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English
Lonidamine induces apoptosis in drug-resistant cells independently of the p53 gene.
scientific article published on September 1996
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
title
Lonidamine induces apoptosis in drug-resistant cells independently of the p53 gene
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
main subject
apoptotic process
0 references
author
Donatella Del Bufalo
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
Silvia Soddu
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
author name string
Biroccio A
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
Laudonio N
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
D'Angelo C
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
Sacchi A
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
Zupi G
series ordinal
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
language of work or name
English
0 references
publication date
1 September 1996
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
published in
Journal of Clinical Investigation
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
volume
98
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
issue
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
page(s)
1165-1173
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
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p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression
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6 September 2017
Reversal of adriamycin resistance by lonidamine in a human breast cancer cell line
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6 September 2017
Apoptosis: molecular mechanisms in programmed cell death
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6 September 2017
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
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6 September 2017
Transgenic mice that express the human multidrug-resistance gene in bone marrow enable a rapid identification of agents that reverse drug resistance
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Bcl-2: a repressor of lymphocyte death
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Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal.
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28 September 2017
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26 June 2018
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26 June 2018
Enhancement of cisplatin activity by lonidamine in human ovarian cancer cells
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507539
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26 June 2018
Comparative evaluation of several DNA binding dyes in the detection of apoptosis-associated chromatin degradation by flow cytometry
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26 June 2018
Apoptosis: the cell cycle and cell death.
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2 September 2018
Wild-type p53-triggered apoptosis is inhibited by bcl-2 in a v-myc-induced T-cell lymphoma line.
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2 September 2018
p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507539
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2 September 2018
Cytotoxic effect of the association of BCNU with rhein or lonidamine on a human glioma cell line.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507539
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2 September 2018
On the mechanism of action of lonidamine: a study on human erythrocyte membrane
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=507539
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2 October 2018
Glucose metabolism in drug-sensitive and drug-resistant human breast cancer cells monitored by magnetic resonance spectroscopy
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8787680
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Multidrug resistance
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8787680
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8787680
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The MRP gene associated with a non-P-glycoprotein multidrug resistance encodes a 190-kDa membrane bound glycoprotein
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8787680
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
bcl-2 and other genomic alterations in the prognosis of large-cell lymphoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8787680
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Involvement of the bcl-2 gene in human follicular lymphoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8787680
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
NAD depletion after in vitro exposure of murine lung slices to bleomycin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8787680
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Lonidamine significantly increases the activity of epirubicin in patients with advanced breast cancer: results from a multicenter prospective randomized trial
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8787680
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Intracellular localization of the antitumour drug adriamycin in living cultured cells: a confocal microscopy study
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8787680
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A model for the computer analysis of synchronous DNA distributions obtained by flow cytometry
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8787680
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Wild-type p53 gene expression induces granulocytic differentiation of HL-60 cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8787680
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Modulation of adriamycin uptake by lonidamine in Ehrlich ascites tumor cells
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8787680
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8787680
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8787680
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1172/JCI118900
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
PMC publication ID
507539
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
PubMed publication ID
8787680
1 reference
stated in
Europe PubMed Central
PMC publication ID
507539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8787680%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
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