(Q38360608)

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A di-leucine motif and an upstream serine in the interleukin-6 (IL-6) signal transducer gp130 mediate ligand-induced endocytosis and down-regulation of the IL-6 receptor

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Europe PubMed Central

PubMed publication ID

2 September 2017

A di-leucine motif and an upstream serine in the interleukin-6 (IL-6) signal transducer gp130 mediate ligand-induced endocytosis and down-regulation of the IL-6 receptor (English)

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Europe PubMed Central

PubMed publication ID

2 September 2017

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author name string

Dittrich E

1

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Europe PubMed Central

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2 September 2017

Haft CR

2

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2 September 2017

Muys L

3

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2 September 2017

Heinrich PC

4

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2 September 2017

Graeve L

5

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2 September 2017

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publication date

1 March 1996

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2 September 2017

Journal of Biological Chemistry

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2 September 2017

271

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2 September 2017

10

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Europe PubMed Central

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2 September 2017

5487-5494

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Europe PubMed Central

PubMed publication ID

2 September 2017

Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

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Regulation of synthesis and secretion of major rat acute-phase proteins by recombinant human interleukin-6 (BSF-2/IL-6) in hepatocyte primary cultures

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Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis

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The molecular cell biology of interferon-gamma and its receptor

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Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells

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Molecular regulation of B lymphocyte response

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A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains

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Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

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Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction

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IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase

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The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits

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Preparation of monoclonal antibodies against the IL-6 signal transducer, gp130, that can inhibit IL-6-mediated functions

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Structural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cells

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Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

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Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor

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The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family

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Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

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Acute-phase response of human hepatocytes: Regulation of acute-phase protein synthesis by interleukin-6

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Identifiers

10.1074/JBC.271.10.5487

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

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