(Q40601504)

21 September 2017

1 reference

title

5-HT receptors as targets for the development of novel anxiolytic drugs: models, mechanisms and future directions (English)

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21 September 2017

J E Barrett

1

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21 September 2017

K E Vanover

series ordinal

2

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21 September 2017

publication date

1 January 1993

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21 September 2017

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21 September 2017

volume

112

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21 September 2017

issue

1

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21 September 2017

page(s)

1-12

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Behavioural evidence for a functional interaction between central 5-HT2 and 5-HT1A receptors

21 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FBF02247357

Behavioural evidence for functional interactions between 5-HT-receptor subtypes in rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02247357

Effects of the 5-HT3 receptor antagonist, GR38032F, on raised dopaminergic activity in the mesolimbic system of the rat and marmoset brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02247357

Zacopride: anxiolytic profile in rodent and primate models of anxiety

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02247357

The potential anxiolytic activity of GR38032F, a 5-HT3-receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02247357

Effects of buspirone and related compounds on suppressed operant responding in rats.

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

S 14671: a naphtylpiperazine 5-hydroxytryptamine1A agonist of exceptional potency and high efficacy possessing antagonist activity at 5-hydroxytryptamine1C/2 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Increased rates of punished responding produced by buspirone-like compounds in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Autoradiography of serotonin receptor subtypes in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Pharmacology of risperidone (R 64 766), a new antipsychotic with serotonin-S2 and dopamine-D2 antagonistic properties.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Anxiolytic profile of GR 38032F in the potentiated startle paradigm

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Facilitation of 8-OHDPAT-induced forepaw treading of rats by the 5-HT2 agonist DOI

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Behavioural pharmacology of 5-HT3 receptor ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Comparison of acute and chronic treatment of various serotonergic agents with those of diazepam and idazoxan in the rat elevated X-maze

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

5-Hydroxytryptamine1A receptors and behavioral responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Behavioural effects in gerbils of the 5-HT3 receptor antagonists, BRL 43694 and ICS 205-930, under circumstances of high and low light intensity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Effects of drugs on punished behavior: pre-clinical test for anxiolytics

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Buspirone in the management of major depression: a placebo-controlled comparison

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

The main features of central 5-HT1 receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Lack of apparent receptor reserve at postsynaptic 5-hydroxytryptamine1A receptors negatively coupled to adenylyl cyclase activity in rat hippocampal membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Effects of anxiolytic and anxiogenic drugs on exploratory activity in a simple model of anxiety in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

The relation of central 5-HT1A and 5-HT2 receptors: Low dose agonist-induced selective tolerance in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Novel anxiolytics that act as partial agonists at benzodiazepine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

The discovery and development of buspirone: a new approach to the treatment of anxiety

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Serotonin function in anxiety. II. Effects of the serotonin agonist MCPP in panic disorder patients and healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Behavioral pharmacology of antagonists at 5-HT2/5-HT1C receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Alterations of central serotoninergic and dopaminergic neurotransmission in rats chronically treated with ipsapirone: biochemical and electrophysiological studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Comparative studies on the anti-punishment effects of chlordiazepoxide, buspirone and ritanserin in the pigeon, Geller-Seifter and Vogel conflict procedures

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Molecular biology of serotonin receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Multiple populations of serotonin receptors may modulate the behavioral effects of serotonergic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Behavioral studies with anxiolytic drugs. VI. Effects on punished responding of drugs interacting with serotonin receptor subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Blockade of the discriminative stimulus effects of ethanol with 5-HT3 receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

5-HT1A receptor ligands in animal models of anxiety, impulsivity and depression: multiple mechanisms of action?

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Exploration of mice in a black and white test box: validation as a model of anxiety

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Pharmacological validation of a novel animal model of anticipatory anxiety in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Behavioral effects of acute and chronic buspirone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

The effects of 5-HT receptor ligands on ultrasonic calling in mouse pups

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Anxiolytic-like activity of R(+)- and S(-)-zacopride in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

The effects of ondansetron, a 5-HT3 receptor antagonist, on cognition in rodents and primates

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

8-OH-DPAT and buspirone analogs inhibit the ketanserin-sensitive quipazine-induced head shake response in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Effects of tandospirone in three behavioral tests for anxiolytics

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Functional interaction between serotonin-S2 and dopamine-D2 neurotransmission as revealed by selective antagonism of hyper-reactivity to tryptamine and apomorphine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Characterization of MDL 73005EF as a 5-HT1A selective ligand and its effects in animal models of anxiety: comparison with buspirone, 8-OH-DPAT and diazepam

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Chronic administration of the 5-HT3 receptor antagonist BRL 43694; effects on reflex epilepsy and social behaviour of the Mongolian gerbil

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

An ethological study of the effects of buspirone and the 5-HT3 receptor antagonist, BRL 43694 (granisetron) on behaviour during social interactions in female and male mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Neurochemistry and neurophysiology of buspirone and gepirone: interactions at presynaptic and postsynaptic 5-HT1A receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Blockade of acquisition of drug-conditioned place aversion by 5HT3 antagonists.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Reduction in cortical 5HT2 receptor sensitivity after continuous gepirone treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

5-HT1 receptors and behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Effects of the 5-HT3 antagonist GR38032F (ondansetron) on benzodiazepine withdrawal in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

The (S)-isomer of [3H]zacopride labels 5-HT3 receptors with high affinity in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Neuropharmacological and physiological validation of a computer-controlled two-compartment black and white box for the assessment of anxiety

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Lack of effects of 5HT3 receptor antagonists in the social interaction and elevated plus-maze tests of anxiety in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

5-Hydroxytryptamine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

The potent 5-HT3 receptor antagonist (R)-zacopride labels an additional high affinity site in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Do functional relationships exist between 5-HT1A and 5-HT2 receptors?

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Use of buspirone in patients with generalized anxiety disorder and coexisting depressive symptoms. A meta-analysis of eight randomized, controlled studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Pharmacological and clinical effects of buspirone

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Comparative anxiogenic, neuroendocrine, and other physiologic effects of m-chlorophenylpiperazine given intravenously or orally to healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Serotonergic modulation of the rat pup ultrasonic isolation call: studies with 5HT1 and 5HT2 subtype-selective agonists and antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

A quantitative autoradiographic study of serotonin1A receptor regulation. Effect of 5,7-dihydroxytryptamine and antidepressant treatments

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Antagonism of [3H]zacopride binding to 5-HT3 recognition sites by its (R) and (S) enantiomers

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

The influence of ritanserin, a serotonin antagonist, in anxiety disorders: a double-blind placebo-controlled study versus lorazepam

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Regulation of 5-hydroxytryptamine1A receptor function in rat hippocampus by short- and long-term administration of 5-hydroxytryptamine1A agonist and antidepressants

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Agonist/antagonist interactions with cloned human 5-HT1A receptors: variations in intrinsic activity studied in transfected HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Receptor reserve for 5-hydroxytryptamine1A-mediated inhibition of serotonin synthesis: possible relationship to anxiolytic properties of 5-hydroxytryptamine1A agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Ethologically-based animal models of anxiety disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Anxiogenic-like effect of infusing 1-(3-chlorophenyl) piperazine (mCPP) into the hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Evidence that the amygdala is involved in the disinhibitory effects of 5-HT3 receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Latency to enter a mirrored chamber: a novel behavioral assay for anxiolytic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Anticonflict effects of buspirone and chlordiazepoxide in pigeons under a concurrent schedule with punishment and a changeover response

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Molecular Basis of Buspirone's Anxiolytic Action

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

The differential activities of R (+)- and S(-)-zacopride as 5-HT3 receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Zacopride, a 5-HT3 receptor antagonist, reduces voluntary ethanol consumption in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/7870996

12 December 2020

Identifiers

DOI

10.1007/BF02247357

1 reference

Dimensions Publication ID

21 September 2017

1040366562

0 references

1 reference