(Q40657188)

22 September 2017

title

Toll-like receptors 2 and 4 activate STAT1 serine phosphorylation by distinct mechanisms in macrophages (English)

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22 September 2017

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Sang Hoon Rhee

1

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22 September 2017

Bryan W Jones

2

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22 September 2017

Vladimir Toshchakov

3

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22 September 2017

Stefanie N Vogel

4

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22 September 2017

Matthew J Fenton

5

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22 September 2017

language of work or name

English

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publication date

9 April 2003

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Journal of Biological Chemistry

22 September 2017

published in

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22 September 2017

volume

278

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22 September 2017

issue

25

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22 September 2017

page(s)

22506-22512

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A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

22 September 2017

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Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression of the inducible cyclooxygenase

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21 January 2018

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21 January 2018

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21 January 2018

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Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase

21 January 2018

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Serine phosphorylation of STATs

21 January 2018

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Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

21 January 2018

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21 January 2018

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21 January 2018

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TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Roles of phosphatidylinositol 3-kinase in interferon-gamma-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression

21 January 2018

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21 January 2018

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p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons

21 January 2018

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Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway

21 January 2018

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The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

21 January 2018

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Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

21 January 2018

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Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M208633200

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22 September 2017

1 reference