(Q39509936)

12 September 2017

1 reference

title

Cachectin/tumor necrosis factor: an endogenous mediator of shock and inflammation (English)

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12 September 2017

B Beutler

1

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12 September 2017

A Cerami

series ordinal

2

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12 September 2017

publication date

1 January 1986

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12 September 2017

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12 September 2017

volume

5

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12 September 2017

issue

4

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12 September 2017

page(s)

281-293

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The Primary Role of Lymphoreticnlar Cells in the Mediation of Host Responses to Bacterial Endotoxim

12 September 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF02935501

Genetic control of lipopolysaccharide induced generation of serum colony stimulating factor and proliferation of splenic granulocyte/macrophage precursor cells

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Tumor necrosis factor: specific binding and internalization in sensitive and resistant cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Is platelet activating factor (PAF) a mediator of endotoxin shock?

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Activation of Lyt-1+ and Lyt-2+ T cell cloned lines: stimulation of proliferation, lymphokine production, and self-destruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Purification and partial amino acid sequence of rabbit tumor necrosis factor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Modulation of endothelial cell hemostatic properties by tumor necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Genetic analysis of generation of serum interferon by bacterial lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Vascular reactions of normal and malignant tissues in vivo. V. The rôle of hypotension in the action of a bacterial polysaccharide on tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

An endothelial cell surface factor(s) induced in vitro by lipopolysaccharide, interleukin 1, and tumor necrosis factor-alpha increases neutrophil adherence by a CDw18-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Activity of recombinant tumor necrosis factor on Toxoplasma gondii and Trypanosoma cruzi

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Platelet activating factor (PAF) involvement in endotoxin-induced hypotension in rats. Studies with PAF-receptor antagonist kadsurenone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Control of cachectin (tumor necrosis factor) synthesis: mechanisms of endotoxin resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Interferons and tumor necrosis factors have similar catabolic effects on 3T3 L1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Tumor necrosis factor receptors in HeLa cells and their regulation by interferon-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Effect of gamma interferon on cachectin expression by mononuclear phagocytes. Reversal of the lpsd (endotoxin resistance) phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Tumor necrosis factor induction by Sendai virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Tumor necrosis factor and lymphotoxin induce differentiation of human myeloid cell lines in synergy with immune interferon

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Morphologic changes in rabbits following the intravenous administration of meningococcal toxin. I. The effects produced in young and in mature animals by a single injection

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Identity of differentiation inducing factor and tumour necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Cachectin/tumor necrosis factor: production, distribution, and metabolic fate in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Tumor necrosis factor induces synthesis of two proteins in human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Gamma interferon and lymphotoxin, released by activated T cells, synergize to inhibit granulocyte/monocyte colony formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Molecular cloning of the gene encoding rabbit tumor necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Studies of endotoxin-induced decrease in lipoprotein lipase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

The genetic mapping of a defective LPS response gene in C3H/HeJ mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Molecular cloning and expression in Escherichia coli of the cDNA coding for rabbit tumor necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Mediation of mouse natural cytotoxic activity by tumour necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Requirement for the continual presence of lipopolysaccharide for production of tumor necrosis factor by thioglycollate-induced peritoneal murine macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Molecular cloning of mouse tumour necrosis factor cDNA and its eukaryotic expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Macrophage sensitivity to endotoxin: genetic control by a single codominant gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Human lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Elicitation of endotoxemic effects in C3H/HeJ mice with glucocorticoid antagonizing factor and partial characterization of the factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Generation of slow-reacting substance (leukotrienes) by endotoxin and lipid A from human polymorphonuclear granulocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

A macrophage factor inhibits adipocyte gene expression: an in vitro model of cachexia

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Natural killer (NK) cell-derived hematopoietic colony-inhibiting activity and NK cytotoxic factor. Relationship with tumor necrosis factor and synergism with immune interferon

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Induction of the synthesis of tumor necrosis factor receptors by interferon-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Effect of tumour necrosis factor on cultured human melanoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Recombinant interleukin 1 suppresses lipoprotein lipase activity in 3T3-L1 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Endotoxin and tumor necrosis factor induce interleukin-1 gene expression in adult human vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Induction of beta 2-interferon by tumor necrosis factor: a homeostatic mechanism in the control of cell proliferation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Actions of tumor necrosis factor on cultured vascular endothelial cells: morphologic modulation, growth inhibition, and cytotoxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Cloning and expression in Escherichia coli of the cDNA for murine tumor necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Hypertriglyceridemia associated with Trypanosoma brucei brucei infection in rabbits: role of defective triglyceride removal.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Weight loss associated with an endotoxin-induced mediator from peritoneal macrophages: the role of cachectin (tumor necrosis factor).

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Genetic non-responsiveness of murine fibroblasts to bacterial endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

An endotoxin-induced serum factor that causes necrosis of tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Activation of human polymorphonuclear neutrophil functions by interferon-gamma and tumor necrosis factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Tumor necrosis factor enhances eosinophil toxicity to Schistosoma mansoni larvae

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Recombinant human tumor necrosis factor increases mRNA levels and surface expression of HLA-A,B antigens in vascular endothelial cells and dermal fibroblasts in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Pathologic Changes Produced in Rabbits by a Toxic Somatic Antigen Derived from Eberthella Typhosa.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Human tumor necrosis factor. Production, purification, and characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Molecular cloning of the complementary DNA for human tumor necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

The treatment of malignant tumors by repeated inoculations of erysipelas. With a report of ten original cases. 1893.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Purification of rabbit tumor necrosis factor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Demonstration of membrane receptors for human natural and recombinant 125I-labeled tumor necrosis factor on HeLa cell clones and their role in tumor cell sensitivity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Leukotriene antagonists prevent endotoxin lethality

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Lipoprotein lipase suppression in 3T3-L1 cells by an endotoxin-induced mediator from exudate cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Genetic Control of Leucocyte Responses to Endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Effect of interleukin 2, interferon-gamma, and mitogens on the production of tumor necrosis factors alpha and beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Journal of the National Cancer Institute, Vol. 29, 1962: Action of bacterial polysaccharide on tumors. II. Damage of sarcoma 37 by serum of mice treated with Serratia marcescens polysaccharide, and induced tolerance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Modulation of receptors and cytotoxic response of tumor necrosis factor-alpha by various lectins

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Tumor necrosis factor stimulates interleukin-1 and prostaglandin E2 production in resting macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Cellular receptor for 125I-labeled tumor necrosis factor: specific binding, affinity labeling, and relationship to sensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Shock and tissue injury induced by recombinant human cachectin

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/3036973

12 December 2020

Identifiers

DOI

10.1007/BF02935501

1 reference

12 September 2017

1 reference