(Q40013894)

16 September 2017

title

Hepatic overexpression of a dominant negative form of raptor enhances Akt phosphorylation and restores insulin sensitivity in K/KAy mice (English)

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16 September 2017

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4

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16 September 2017

Yuko Koketsu

1

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16 September 2017

Hideyuki Sakoda

2

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16 September 2017

Midori Fujishiro

3

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16 September 2017

Yasushi Fukushima

5

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16 September 2017

Hiraku Ono

6

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16 September 2017

Motonobu Anai

7

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16 September 2017

Takako Kikuchi

8

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16 September 2017

Takeshi Fukuda

9

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16 September 2017

Hideaki Kamata

10

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16 September 2017

Nanao Horike

11

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16 September 2017

Yasunobu Uchijima

12

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16 September 2017

Hiroki Kurihara

13

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16 September 2017

Tomoichiro Asano

14

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16 September 2017

publication date

12 February 2008

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American Journal of Physiology - Endocrinology and Metabolism

16 September 2017

published in

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16 September 2017

volume

294

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16 September 2017

issue

4

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16 September 2017

page(s)

E719-25

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Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor

16 September 2017

cites work

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https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Mammalian TOR: a homeostatic ATP sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Upstream and downstream of mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

A central role for JNK in obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Resistin-like molecule beta activates MAPKs, suppresses insulin signaling in hepatocytes, and induces diabetes, hyperlipidemia, and fatty liver in transgenic mice on a high fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Contribution of salt intake to insulin resistance associated with hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Oxidative stress induces insulin resistance by activating the nuclear factor-kappa B pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Bidirectional modulation of insulin action by amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Phosphoinositide 3-kinase-mediated reduction of insulin receptor substrate-1/2 protein expression via different mechanisms contributes to the insulin-induced desensitization of its signaling pathways in L6 muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Differing Roles of Akt and Serum- and Glucocorticoid-regulated Kinase in Glucose Metabolism, DNA Synthesis, and Oncogenic Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Growing roles for the mTOR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

TOR signaling in growth and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00253.2007

10.1152/AJPENDO.00253.2007

21 January 2018

Identifiers

DOI

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16 September 2017

1 reference