(Q37726811)

22 August 2017

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase (English)

1 reference

22 August 2017

endoplasmic reticulum

0 references

author name string

O Thastrup

1

1 reference

22 August 2017

P J Cullen

2

1 reference

22 August 2017

B K Drøbak

3

1 reference

22 August 2017

M R Hanley

4

1 reference

22 August 2017

A P Dawson

5

1 reference

22 August 2017

language of work or name

English

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publication date

1 April 1990

1 reference

Proceedings of the National Academy of Sciences of the United States of America

22 August 2017

1 reference

22 August 2017

87

1 reference

22 August 2017

7

1 reference

22 August 2017

2466-2470

1 reference

Protein measurement with the Folin phenol reagent

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Preparation and morphology of sarcoplasmic reticulum terminal cisternae from rabbit skeletal muscle

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

A new generation of Ca2+ indicators with greatly improved fluorescence properties

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Analysis of the stimulative effect of thapsigargin, a non-TPA-type tumour promoter, on arachidonic acid metabolism in rat peritoneal macrophages

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

A C-terminal, calmodulin-like regulatory domain from the plasma membrane Ca2+-pumping ATPase

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Cyclic GMP-dependent protein kinase stimulates the plasmalemmal Ca2+ pump of smooth muscle via phosphorylation of phosphatidylinositol

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Molecular cloning of cDNAs from human kidney coding for two alternatively spliced products of the cardiac Ca2+-ATPase gene

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

A model for receptor-regulated calcium entry

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Regulation of the Ca2+ pump ATPase by cAMP-dependent phosphorylation of phospholamban

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Neural function: metabolism and actions of inositol metabolites in mammalian brain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Thapsigargine and thapsigargicine, two new histamine liberators from Thapsia garganica L.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Purification of the Ca2+-stimulated ATPase activator from human erythrocytes. Its membership in the class of Ca2+-binding modulator proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

The calcium mobilizing tumor promoting agent, thapsigargin elevates the platelet cytoplasmic free calcium concentration to a higher steady state level. A possible mechanism of action for the tumor promotion

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Accumulation of triacylglycerol in cultured rat hepatocytes is increased by ethanol and by insulin and dexamethasone

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Some properties of the Ca2+-stimulated ATPase of a rat liver microsomal fraction

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

The mechanism of action of GTP on Ca2+ efflux from rat liver microsomal vesicles

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

The mechanism of action of GTP on Ca2+ efflux from rat liver microsomal vesicles. Measurement of vesicle fusion by fluorescence energy transfer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

A novel tumour promoter, thapsigargin, transiently increases cytoplasmic free Ca2+ without generation of inositol phosphates in NG115-401L neuronal cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

A model for the uptake and release of Ca2+ by sarcoplasmic reticulum

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Palytoxin is a non-12-O-tetradecanoylphorbol-13-acetate type tumor promoter in two-stage mouse skin carcinogenesis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Internal Ca2+ mobilization and secretion in bovine adrenal chromaffin cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Transient kinetics of Ca2+ transport of sarcoplasmic reticulum. A comparison of cardiac and skeletal muscle

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Thapsigargin, a new calcium-dependent epithelial anion secretagogue

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53710

Inositol (1,4,5)trisphosphate-promoted Ca2+ release from microsomal fractions of rat liver

1 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/2138778

12 December 2020

GTP enhances inositol trisphosphate-stimulated Ca2+ release from rat liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2138778

12 December 2020

Inositol trisphosphate induces calcium release from nonmitochondrial stores i sea urchin egg homogenates

1 reference

https://pubmed.ncbi.nlm.nih.gov/2138778

12 December 2020

Effects of chelating agents on the Ca2+-stimulated ATPase of rat liver plasma membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2138778

12 December 2020

Thapsigargin, a histamine secretagogue, is a non-12-O-tetradecanolphorbol-13-acetate (TPA) type tumor promoter in two-stage mouse skin carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2138778

12 December 2020

The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations

1 reference

https://pubmed.ncbi.nlm.nih.gov/2138778

12 December 2020

A glucagon fragment is responsible for the inhibition of the liver Ca2+ pump by glucagon

1 reference

https://pubmed.ncbi.nlm.nih.gov/2138778

12 December 2020

Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relation to AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/2138778

12 December 2020

Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. Evidence that an intracellular calcium pool and not an inositol phosphate regulates calcium fluxes at the plasma membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/2138778

12 December 2020

Ca2+ transients and Mn2+ entry in human neutrophils induced by thapsigargin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2138778

12 December 2020

Identifiers

DOI

10.1073/PNAS.87.7.2466

1 reference

22 August 2017

0 references

1 reference

22 August 2017

PubMed publication ID

2138778

1 reference