(Q40291326)

19 September 2017

1 reference

title

Internalization of polypeptide hormones: mechanism, intracellular localization and significance (English)

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19 September 2017

P Gorden

1

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19 September 2017

J L Carpentier

series ordinal

2

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19 September 2017

P O Freychet

series ordinal

3

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19 September 2017

L Orci

series ordinal

4

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19 September 2017

publication date

1 April 1980

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19 September 2017

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19 September 2017

volume

18

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19 September 2017

issue

4

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19 September 2017

page(s)

263-274

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Binding and degradation of 125I-insulin by rat hepatocytes

19 September 2017

cites work

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Localization of low density lipoprotein receptors on plasma membrane of normal human fibroblasts and their absence in cells from a familial hypercholesterolemia homozygote

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

The nuclear envelope. The major site of insulin binding in rat liver nuclei

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Binding of insulin to isolated nuclei

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Lysosomal association of internalized 125I-insulin in isolated rat hepatocytes. Direct demonstration by quantitative electron microscopic autoradiography

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Insulin-induced receptor loss in the cultured human lymphocyte: quantitative morphological perturbations in the cell and plasma membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Intracellular binding sites for insulin are immunologically distinct from those on the plasma membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

https://pubmed.ncbi.nlm.nih.gov/6998797

1 reference

12 December 2020

Receptor-mediated endocytosis: insights from the lipoprotein receptor system

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Relationship of binding to internalization of125I-insulin in isolated rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Intracellular Translocation of Iodine-125-Labeled Insulin: Direct Demonstration in Isolated Hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture.

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Internalization and degradation of fat cell-bound insulin. Separation and partial characterization of subcellular vesicles associated with iodoinsulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Insulin binding to rat liver Golgi fractions

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Correlation between insulin receptor binding in isolated fat cells and insulin sensitivity in obese human subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Insulin-receptor interaction in the obese-hyperglycemic mouse. A model of insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

An electron microscope autoradiographic study of the carbohydrate recognition systems in rat liver. I. Distribution of 125I-ligands among the liver cell types

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding, and dieting

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

The fate of [125I]iodoepidermal growth factor in isolated hepatocytes: a quantitative electron microscopic autoradiographic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Intracellular polypeptide hormone receptors. Characterization of insulin binding sites in Golgi fractions from the liver of female rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Degradation of Insulin by Isolated Rat Liver Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Genetics of the low density lipoprotein receptor. Diminished receptor activity in lymphocytes from heterozygotes with familial hypercholesterolemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Peptide hormone binding to receptors: a review of direct studies in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Direct visualization of the binding and internalization of a ferritin conjugate of epidermal growth factor in human carcinoma cells A-431

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Insulin interactions with liver plasma membranes. Independence of binding of the hormone and its degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Decreased insulin binding to adipocytes and circulating monocytes from obese subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

The fate of insulin bound to adipocytes. Evidence for compartmentalization and processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Binding and internalization of 125I-LDL in normal and mutant human fibroblasts. A quantitative autoradiographic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Interaction of epidermal growth factor with human fibroblasts in culture: an autoradiographic study at the ultrastructural level

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Insulin Receptor Deficiency in Genetic and Acquired Obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

125I-Insulin is preferentially internalized in regions of the hepatocytes rich in lysosomal and Golgi structures

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Anti-insulin receptor antibodies inhibit insulin binding and stimulate glucose metabolism in skeletal muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

125I-insulin binding to cultured human lymphocytes. Initial localization and fate of hormone determined by quantitative electron microscopic autoradiography

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Symposium III: Hormones and hormone receptors. A morphological approach to surface receptors in islet and liver cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Membrane receptors for hormones and neurotransmitters

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Impairment of insulin binding to the fat cell plasma membrane in the obese hyperglycemic mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

The natural occurrence of insulin receptors in groups on adipocyte plasma membranes as demonstrated with monomeric ferritin-insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Internalization and degradation of receptor-bound hCG in granulosa cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Molecular mechanism of mitogen action: processing of receptor induced by epidermal growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Regulation of receptor concentration by homologous hormone. Effect of human growth hormone on its receptor in IM-9 lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Insulin degradation by lysosomal extracts from rat liver; model for a role of lysosomes in hormone degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Direct demonstration that receptor crosslinking or aggregation is important in insulin action

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Localization of gonadotropic hormones in lysosomes of ovine luteal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

The Banting Memorial Lecture 1976. Insulin today

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Insulin binding to the human lymphocyte receptor. Evaluation of the negative cooperativity model

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Coated pits, coated vesicles, and receptor-mediated endocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Insulin Binding to Monocytes and Insulin Action in Human Obesity, Starvation, and Refeeding

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Degradation of receptor-bound human choriogonadotropin by murine Leydig tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Site-site interactions among insulin receptors. Characterization of the negative cooperativity

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Mode of uptake and degradation of 125I-labelled insulin by isolated hepatocytes and H4 hepatoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Does Insulin Need a Second Messenger?

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Intracellular localization of 125I-labeled insulin in hepatocytes from intact rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Direct visualization of binding, aggregation, and internalization of insulin and epidermal growth factor on living fibroblastic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Defect in insulin binding to receptors in obese man. Amelioration with calorie restriction

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Binding and uptake of 125I-insulin into rat liver hepatocytes and endothelium. An in vivo radioautographic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Direct method for detection and characterization of cell surface receptors for insulin by means of 125I-labeled autoantibodies against the insulin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Cellular uptake and nuclear binding of insulin in human cultured lymphocytes: evidence for potential intracellular sites of insulin action

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Retention and degradation of 125I-insulin by perfused livers from diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Effects of lysosomotropic agents on insulin interactions with adipocytes. Evidence for a lysosomal pathway for insulin processing and degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

An electron microscope autoradiographic study of the carbohydrate recognition systems in rat liver. II. Intracellular fates of the 125I-ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Clathrin: a unique protein associated with intracellular transfer of membrane by coated vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Down regulation of insulin receptors in primary cultures of adult rat hepatocytes in monolayer

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Insulin stimulation of amino acid transport in isolated rat hepatocytes is independent of hormone internalization

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Antibodies That Impair Insulin Receptor Binding in an Unusual Diabetic Syndrome with Severe Insulin Resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Entry of insulin into human cultured lymphocytes: electron microscope autoradiographic analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Studies on the mechanism of capture and degradation of insulin-1131 by the cyclically perfused rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Rapid stimulation of pinocytosis in human carcinoma cells A-431 by epidermal growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Effects of autoantibodies to the insulin receptor on isolated adipocytes. Studies of insulin binding and insulin action

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Newly synthesized acetylcholine receptors are located in the Golgi apparatus

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Ultrastructural localization of insulin receptors on adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Intracellular polypeptide hormone receptors. The demonstration of specific binding sites for insulin and human growth hormone in Golgi fractions isolated from the liver of female rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Metabolism of Insulin and Glucagon. Breakdown of Radioiodinated Insulin and Glucagon in Rat Liver Cell Fractions

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Common features of coated vesicles from dissimilar tissues: Composition and structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/6998797

12 December 2020

Identifiers

DOI

10.1007/BF00251003

1 reference

19 September 2017

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