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The stressed CNS: when glucocorticoids aggravate inflammation.
scientific article published on October 2009
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scholarly article
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Europe PubMed Central
PMC publication ID
4782919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19840546%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
review article
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Europe PubMed Central
title
The stressed CNS: when glucocorticoids aggravate inflammation
(English)
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stated in
Europe PubMed Central
PMC publication ID
4782919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19840546%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
main subject
inflammation
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author
Shawn F Sorrells
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
4782919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19840546%20AND%20SRC:MED&resulttype=core&format=json
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10 February 2020
Javier R Caso
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2
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Europe PubMed Central
PMC publication ID
4782919
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19840546%20AND%20SRC:MED&resulttype=core&format=json
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10 February 2020
Robert Sapolsky
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4
object named as
Robert M Sapolsky
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Europe PubMed Central
PMC publication ID
4782919
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10 February 2020
author name string
Carolina D Munhoz
series ordinal
3
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Europe PubMed Central
PMC publication ID
4782919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19840546%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
language of work or name
English
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publication date
1 October 2009
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Europe PubMed Central
PMC publication ID
4782919
reference URL
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retrieved
10 February 2020
published in
Neuron
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Europe PubMed Central
PMC publication ID
4782919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19840546%20AND%20SRC:MED&resulttype=core&format=json
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10 February 2020
volume
64
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Europe PubMed Central
PMC publication ID
4782919
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19840546%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
issue
1
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Europe PubMed Central
PMC publication ID
4782919
reference URL
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10 February 2020
page(s)
33-39
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Europe PubMed Central
PMC publication ID
4782919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19840546%20AND%20SRC:MED&resulttype=core&format=json
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10 February 2020
cites work
Stressor-specific alterations in corticosterone and immune responses in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
23 August 2017
NF-kappa B as a therapeutic target in neurodegenerative diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
23 August 2017
Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
23 August 2017
Fast glucocorticoid actions on brain: back to the future
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
23 August 2017
Glucocorticoid therapy in neurologic critical care
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
23 August 2017
The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
23 August 2017
Crosstalk between glucocorticoids and mitogen-activated protein kinase signalling pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
23 August 2017
The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
23 August 2017
Inducible nitric oxide synthase expression in brain cortex after acute restraint stress is regulated by nuclear factor kappaB-mediated mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
23 August 2017
Glucocorticoids, stress, and their adverse neurological effects: relevance to aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
23 August 2017
Brain corticosteroid receptor balance in health and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
23 August 2017
Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
23 August 2017
Microglia: a sensor for pathological events in the CNS
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
23 August 2017
Identification of endogenous glucocorticoid repressed genes differentially regulated by a glucocorticoid receptor mutant able to separate between nuclear factor-kappaB and activator protein-1 repression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
6 September 2017
Stress and hippocampal plasticity: implications for the pathophysiology of affective disorders
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
6 September 2017
Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
6 September 2017
Macrophage migration inhibitory factor promotes innate immune responses by suppressing glucocorticoid-induced expression of mitogen-activated protein kinase phosphatase-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
14 September 2017
The role of mitogen-activated protein kinase phosphatase-1 in the response of alveolar macrophages to lipopolysaccharide: attenuation of proinflammatory cytokine biosynthesis via feedback control of p38.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
14 September 2017
Glucocorticoid pretreatment induces cytokine overexpression and nuclear factor-kappaB activation in macrophages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
14 September 2017
Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions*
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
14 September 2017
Immunoendocrine communication via the hypothalamo-pituitary-adrenal axis in autoimmune diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
28 September 2017
Mitogen-activated protein kinase cascades as regulators of stress responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
25 June 2018
Acute stress enhances while chronic stress suppresses cell-mediated immunity in vivo: a potential role for leukocyte trafficking
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
25 June 2018
Glucocorticoids potentiate ischemic injury to neurons: therapeutic implications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
25 June 2018
Prior exposure to glucocorticoids sensitizes the neuroinflammatory and peripheral inflammatory responses to E. coli lipopolysaccharide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
1 September 2018
Stress mediators regulate brain prostaglandin synthesis and peroxisome proliferator-activated receptor-gamma activation after stress in rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
1 September 2018
Corticosterone as a marker of susceptibility to oxidative/nitrosative cerebral damage after stress exposure in rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
1 September 2018
Involvement of IL-1beta in acute stress-induced worsening of cerebral ischaemia in rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
1 September 2018
The role of tumor necrosis factor-alpha in stress-induced worsening of cerebral ischemia in rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
1 September 2018
Stress increases vulnerability to inflammation in the rat prefrontal cortex.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
1 September 2018
Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
1 September 2018
Chronic unpredictable stress exacerbates lipopolysaccharide-induced activation of nuclear factor-kappaB in the frontal cortex and hippocampus via glucocorticoid secretion.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
1 September 2018
Stress-induced elevation of glucocorticoids increases microglia proliferation through NMDA receptor activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
1 September 2018
Catecholamines mediate stress-induced increases in peripheral and central inflammatory cytokines.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
1 September 2018
Induction of cyclooxygenase-2 accounts for restraint stress-induced oxidative status in rat brain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
1 September 2018
Novel glucocorticoid effects on acute inflammation in the CNS.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
1 September 2018
Prior stressor exposure sensitizes LPS-induced cytokine production.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
1 September 2018
The increase in TNF-alpha levels is implicated in NF-kappaB activation and inducible nitric oxide synthase expression in brain cortex after immobilization stress.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
1 September 2018
Immunoendocrine Communication via the Hypothalamo-Pituitary-Adrenal Axis in Autoimmune Diseases*
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
1 September 2018
Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4782919
retrieved
3 December 2018
Restraint stress-induced thymic involution and cell apoptosis are dependent on endogenous glucocorticoids
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19840546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Control of enzymatic synthesis of adrenaline in the adrenal medulla by adrenal cortical steroids
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19840546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The role of adrenocorticoids as modulators of immune function in health and disease: neural, endocrine and immune interactions
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19840546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Stress Downregulates Lipopolysaccharide-Induced Expression of Proinflammatory Cytokines in the Spleen, Pituitary, and Brain of Mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19840546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Effects of glucocorticoids and norepinephrine on the excitability in the hippocampus
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19840546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Glucocorticoid conditioning of myeloid progenitors enhances TLR4 signaling via negative regulation of the phosphatidylinositol 3-kinase-Akt pathway
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19840546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19840546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Stress-induced changes in blood leukocyte distribution. Role of adrenal steroid hormones
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19840546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.NEURON.2009.09.032
1 reference
stated in
Europe PubMed Central
PMC publication ID
4782919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19840546%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
PMC publication ID
4782919
1 reference
stated in
Europe PubMed Central
PMC publication ID
4782919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19840546%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
PubMed publication ID
19840546
1 reference
stated in
Europe PubMed Central
PMC publication ID
4782919
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19840546%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
ResearchGate publication ID
38021614
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