(Q40596899)

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17 November 2019

title

Molecular determinants involved in the allosteric control of agonist affinity in the GABAB receptor by the GABAB2 subunit (English)

1 reference

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17 November 2019

6

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17 November 2019

Philippe Rondard

7

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17 November 2019

author name string

Jianfeng Liu

1

1 reference

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17 November 2019

Damien Maurel

2

1 reference

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17 November 2019

Sébastien Etzol

3

1 reference

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17 November 2019

Isabelle Brabet

4

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17 November 2019

Hervé Ansanay

5

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17 November 2019

language of work or name

English

0 references

publication date

21 January 2004

1 reference

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Journal of Biological Chemistry

17 November 2019

published in

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17 November 2019

volume

279

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17 November 2019

issue

16

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17 November 2019

page(s)

15824-15830

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GABAB receptors: drugs meet clones.

17 November 2019

cites work

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GABAB receptors: a new paradigm in G protein signaling

21 January 2018

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Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors

21 January 2018

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GABA(B)-receptor subtypes assemble into functional heteromeric complexes.

21 January 2018

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GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2.

21 January 2018

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Heterodimerization is required for the formation of a functional GABA(B) receptor

21 January 2018

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Role of heteromer formation in GABAB receptor function

21 January 2018

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A trafficking checkpoint controls GABA(B) receptor heterodimerization

21 January 2018

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Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function

21 January 2018

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Function of GB1 and GB2 subunits in G protein coupling of GABA(B) receptors

21 January 2018

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A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(B) receptor

21 January 2018

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The intracellular loops of the GB2 subunit are crucial for G-protein coupling of the heteromeric gamma-aminobutyrate B receptor

21 January 2018

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Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding

21 January 2018

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QSAR and molecular modeling studies of baclofen analogues as GABA(B) agonists. Insights into the role of the aromatic moiety in GABA(B) binding and activation.

21 January 2018

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Molecular modeling of the GABA/GABA(B) receptor complex

21 January 2018

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Atomic structures of periplasmic binding proteins and the high-affinity active transport systems in bacteria.

21 January 2018

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Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor

21 January 2018

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Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.

21 January 2018

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Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists

21 January 2018

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Locking the dimeric GABA(B) G-protein-coupled receptor in its active state.

21 January 2018

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G protein-coupled receptor allosterism and complexing

21 January 2018

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Identification of glycoinositol phospholipid linked and truncated forms of the scrapie prion protein

21 January 2018

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A simple method to transfer plasmid DNA into neuronal primary cultures: functional expression of the mGlu5 receptor in cerebellar granule cells

21 January 2018

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The heteromeric GABA-B receptor recognizes G-protein alpha subunit C-termini

21 January 2018

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Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors

21 January 2018

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21 January 2018

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Ligand-induced signal transduction within heterodimeric GABA(B) receptor

21 January 2018

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Ligand binding to the amino-terminal domain of the mGluR4 subtype of metabotropic glutamate receptor

21 January 2018

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Constraints on proper folding of the amino terminal domains of group III metabotropic glutamate receptors

21 January 2018

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Amino acid mutagenesis of the ligand binding site and the dimer interface of the metabotropic glutamate receptor 1. Identification of crucial residues for setting the activated state

21 January 2018

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Mapping the agonist-binding site of GABAB type 1 subunit sheds light on the activation process of GABAB receptors

21 January 2018

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A model for the functioning of family 3 GPCRs

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M313639200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14736871%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference

1 reference