(Q39910112)

15 September 2017

title

Gadd45-alpha and Gadd45-gamma utilize p38 and JNK signaling pathways to induce cell cycle G2/M arrest in Hep-G2 hepatoma cells (English)

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15 September 2017

main subject

hepatocellular carcinoma

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Na Zhu

1

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15 September 2017

Yan Shao

2

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15 September 2017

Lin Xu

3

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15 September 2017

Long Yu

4

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15 September 2017

Luhong Sun

5

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15 September 2017

publication date

2 December 2008

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Molecular Biology Reports

15 September 2017

published in

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15 September 2017

volume

36

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15 September 2017

issue

8

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15 September 2017

page(s)

2075-2085

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The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth

15 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS11033-008-9419-9

Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-008-9419-9

Down-regulation of growth arrest DNA damage-inducible gene 45beta expression is associated with human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-008-9419-9

Three GADD45 isoforms contribute to hypertonic stress phenotype of murine renal inner medullary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11033-008-9419-9

CR6-interacting factor 1 interacts with Gadd45 family proteins and modulates the cell cycle

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

Tumor suppressors and oncogenes in cellular senescence.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

Reduction of insulin-stimulated glucose uptake in L6 myotubes by the protein kinase inhibitor SB203580 is independent of p38MAPK activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

GADD45 induction of a G2/M cell cycle checkpoint

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

The Jun N-terminal kinase inhibitor SP600125 is a ligand and antagonist of the aryl hydrocarbon receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

Gadd45 is a nuclear cell cycle regulated protein which interacts with p21Cip1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

Characterization of MyD118, Gadd45, and proliferating cell nuclear antigen (PCNA) interacting domains. PCNA impedes MyD118 AND Gadd45-mediated negative growth control

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

GADD45 regulates G2/M arrest, DNA repair, and cell death in keratinocytes following ultraviolet exposure

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

GADD45gamma, down-regulated in 65% hepatocellular carcinoma (HCC) from 23 chinese patients, inhibits cell growth and induces cell cycle G2/M arrest for hepatoma Hep-G2 cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

Hematopoietic cells from gadd45a-deficient and gadd45b-deficient mice exhibit impaired stress responses to acute stimulation with cytokines, myeloablation and inflammation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

The differentiation primary response gene MyD118, related to GADD45, encodes for a nuclear protein which interacts with PCNA and p21WAF1/CIP1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

Gadd45a protects against UV irradiation-induced skin tumors, and promotes apoptosis and stress signaling via MAPK and p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

Hyperosmolality causes growth arrest of murine kidney cells. Induction of GADD45 and GADD153 by osmosensing via stress-activated protein kinase 2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

NF-κB-mediated repression of growth arrest- and DNA-damage-inducible proteins 45α and γ is essential for cancer cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

14-3-3sigma is a p53-regulated inhibitor of G2/M progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

GADD45-induced cell cycle G2-M arrest associates with altered subcellular distribution of cyclin B1 and is independent of p38 kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/19048389

12 December 2020

10.1007/S11033-008-9419-9

Identifiers

DOI

1 reference

15 September 2017

1 reference