(Q40115278)

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The adenovirus E1A transforming protein activates the proliferating cell nuclear antigen promoter via an activating transcription factor site

scientific article published on December 1, 1991

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23 September 2019

The adenovirus E1A transforming protein activates the proliferating cell nuclear antigen promoter via an activating transcription factor site (English)

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23 September 2019

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28 October 2022

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28 October 2022

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10.1128/JVI.65.12.6397-6406.1991

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28 October 2022

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10.1128/JVI.65.12.6397-6406.1991

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28 October 2022

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G. F. Morris

1

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28 October 2022

M. B. Mathews

2

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28 October 2022

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1 December 1991

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23 September 2019

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28 October 2022

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28 October 2022

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28 October 2022

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28 October 2022

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28 October 2022

https://journals.asm.org/doi/pdf/10.1128/jvi.65.12.6397-6406.1991

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10.1128/JVI.65.12.6397-6406.1991

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28 October 2022

Journal of Virology

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23 September 2019

65

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23 September 2019

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23 September 2019

6397-6406

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23 September 2019

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

1 reference

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22 September 2017

E1A control of gene expression is mediated by sequences 5' to the transcriptional starts of the early viral genes.

1 reference

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22 September 2017

An enhancer element is located 340 base pairs upstream from the adenovirus-2 E1A capsite

1 reference

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22 September 2017

Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex

1 reference

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22 September 2017

Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses

1 reference

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22 September 2017

Human beta-polymerase gene. Structure of the 5'-flanking region and active promoter

1 reference

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22 September 2017

Adenovirus promoters and E1A transactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Adenovirus E1A coding sequences that enable ras and pmt oncogenes to transform cultured primary cells

1 reference

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22 September 2017

Concentration dependence of transcriptional transactivation in inducible E1A-containing human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

A cellular protein, activating transcription factor, activates transcription of multiple E1A-inducible adenovirus early promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Selective induction of human heat shock gene transcription by the adenovirus E1A gene products, including the 12S E1A product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Multiple functional domains in the adenovirus E1A gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Morphological transformation of established rodent cell lines by high-level expression of the adenovirus type 2 E1a gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Regulation of the proliferating cell nuclear antigen cyclin and thymidine kinase mRNA levels by growth factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Molecular cloning of cDNA coding for rat proliferating cell nuclear antigen (PCNA)/cyclin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Cloning and sequence of the human nuclear protein cyclin: homology with DNA-binding proteins

1 reference

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22 September 2017

Functional identity of proliferating cell nuclear antigen and a DNA polymerase-delta auxiliary protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Cyclin/PCNA is the auxiliary protein of DNA polymerase-delta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Different functional domains of the adenovirus E1A gene are involved in regulation of host cell cycle products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Adenovirus early region 4 encodes two gene products with redundant effects in lytic infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Adenovirus E1A protein paradigm viral transactivator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

The adenovirus E1B 19-kilodalton protein stimulates gene expression by increasing DNA levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Genetic dissection of the transactivating domain of the E1a 289R protein of adenovirus type 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Mechanisms of viral-mediated trans-activation of transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

The "initiator" as a transcription control element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Association of adenovirus early-region 1A proteins with cellular polypeptides

1 reference

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22 September 2017

Transcription initiation from the dihydrofolate reductase promoter is positioned by HIP1 binding at the initiation site

1 reference

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22 September 2017

Transforming collaborations between ras and nuclear oncogenes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Differential effects of the adenovirus E1A oncogene on members of the AP-1 transcription factor family

1 reference

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22 September 2017

Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis

1 reference

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22 September 2017

A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus E1a protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

The efficiency of adenovirus transformation of rodent cells is inversely related to the rate of viral E1A gene expression

1 reference

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22 September 2017

Tandemly repeated hexamer sequences within the beta interferon promoter can function as an inducible regulatory element in activation by the adenovirus E1B 19-kilodalton protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

cis-dominant defect in activation of adenovirus type 5 E1b early RNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Induction of a cellular enzyme for energy metabolism by transforming domains of adenovirus E1a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Heterodimer formation between CREB and JUN proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Analysis of the proliferating cell nuclear antigen promoter and its response to adenovirus early region 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Transcriptional and posttranscriptional regulation of the proliferating cell nuclear antigen gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Molecular cloning, structure and expression of the yeast proliferating cell nuclear antigen gene

1 reference

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22 September 2017

E1A dependent up-regulation of c-jun/AP-1 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

22 September 2017

Positive regulation of jun/AP-1 by E1A

1 reference

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22 September 2017

Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression

1 reference

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22 September 2017

Molecular cloning and structural analysis of mouse gene and pseudogenes for proliferating cell nuclear antigen

1 reference

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22 September 2017

Autoantibody to a nuclear antigen in proliferating cells

1 reference

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22 September 2017

Activation of adenovirus 5 E1A transcription by region E1B in transformed primary rat cells

1 reference

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25 September 2017

An auxiliary protein for DNA polymerase-delta from fetal calf thymus

1 reference

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17 June 2018

Adenovirus E1a proteins repress transcription from the SV40 early promoter

1 reference

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17 June 2018

Transactivation of host and viral genes by the adenovirus E1B 19K tumor antigen.

1 reference

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17 June 2018

Adenovirus transforming 19-kD T antigen has an enhancer-dependent trans-activation function and relieves enhancer repression mediated by viral and cellular genes.

1 reference

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17 June 2018

Detection of cellular proteins associated with human adenovirus type 5 early region 1A polypeptides.

1 reference

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17 June 2018

Induction of transcription factor AP-1 by adenovirus E1A protein and cAMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

17 June 2018

Factor substitution in a human HSP70 gene promoter: TATA-dependent and TATA-independent interactions

1 reference

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17 June 2018

A novel function of the transforming domain of E1a: repression of AP-1 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

17 June 2018

Association of human papillomavirus types 16 and 18 E6 proteins with p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

17 June 2018

Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A trans-activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

17 June 2018

Role of adenovirus E1B proteins in transformation: altered organization of intermediate filaments in transformed cells that express the 19-kilodalton protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

17 June 2018

Sequences in E1A proteins of human adenovirus 5 required for cell transformation, repression of a transcriptional enhancer, and induction of proliferating cell nuclear antigen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

17 June 2018

Transformation-sensitive and growth-related changes of protein synthesis in REF52 cells. A two-dimensional gel analysis of SV40-, adenovirus-, and Kirsten murine sarcoma virus-transformed rat cells using the REF52 protein database

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

17 June 2018

Adenovirus E1A under the control of heterologous promoters: wide variation in E1A expression levels has little effect on virus replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=250676

20 August 2018

Regulation of proliferating cell nuclear antigen during the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for proliferating cell nuclear antigen expression during stages of the Chinese hamster ovary cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human cytomegalovirus major immediate early promoter can be trans-activated by adenovirus early proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An adenovirus early region 4 gene product is required for induction of the infection-specific form of cellular E2F activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cellular proliferation by antisense oligodeoxynucleotides to PCNA cyclin

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

General repression of enhanson activity by the adenovirus-2 E1A proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The REF52 protein database. Methods of database construction and analysis using the QUEST system and characterizations of protein patterns from proliferating and quiescent REF52 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for interaction of different eukaryotic transcriptional activators with distinct cellular targets

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identity of the proliferating cell nuclear antigen and cyclin

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a nuclear and of a cytoplasmic polypeptide whose relative proportions are sensitive to changes in the rate of cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA replication and the early to late transition in adenovirus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of p34, the mammalian homolog of the yeast cdc2+/CDC28 protein kinase, is stimulated during adenovirus-induced proliferation of primary baby rat kidney cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response of individual adenovirus promoters to the products of the E1A gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detailed kinetics of adenovirus type-5 steady-state transcripts during early infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/1682506

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.65.12.6397-6406.1991

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1682506

28 October 2022

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1682506%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1682506%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

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