(Q39970013)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18568028%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18568028%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

4

1 reference

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9 January 2020

author name string

Damien Reynaud

1

1 reference

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9 January 2020

Ignacio A Demarco

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18568028%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Karen L Reddy

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18568028%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Eric Bertolino

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18568028%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Zhengshan Chen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18568028%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Stephen T Smale

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18568028%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Susan Winandy

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18568028%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Harinder Singh

9

1 reference

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9 January 2020

language of work or name

English

0 references

publication date

22 June 2008

1 reference

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9 January 2020

1 reference

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9 January 2020

volume

9

1 reference

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9 January 2020

issue

8

1 reference

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9 January 2020

page(s)

927-936

1 reference

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describes a project that uses

9 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2699484/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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22 September 2017

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22 September 2017

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Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5

22 September 2017

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Foxp1 is an essential transcriptional regulator of B cell development

22 September 2017

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Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus

22 September 2017

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Early hematopoietic lineage restrictions directed by Ikaros.

22 September 2017

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Ikaros-family proteins: in search of molecular functions during lymphocyte development.

22 September 2017

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PU.1 is not strictly required for B cell development and its absence induces a B-2 to B-1 cell switch

22 September 2017

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Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5.

22 September 2017

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Genetic networks that regulate B lymphopoiesis

22 September 2017

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Contingent gene regulatory networks and B cell fate specification

22 September 2017

1 reference

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Ikaros induces quiescence and T-cell differentiation in a leukemia cell line.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription.

22 September 2017

1 reference

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How to keep V(D)J recombination under control

22 September 2017

1 reference

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Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A

22 September 2017

1 reference

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Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis

22 September 2017

1 reference

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IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development

22 September 2017

1 reference

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Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development

22 September 2017

1 reference

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Haematopoietic cell-fate decisions, chromatin regulation and ikaros

22 September 2017

1 reference

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Stepwise activation of the immunoglobulin mu heavy chain gene locus

22 September 2017

1 reference

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Down-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activator

22 September 2017

1 reference

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Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Defects in hemopoietic stem cell activity in Ikaros mutant mice

22 September 2017

1 reference

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Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Distinct factors regulate the murine RAG-2 promoter in B- and T-cell lines

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

The Ikaros gene is required for the development of all lymphoid lineages

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

V(D)J recombination and the cell cycle.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Characterization of chromatin structure and enhancer elements for murine recombination activating gene-2.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Identification and characterization of the murine Rag1 promoter

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Complete sequence assembly and characterization of the C57BL/6 mouse Ig heavy chain V region

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

The mechanism of repression of the myeloid-specific c-fms gene by Pax5 during B lineage restriction

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Epigenetic ontogeny of the Igk locus during B cell development

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Assembling a gene regulatory network for specification of the B cell fate

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Antisense intergenic transcription in V(D)J recombination

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

A conserved transcriptional enhancer regulates RAG gene expression in developing B cells.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

The CD8alpha gene locus is regulated by the Ikaros family of proteins.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Ikaros is critical for B cell differentiation and function.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699484

Thymopoiesis independent of common lymphoid progenitors

20 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/18568028

12 December 2020

Coordinate regulation of RAG1 and RAG2 by cell type-specific DNA elements 5' of RAG2

1 reference

https://pubmed.ncbi.nlm.nih.gov/18568028

12 December 2020

Characterization of the proximal enhancer element and transcriptional regulatory factors for murine recombination activating gene-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/18568028

12 December 2020

A recombination silencer that specifies heterochromatin positioning and ikaros association in the immunoglobulin kappa locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18568028

12 December 2020

Identifiers

DOI

10.1038/NI.1626

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18568028%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18568028%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

18568028

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18568028%20AND%20SRC:MED&resulttype=core&format=json