(Q37801965)

23 August 2017

title

Potential clinical applications of siRNA technique: benefits and limitations (English)

1 reference

23 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20964680

7 August 2024

author name string

Shao-Hua Chen

1

1 reference

23 August 2017

Getu Zhaori

2

1 reference

23 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20964680

7 August 2024

publication date

22 October 2010

1 reference

full work available at URL

23 August 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2362.2010.02400.x

1 reference

https://api.crossref.org/works/10.1111/J.1365-2362.2010.02400.X

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2362.2010.02400.x/fullpdf

7 August 2024

1 reference

https://api.crossref.org/works/10.1111/J.1365-2362.2010.02400.X

European Journal of Clinical Investigation

7 August 2024

published in

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23 August 2017

volume

41

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23 August 2017

issue

2

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23 August 2017

page(s)

221-232

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Applications of RNA interference: current state and prospects for siRNA-based strategies in vivo

23 August 2017

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Chemical modification of siRNAs for in vivo use.

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Toxicogenomics of non-viral drug delivery systems for RNAi: potential impact on siRNA-mediated gene silencing activity and specificity

21 January 2018

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First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder.

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RNAi-based treatment for neovascular age-related macular degeneration by Sirna-027.

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RNA interference for therapy in the vascular endothelium

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RNAi-mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease-9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth.

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Depletion of procathepsin D gene expression by RNA interference: a potential therapeutic target for breast cancer

21 January 2018

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Twist1-mediated adriamycin-induced epithelial-mesenchymal transition relates to multidrug resistance and invasive potential in breast cancer cells

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Inhibitory effect of siRNA targeting survivin in gastric cancer MGC-803 cells

21 January 2018

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Oncolytic adenovirus mediated Survivin knockdown by RNA interference suppresses human colorectal carcinoma growth in vitro and in vivo

21 January 2018

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Knockdown of survivin expression by siRNAs enhances chemosensitivity of prostate cancer cells and attenuates its tumorigenicity

21 January 2018

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STAT3: a target to enhance antitumor immune response

21 January 2018

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Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice.

21 January 2018

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IL-6, but not IFN-gamma, triggers apoptosis and inhibits in vivo growth of human malignant T cells on STAT3 silencing.

21 January 2018

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Vascular endothelial growth factor and vascular endothelial growth factor receptor inhibitors as anti-angiogenic agents in cancer therapy

21 January 2018

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Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer

21 January 2018

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Synthesis and biological evaluation of a bioresponsive and endosomolytic siRNA-polymer conjugate.

21 January 2018

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Antibody-mediated targeting of siRNA via the human insulin receptor using avidin-biotin technology

21 January 2018

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Inhibition of non-small cell lung cancer cell proliferation and tumor growth by vector-based small interfering RNAs targeting HER2/neu

21 January 2018

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Antiapoptotic activity of autocrine interleukin-22 and therapeutic effects of interleukin-22-small interfering RNA on human lung cancer xenografts.

21 January 2018

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A small interfering RNA targeting osteopontin as gastric cancer therapeutics

21 January 2018

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Inhibition of osteopontin would suppress angiogenesis in gastric cancer

21 January 2018

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Adenovirus-mediated down-regulation of X-linked inhibitor of apoptosis protein inhibits colon cancer

21 January 2018

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Therapeutic targeting of Id2 reduces growth of human colorectal carcinoma in the murine liver

21 January 2018

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A small interfering RNA targeting proteinase-activated receptor-2 is effective in suppression of tumor growth in a Panc1 xenograft model

21 January 2018

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Regression of prostate cancer xenografts by RLIP76 depletion

21 January 2018

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HMGA2 gene is a promising target for ovarian cancer silencing therapy

21 January 2018

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Gemcitabine-based chemogene therapy for pancreatic cancer using Ad-dCK::UMK GDEPT and TS/RR siRNA strategies

21 January 2018

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Trastuzumab-induced cardiotoxicity

21 January 2018

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Inhibition of hepatitis C virus infection and expression in vitro and in vivo by recombinant adenovirus expressing short hairpin RNA.

21 January 2018

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RNA interference against hepatitis B virus with endoribonuclease-prepared siRNA despite of the target sequence variations

21 January 2018

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RNA interference-mediated silencing of the respiratory syncytial virus nucleocapsid defines a potent antiviral strategy

21 January 2018

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Cardiac-targeted RNA interference mediated by an AAV9 vector improves cardiac function in coxsackievirus B3 cardiomyopathy

21 January 2018

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21 January 2018

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21 January 2018

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Activation of hypoxia-inducible factor-1 via prolyl-4 hydoxylase-2 gene silencing attenuates acute inflammatory responses in postischemic myocardium

21 January 2018

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21 January 2018

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In vivo SPECT and real-time gamma camera imaging of biodistribution and pharmacokinetics of siRNA delivery using an optimized radiolabeling and purification procedure

21 January 2018

1 reference

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RNAi-based drug discovery and its application to therapeutics

21 January 2018

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Imaging of cationic multifunctional liposome-mediated delivery of COX-2 siRNA.

7 August 2024

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1 reference

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Stat3-siRNA induces Fas-mediated apoptosis in vitro and in vivo in breast cancer

7 August 2024

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1 reference

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Combined silencing of K-ras and Akt2 oncogenes achieves synergistic effects in inhibiting pancreatic cancer cell growth in vitro and in vivo

7 August 2024

28

1 reference

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A novel in vivo siRNA delivery system specifically targeting dendritic cells and silencing CD40 genes for immunomodulation

7 August 2024

31

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Intravenous injection of siRNA directed against hypoxia-inducible factors prolongs survival in a Lewis lung carcinoma cancer model

7 August 2024

36

1 reference

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Lentivirus-mediated short hairpin RNA targeting the APRIL gene suppresses the growth of pancreatic cancer cells in vitro and in vivo

7 August 2024

41

1 reference

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Liposomal siRNA for ovarian cancer

7 August 2024

44

1 reference

https://api.crossref.org/works/10.1111/J.1365-2362.2010.02400.X

7 August 2024

Identifiers

1 reference

23 August 2017

1 reference