(Q40478558)

English

CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms.

scientific article

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms. (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Simian immunodeficiency virus

0 references

object named as

Katy Janvier

2

0 references

Juan S. Bonifacino

object named as

Juan S Bonifacino

5

0 references

Rafick-Pierre Sékaly

4

object named as

Rafick P Sekaly

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

author name string

Jeremy J Rose

1

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Soundararajulu Chandrasekhar

3

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Sundararajan Venkatesan

6

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

language of work or name

0 references

publication date

16 December 2004

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

280

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

7413-7426

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Signals for sorting of transmembrane proteins to endosomes and lysosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Endocytosis and molecular sorting

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Adaptor-related proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Structure--function relationships in HIV-1 Nef.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

In vivo analysis of Nef function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Nef--an adaptor adaptor?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Cluster of differentiation antigen 4 (CD4) endocytosis and adaptor complex binding require activation of the CD4 endocytosis signal by serine phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Myristoylation-dependent binding of HIV-1 Nef to CD4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Nef-CD4 physical interaction sensed with the yeast two-hybrid system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Direct in vitro binding of full-length human immunodeficiency virus type 1 Nef protein to CD4 cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Distinct mechanisms of agonist-induced endocytosis for human chemokine receptors CCR5 and CXCR4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Vaccinia virus expression vector: coexpression of beta-galactosidase provides visual screening of recombinant virus plaques

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Human immunodeficiency virus type 1 (HIV-1) provirus expression and LTR transcription are repressed in NEF-expressing cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Induction of mutant dynamin specifically blocks endocytic coated vesicle formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Beta3A-adaptin, a subunit of the adaptor-like complex AP-3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Nuclear localization of a double-stranded RNA-binding protein encoded by the vaccinia virus E3L gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Differential endocytosis of CD4 in lymphocytic and nonlymphocytic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

The dynamin family of mechanoenzymes: pinching in new places

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Caveolae/raft-dependent endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Genetic analyses of adaptin function from yeast to mammals.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Interactions of HIV-1 nef with the mu subunits of adaptor protein complexes 1, 2, and 3: role of the dileucine-based sorting motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Nef-mediated clathrin-coated pit formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

HIV-1 Nef plays an essential role in two independent processes in CD4 down-regulation: dissociation of the CD4-p56(lck) complex and targeting of CD4 to lysosomes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Nef-induced CD4 downregulation: a diacidic sequence in human immunodeficiency virus type 1 Nef does not function as a protein sorting motif through direct binding to beta-COP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

The di-leucine motif in the cytoplasmic tail of CD4 is not required for binding to human immunodeficiency virus type 1 Nef, but is critical for CD4 down-modulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Regulation and function of the CD3gamma DxxxLL motif: a binding site for adaptor protein-1 and adaptor protein-2 in vitro.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Presence of a Helix in Human CD4 Cytoplasmic Domain Promotes Binding to HIV-1 Nef Protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409420200

21 January 2018

Identifiers

10.1074/JBC.M409420200

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40478558&oldid=1494924279"