro

2 references

https://pubmed.ncbi.nlm.nih.gov/12659686

12 December 2020

Crossref

https://api.crossref.org/works/10.1016%2FS1476-5586%2803%2980005-2

7 January 2021

inferred from DOI database lookup

The Grotthuss mechanism

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FS1476-5586%2803%2980005-2

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1016/S1476-5586(03)80005-2

1 reference

22 September 2017

1 reference

PMC publication ID

1502399

22 September 2017

PubMed publication ID

12659686

1 reference

PMC publication ID

1502399