(Q38798543)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

author

Alexander N Shoushtari

80

1 reference

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19 March 2020

Bernard H Bochner

86

1 reference

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19 March 2020

Ahmet Zehir

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Ronak H Shah

3

1 reference

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19 March 2020

Sumit Middha

5

1 reference

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19 March 2020

Hyunjae (Ryan) Kim

6

1 reference

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19 March 2020

Jianjiong Gao

8

1 reference

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19 March 2020

Jaclyn F Hechtman

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Anoop Balakrishnan Rema

28

1 reference

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19 March 2020

Jacklyn Casanova

33

1 reference

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19 March 2020

Angelica Ochoa

56

1 reference

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19 March 2020

Stacy B Thomas

59

1 reference

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19 March 2020

Dalicia N Reales

61

1 reference

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19 March 2020

Darren R Feldman

67

1 reference

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19 March 2020

Gopa Iyer

71

1 reference

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19 March 2020

Maeve Lowery

75

1 reference

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19 March 2020

Pedram Razavi

79

1 reference

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19 March 2020

92

David S Klimstra

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

68

Mrinal M Gounder

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

89

Howard I Scher

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

93

Barry S Taylor

1 reference

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19 March 2020

author name string

Ryma Benayed

2

1 reference

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19 March 2020

Aijazuddin Syed

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Preethi Srinivasan

7

1 reference

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19 March 2020

Debyani Chakravarty

9

1 reference

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19 March 2020

Sean M Devlin

10

1 reference

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19 March 2020

Matthew D Hellmann

11

1 reference

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19 March 2020

David A Barron

12

1 reference

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19 March 2020

Alison M Schram

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Meera Hameed

14

1 reference

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19 March 2020

Snjezana Dogan

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Dara S Ross

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Deborah F DeLair

18

1 reference

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19 March 2020

JinJuan Yao

19

1 reference

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19 March 2020

Diana L Mandelker

20

1 reference

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19 March 2020

Donavan T Cheng

21

1 reference

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19 March 2020

Raghu Chandramohan

22

1 reference

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19 March 2020

Abhinita S Mohanty

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Ryan N Ptashkin

24

1 reference

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19 March 2020

Gowtham Jayakumaran

25

1 reference

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19 March 2020

Meera Prasad

26

1 reference

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19 March 2020

Mustafa H Syed

27

1 reference

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19 March 2020

Zhen Y Liu

29

1 reference

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19 March 2020

Khedoudja Nafa

30

1 reference

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19 March 2020

Laetitia Borsu

31

1 reference

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19 March 2020

Justyna Sadowska

32

1 reference

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19 March 2020

Ruben Bacares

34

1 reference

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19 March 2020

Iwona J Kiecka

35

1 reference

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19 March 2020

Anna Razumova

36

1 reference

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19 March 2020

Julie B Son

37

1 reference

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19 March 2020

Lisa Stewart

38

1 reference

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19 March 2020

Tessara Baldi

39

1 reference

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19 March 2020

Kerry A Mullaney

40

1 reference

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19 March 2020

Hikmat Al-Ahmadie

41

1 reference

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19 March 2020

Efsevia Vakiani

42

1 reference

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19 March 2020

Adam A Abeshouse

43

1 reference

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19 March 2020

Alexander V Penson

44

1 reference

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19 March 2020

Philip Jonsson

45

1 reference

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19 March 2020

Niedzica Camacho

46

1 reference

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19 March 2020

Matthew T Chang

47

1 reference

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19 March 2020

Helen H Won

48

1 reference

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19 March 2020

Benjamin E Gross

49

1 reference

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19 March 2020

Ritika Kundra

50

1 reference

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19 March 2020

Zachary J Heins

51

1 reference

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19 March 2020

Hsiao-Wei Chen

52

1 reference

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19 March 2020

Sarah Phillips

53

1 reference

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19 March 2020

Hongxin Zhang

54

1 reference

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19 March 2020

Jiaojiao Wang

55

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Jonathan Wills

57

1 reference

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19 March 2020

Michael Eubank

58

1 reference

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19 March 2020

Stuart M Gardos

60

1 reference

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19 March 2020

Jesse Galle

62

1 reference

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19 March 2020

Robert Durany

63

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19 March 2020

Roy Cambria

64

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Wassim Abida

65

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19 March 2020

Andrea Cercek

66

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19 March 2020

A Ari Hakimi

69

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19 March 2020

James J Harding

70

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19 March 2020

Yelena Y Janjigian

72

1 reference

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19 March 2020

Emmet J Jordan

73

1 reference

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19 March 2020

Ciara M Kelly

74

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19 March 2020

Luc G T Morris

76

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19 March 2020

Antonio M Omuro

77

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19 March 2020

Nitya Raj

78

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19 March 2020

Neerav Shukla

81

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19 March 2020

Tara E Soumerai

82

1 reference

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19 March 2020

Anna M Varghese

83

1 reference

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19 March 2020

Rona Yaeger

84

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19 March 2020

Jonathan Coleman

85

1 reference

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19 March 2020

Gregory J Riely

87

1 reference

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19 March 2020

Leonard B Saltz

88

1 reference

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19 March 2020

Paul J Sabbatini

90

1 reference

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19 March 2020

Mark E Robson

91

1 reference

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19 March 2020

David M Hyman

96

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19 March 2020

Maria E Arcila

97

1 reference

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19 March 2020

David B Solit

98

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19 March 2020

Michael F Berger

100

1 reference

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19 March 2020

Jose Baselga

94

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Nikolaus Schultz

95

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Marc Ladanyi

99

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

language of work or name

English

0 references

publication date

8 May 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

page(s)

703-713

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

COSMIC: somatic cancer genetics at high-resolution

19 March 2020

cites work

1 reference

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Institutional implementation of clinical tumor profiling on an unselected cancer population

22 June 2018

1 reference

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Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial.

22 June 2018

1 reference

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The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine

22 June 2018

1 reference

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A combinatorial strategy for treating KRAS-mutant lung cancer

22 June 2018

1 reference

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Automated eligibility screening and monitoring for genotype-driven precision oncology trials.

22 June 2018

1 reference

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Massively parallel sequencing of phyllodes tumours of the breast reveals actionable mutations, and TERT promoter hotspot mutations and TERT gene amplification as likely drivers of progression

22 June 2018

1 reference

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Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

22 June 2018

1 reference

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Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer

22 June 2018

1 reference

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TERT promoter mutations and long telomere length predict poor survival and radiotherapy resistance in gliomas

22 June 2018

1 reference

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Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA.

22 June 2018

1 reference

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BRAF Mutants Evade ERK-Dependent Feedback by Different Mechanisms that Determine Their Sensitivity to Pharmacologic Inhibition

22 June 2018

1 reference

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The distribution of BRAF gene fusions in solid tumors and response to targeted therapy

22 June 2018

1 reference

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Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations

22 June 2018

1 reference

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Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response.

22 June 2018

1 reference

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Clinical activity of the MEK inhibitor trametinib in metastatic melanoma containing BRAF kinase fusion

22 June 2018

1 reference

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PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Personalized genomic analyses for cancer mutation discovery and interpretation

22 June 2018

1 reference

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On the Road to Precision Cancer Medicine: Analysis of Genomic Biomarker Actionability in 439 Patients

22 June 2018

1 reference

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Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

The landscape and therapeutic relevance of cancer-associated transcript fusions.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Integrated genomic characterization of papillary thyroid carcinoma

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Validation of a next-generation-sequencing cancer panel for use in the clinical laboratory.

22 June 2018

1 reference

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The landscape of kinase fusions in cancer

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Advancing clinical oncology through genome biology and technology.

22 June 2018

1 reference

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The somatic genomic landscape of chromophobe renal cell carcinoma

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Comprehensive molecular characterization of gastric adenocarcinoma

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

ABRA: improved coding indel detection via assembly-based realignment

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Contribution of p53 to metastasis

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

TERT promoter mutations are a major indicator of poor outcome in differentiated thyroid carcinomas

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

MSIsensor: microsatellite instability detection using paired tumor-normal sequence data

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

ESR1 ligand-binding domain mutations in hormone-resistant breast cancer

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Activating ESR1 mutations in hormone-resistant metastatic breast cancer

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Mutational landscape and significance across 12 major cancer types

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Emerging landscape of oncogenic signatures across human cancers

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Signatures of mutational processes in human cancer

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Clinical validation of a next-generation sequencing screen for mutational hotspots in 46 cancer-related genes.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Punctuated evolution of prostate cancer genomes

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Genomics-driven oncology: framework for an emerging paradigm

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Highly recurrent TERT promoter mutations in human melanoma

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

TERT promoter mutations in familial and sporadic melanoma

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

DELLY: structural variant discovery by integrated paired-end and split-read analysis

22 June 2018

1 reference

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The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

22 June 2018

1 reference

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Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Personalized oncology through integrative high-throughput sequencing: a pilot study

22 June 2018

1 reference

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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

22 June 2018

1 reference

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Improved survival with vemurafenib in melanoma with BRAF V600E mutation

22 June 2018

1 reference

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The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

22 June 2018

1 reference

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Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Fast and accurate short read alignment with Burrows-Wheeler transform

22 June 2018

1 reference

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The UCSC Table Browser data retrieval tool

22 June 2018

1 reference

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The protein kinase complement of the human genome

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Comprehensive Genomic Profiling of Carcinoma of Unknown Primary Site: New Routes to Targeted Therapies.

22 June 2018

1 reference

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Anchored multiplex PCR for targeted next-generation sequencing

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

Molecular Testing Guideline for Selection of Lung Cancer Patients for EGFR and ALK Tyrosine Kinase Inhibitors

11 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5461196

OncoKB: A Precision Oncology Knowledge Base

3 December 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.4333

inferred from DOI database lookup

7 January 2021

based on heuristic

Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies.

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.4333

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NM.4333

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28481359%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

PubMed publication ID

28481359

1 reference