(Q37476789)

20 August 2017

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title

The role of autophagy in sensitizing malignant glioma cells to radiation therapy (English)

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adaptive radiation therapy

20 August 2017

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author name string

Wenzhuo Zhuang

series ordinal

1

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20 August 2017

Zhenghong Qin

series ordinal

2

1 reference

20 August 2017

Zhongqin Liang

series ordinal

3

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20 August 2017

publication date

1 May 2009

1 reference

Acta Biochimica et Biophysica Sinica

20 August 2017

published in

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20 August 2017

volume

41

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20 August 2017

issue

5

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20 August 2017

page(s)

341-351

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Validation and predictive power of Radiation Therapy Oncology Group (RTOG) recursive partitioning analysis classes for malignant glioma patients: a report using RTOG 90-06.

20 August 2017

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Exploiting different ways to die.

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Runx1 prevents wasting, myofibrillar disorganization, and autophagy of skeletal muscle

21 January 2018

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Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy

21 January 2018

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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

21 January 2018

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3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

21 January 2018

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Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

21 January 2018

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Identification of human brain tumour initiating cells

21 January 2018

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Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

21 January 2018

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Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

21 January 2018

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Cancerous stem cells can arise from pediatric brain tumors

21 January 2018

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The phosphoinositide 3-kinase pathway

21 January 2018

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The protein kinase B/Akt signalling pathway in human malignancy

21 January 2018

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PI3K/Akt/mTOR pathway as a target for cancer therapy

21 January 2018

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21 January 2018

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21 January 2018

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Activation of the PI3K/Akt pathway and chemotherapeutic resistance

21 January 2018

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Exploiting the PI3K/AKT pathway for cancer drug discovery

21 January 2018

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PKB/Akt mediates radiosensitization by the signaling inhibitor LY294002 in human malignant gliomas.

21 January 2018

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Inhibition of phosphatidylinositol-3-kinase causes increased sensitivity to radiation through a PKB-dependent mechanism

21 January 2018

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Rapamycin alleviates toxicity of different aggregate-prone proteins

21 January 2018

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A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells

21 January 2018

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Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling.

21 January 2018

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Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells

21 January 2018

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Double strand break repair

21 January 2018

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Molecular mechanisms of DNA double strand break repair

21 January 2018

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Structure of DNA-dependent protein kinase: implications for its regulation by DNA.

21 January 2018

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Low and high LET radiation‐induced apoptosis in M059J and M059K cells

21 January 2018

1 reference

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Different G2/M accumulation in M059J and M059K cells after exposure to DNA double-strand break-inducing agents.

21 January 2018

1 reference

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The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest

21 January 2018

1 reference

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DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53.

21 January 2018

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DNA damage checkpoint control in cells exposed to ionizing radiation

21 January 2018

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DNA-PK phosphorylation sites in XRCC4 are not required for survival after radiation or for V(D)J recombination

21 January 2018

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DNA-dependent protein kinase acts upstream of p53 in response to DNA damage

21 January 2018

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Functional interaction between DNA-PK and c-Abl in response to DNA damage

21 January 2018

1 reference

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21 January 2018

Surfing the p53 network

1 reference

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DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

21 January 2018

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The coordinate regulation of the p53 and mTOR pathways in cells

21 January 2018

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The role of p53 in determining sensitivity to radiotherapy

21 January 2018

1 reference

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Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy

21 January 2018

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The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway

21 January 2018

1 reference

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Defective autophagy leads to cancer

21 January 2018

1 reference

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Beclin 1 augmented cis-diamminedichloroplatinum induced apoptosis via enhancing caspase-9 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma

21 January 2018

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Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

21 January 2018

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An integrated genomic analysis of human glioblastoma multiforme

21 January 2018

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

21 January 2018

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The mitochondrial permeability transition initiates autophagy in rat hepatocytes.

21 January 2018

1 reference

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Discrimination of depolarized from polarized mitochondria by confocal fluorescence resonance energy transfer

21 January 2018

1 reference

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Autophagy delays apoptotic death in breast cancer cells following DNA damage

21 January 2018

1 reference

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Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells

21 January 2018

1 reference

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Radiation-induced cell death: importance of lysosomal destabilization

21 January 2018

1 reference

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Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Crosstalk between Bak/Bax and mTOR signaling regulates radiation-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Endoplasmic reticulum stress triggers autophagy

21 January 2018

1 reference

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Autophagy as a cell death and tumor suppressor mechanism

21 January 2018

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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

21 January 2018

1 reference

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Inhibition of N-(4-hydroxyphenyl)retinamide-induced autophagy at a lower dose enhances cell death in malignant glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Tumour stem cells and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

21 January 2018

1 reference

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21 January 2018

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Targeting cancer stem cells through L1CAM suppresses glioma growth

21 January 2018

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Prospective identification of tumorigenic prostate cancer stem cells

21 January 2018

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A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

21 January 2018

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Cancer stem cells in radiation resistance.

21 January 2018

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Cell cycle checkpoint signaling through the ATM and ATR kinases

21 January 2018

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DNA structure dependent checkpoints as regulators of DNA repair

21 January 2018

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The DNA damage response: putting checkpoints in perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Preclinical Characterization of the Antiglioma Activity of a Tropism-Enhanced Adenovirus Targeted to the Retinoblastoma Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

Induction of cytotoxic T lymphocytes specific to malignant glioma using T2 cells pulsed with HLA-A2-restricted interleukin-13 receptor alpha 2 peptide in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMP028

21 January 2018

Identifiers

DOI

10.1093/ABBS/GMP028

1 reference

20 August 2017

1 reference