(Q37377572)

20 August 2017

Lin28 promotes transformation and is associated with advanced human malignancies (English)

1 reference

20 August 2017

24

George Q Daley

0 references

Srinivas R Viswanathan

Srinivas R Viswanathan

1

0 references

Jose M Teixeira

Jose Teixeira

16

0 references

Charles G. Mullighan

Charles G Mullighan

21

0 references

Josep M. Llovet

Josep M Llovet

19

0 references

Matthew Meyerson

17

Matthew Meyerson

1 reference

20 August 2017

13

Craig H Mermel

1 reference

20 August 2017

22

Todd R Golub

1 reference

20 August 2017

14

Rameen Beroukhim

1 reference

20 August 2017

3

William Einhorn

1 reference

20 August 2017

11

Samar P Shah

1 reference

20 August 2017

John T Powers

2

1 reference

20 August 2017

Yujin Hoshida

4

1 reference

20 August 2017

Tony L Ng

5

1 reference

20 August 2017

Sara Toffanin

6

1 reference

20 August 2017

Maureen O'Sullivan

7

1 reference

20 August 2017

Jun Lu

8

1 reference

20 August 2017

Letha A Phillips

9

1 reference

20 August 2017

Victoria L Lockhart

10

1 reference

20 August 2017

Pradeep S Tanwar

12

1 reference

20 August 2017

Mohammad Azam

15

1 reference

20 August 2017

Timothy P Hughes

18

1 reference

20 August 2017

Jerald Radich

20

1 reference

20 August 2017

Poul H Sorensen

23

1 reference

20 August 2017

language of work or name

English

0 references

publication date

31 May 2009

1 reference

20 August 2017

1 reference

20 August 2017

41

1 reference

20 August 2017

7

1 reference

20 August 2017

843-848

1 reference

Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Gene expression in fixed tissues and outcome in hepatocellular carcinoma.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Activation of tyrosine kinases by mutation of the gatekeeper threonine

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Focal gains of VEGFA and molecular classification of hepatocellular carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

The let-7 microRNA reduces tumor growth in mouse models of lung cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Suppression of non-small cell lung tumor development by the let-7 microRNA family

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Selective blockade of microRNA processing by Lin28

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Reprogramming of human somatic cells to pluripotency with defined factors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

let-7 regulates self renewal and tumorigenicity of breast cancer cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Induced pluripotent stem cell lines derived from human somatic cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

let-7 microRNA expression is reduced in bronchioloalveolar carcinoma, a non-invasive carcinoma, and is not correlated with prognosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Let-7 expression defines two differentiation stages of cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

The tumor suppressor microRNA let-7 represses the HMGA2 oncogene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Impaired microRNA processing enhances cellular transformation and tumorigenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

The Spemann organizer gene, Goosecoid, promotes tumor metastasis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Extensive post-transcriptional regulation of microRNAs and its implications for cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Functional analysis of human hematopoietic stem cell gene expression using zebrafish

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

MicroRNA expression profiles classify human cancers

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Origins and molecular pathology of ovarian cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Analysis of array CGH data: from signal ratio to gain and loss of DNA regions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

The transcriptome profile of human embryonic stem cells as defined by SAGE

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

6 September 2017

Hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Detection of a novel t(6;15)(q21;q21) in a pediatric Wilms tumor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Physical localisation of the breakpoints of a constitutional translocation t(5;6)(q21;q21) in a child with bilateral Wilms' tumour.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

bcr/abl and src but not myc and ras replace v-abl in lymphoid transformation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Detailed characterization of a homozygously deleted region corresponding to a candidate tumor suppressor locus at 21q11-21 in human lung cancer.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Homozygous deletion scanning of the lung cancer genome at a 100-kb resolution

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Differential expression of a novel ankyrin containing E3 ubiquitin-protein ligase, Hace1, in sporadic Wilms' tumor versus normal kidney

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Role of the tyrosine phosphatase SHP-1 in K562 cell differentiation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Molecular cytogenetic analysis of adult testicular germ cell tumours and identification of regions of consensus copy number change

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Fibroblast lines expressing activated c-myc oncogenes are tumorigenic in nude mice and syngeneic animals

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Quantitative expression analysis in peripheral blood of patients with chronic myeloid leukaemia: correlation between HMGA2 expression and white blood cell count.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Gains at the 1p36 chromosomal region are associated with symptomatic leptomeningeal dissemination of supratentorial glioblastomas.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757943

Molecular analysis of region t(5;6)(q21;q21) in Wilms tumor

2 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19483683

12 December 2020

inferred from PubMed ID database lookup

Oct-3/4 is a dose-dependent oncogenic fate determinant

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19483683

12 December 2020

inferred from PubMed ID database lookup

Hypermethylation of let-7a-3 in epithelial ovarian cancer is associated with low insulin-like growth factor-II expression and favorable prognosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19483683

12 December 2020

inferred from PubMed ID database lookup

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.392

7 January 2021

inferred from DOI database lookup

Identifiers

1 reference

https://api.fatcat.wiki/v0/release/tfyn7i7cu5hdvpngl3xkv4lhte

30 July 2022

release_tfyn7i7cu5hdvpngl3xkv4lhte

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tfyn7i7cu5hdvpngl3xkv4lhte

30 July 2022

https://api.fatcat.wiki/v0/release/tfyn7i7cu5hdvpngl3xkv4lhte

1 reference

30 July 2022

https://api.fatcat.wiki/v0/release/tfyn7i7cu5hdvpngl3xkv4lhte

PubMed publication ID

1 reference

30 July 2022