(Q40602477)

21 September 2017

title

Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators (English)

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21 September 2017

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Yanlin Yu

1

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21 September 2017

Javed Khan

2

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21 September 2017

Chand Khanna

3

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21 September 2017

Lee Helman

4

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21 September 2017

Paul S Meltzer

5

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21 September 2017

Glenn Merlino

6

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21 September 2017

language of work or name

English

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publication date

4 January 2004

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21 September 2017

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21 September 2017

volume

10

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21 September 2017

issue

2

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21 September 2017

page(s)

175-181

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describes a project that uses

21 September 2017

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Rhabdomyosarcoma--working out the pathways

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Molecular classification of cutaneous malignant melanoma by gene expression profiling

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Ezrin function is required for ROCK-mediated fibroblast transformation by the Net and Dbl oncogenes

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Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motility

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The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

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ERM proteins: from cellular architecture to cell signaling

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Cell cycle-regulated phosphorylation of the human SIX1 homeodomain protein

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Genomic analysis of metastasis reveals an essential role for RhoC

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Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association

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Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cells

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ERM proteins and NF2 tumor suppressor: the Yin and Yang of cortical actin organization and cell growth signaling

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Rho GTPases in cell biology

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Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein

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The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho

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Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

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Dual stimulation of Ras/mitogen-activated protein kinase and RhoA by cell adhesion to fibronectin supports growth factor-stimulated cell cycle progression

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Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation

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Pax3 and Dach2 positive regulation in the developing somite.

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Altered myogenesis in Six1-deficient mice

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Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site

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Early specification of limb muscle precursor cells by the homeobox gene Lbx1h.

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A system for stable expression of short interfering RNAs in mammalian cells

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Expression profiling in cancer using cDNA microarrays

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Ratio-based decisions and the quantitative analysis of cDNA microarray images

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Ratio statistics of gene expression levels and applications to microarray data analysis

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Analyzing array data using supervised methods.

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Inhibition of nuclear factor-kappaB activity is involved in E1A-mediated sensitization of radiation-induced apoptosis

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Dynamics of beta-catenin interactions with APC protein regulate epithelial tubulogenesis

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An orthotopic model of murine osteosarcoma with clonally related variants differing in pulmonary metastatic potential

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Identifiers

DOI

10.1038/NM966

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Dimensions Publication ID

21 September 2017

1013572427

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1 reference