(Q40542008)

English

Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors

scientific article published on 23 June 2004

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scholarly article

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Europe PubMed Central

PubMed publication ID

21 September 2017

Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors (English)

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Europe PubMed Central

PubMed publication ID

21 September 2017

toll-like receptor

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1 reference

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inferred from title

3

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Europe PubMed Central

PubMed publication ID

21 September 2017

author name string

Gary DiPerna

1

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Europe PubMed Central

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21 September 2017

Julianne Stack

2

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Europe PubMed Central

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21 September 2017

Annemarie Boyd

4

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Europe PubMed Central

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21 September 2017

Girish Kotwal

5

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Europe PubMed Central

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21 September 2017

Zhouning Zhang

6

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Europe PubMed Central

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21 September 2017

Sheila Arvikar

7

1 reference

Europe PubMed Central

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21 September 2017

Eicke Latz

8

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Europe PubMed Central

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21 September 2017

Katherine A Fitzgerald

9

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21 September 2017

William L Marshall

10

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21 September 2017

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publication date

23 June 2004

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Europe PubMed Central

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21 September 2017

number of pages

9

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Journal of Biological Chemistry

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21 September 2017

279

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21 September 2017

35

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21 September 2017

36570-36578

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Europe PubMed Central

PubMed publication ID

21 September 2017

A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling.

1 reference

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21 January 2018

Toll-like receptors: critical proteins linking innate and acquired immunity

1 reference

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21 January 2018

TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling

1 reference

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21 January 2018

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

1 reference

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21 January 2018

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

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21 January 2018

The role of Toll-like receptors and MyD88 in innate immune responses

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21 January 2018

TIRAP: an adapter molecule in the Toll signaling pathway

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TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

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TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta.

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Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members

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TAK1 is a ubiquitin-dependent kinase of MKK and IKK

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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NF-kappaB signaling pathways in mammalian and insect innate immunity

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The genome of swinepox virus

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Mapping and insertional mutagenesis of a vaccinia virus gene encoding a 13,800-Da secreted protein

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The vaccinia virus N1L protein is an intracellular homodimer that promotes virulence

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Ph(+) acute lymphoblastic leukemia resistant to the tyrosine kinase inhibitor STI571 has a unique BCR-ABL gene mutation

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21 January 2018

Identification and characterization of an IkappaB kinase

1 reference

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21 January 2018

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

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21 January 2018

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

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Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection

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21 January 2018

Viral appropriation of apoptotic and NF-kappaB signaling pathways

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21 January 2018

Genetic approaches to the study of Toll-like receptor function

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21 January 2018

Structure and function of Toll-like receptor proteins

1 reference

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21 January 2018

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

1 reference

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21 January 2018

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

1 reference

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21 January 2018

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

1 reference

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21 January 2018

Regulation of the NF-kappaB activation pathway by isolated domains of FIP3/IKKgamma, a component of the IkappaB-alpha kinase complex

1 reference

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Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases

1 reference

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21 January 2018

Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

1 reference

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IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

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21 January 2018

Toll-like receptors

1 reference

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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

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Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.

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KSHV vFLIP binds to IKK-gamma to activate IKK.

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NAK is an IkappaB kinase-activating kinase

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NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

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Lymphotoxin-beta-deficient mice show defective antiviral immunity.

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Identifiers

10.1074/JBC.M400567200

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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