(Q37255877)

19 August 2017

1 reference

title

Inflamed adipose tissue, insulin resistance and vascular injury (English)

1 reference

19 August 2017

1 reference

Christian X Andersson

1

1 reference

19 August 2017

Birgit Gustafson

2

1 reference

19 August 2017

Ann Hammarstedt

3

1 reference

19 August 2017

Shahram Hedjazifar

4

1 reference

19 August 2017

Ulf Smith

5

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19 August 2017

publication date

1 November 2008

1 reference

Diabetes - Metabolism: Research and Reviews

19 August 2017

published in

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19 August 2017

volume

24

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19 August 2017

issue

8

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19 August 2017

page(s)

595-603

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PKC-theta knockout mice are protected from fat-induced insulin resistance

19 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

Obesity is associated with macrophage accumulation in adipose tissue

21 January 2018

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https://api.crossref.org/works/10.1002%2FDMRR.889

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

Inflamed adipose tissue: a culprit underlying the metabolic syndrome and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Inflammation and metabolic disorders

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

TLR4 links innate immunity and fatty acid-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Role of the Toll-like receptor 4/NF-kappaB pathway in saturated fatty acid-induced inflammatory changes in the interaction between adipocytes and macrophages

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Attenuation of obesity-induced adipose tissue inflammation in C3H/HeJ mice carrying a Toll-like receptor 4 mutation

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Systemic inflammation, adipose tissue tumor necrosis factor, and leptin expression.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Adipose angiotensinogen is involved in adipose tissue growth and blood pressure regulation

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Chemokines control fat accumulation and leptin secretion by cultured human adipocytes

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Monocyte chemoattractant protein 1 in obesity and insulin resistance

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Mesenteric adipose tissue-derived monocyte chemoattractant protein-1 plays a crucial role in adipose tissue macrophage migration and activation in obese mice

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

A unique role of monocyte chemoattractant protein 1 among chemokines in adipose tissue of obese subjects.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Association between the A-2518G polymorphism in the monocyte chemoattractant protein-1 gene and insulin resistance and Type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

PAI-1 and the metabolic syndrome: links, causes, and consequences

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Progression of plasminogen activator inhibitor-1 and fibrinogen levels in relation to incident type 2 diabetes

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Bone marrow plasminogen activator inhibitor-1 influences the development of obesity.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Plasminogen activator inhibitor-1 modulates adipocyte differentiation.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Associations between insulin resistance and TNF-alpha in plasma, skeletal muscle and adipose tissue in humans with and without type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

TNFalpha release by the nonfat cells of human adipose tissue

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Adipose tissue, inflammation, and cardiovascular disease

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Circulating interleukin 6 levels, blood pressure, and insulin sensitivity in apparently healthy men and women.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Circulating interleukin-6 in relation to adiposity, insulin action, and insulin secretion

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Inflammation: the link between insulin resistance, obesity and diabetes

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

High local concentrations and effects on differentiation implicate interleukin-6 as a paracrine regulator

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Insulin resistance due to phosphorylation of insulin receptor substrate-1 at serine 302.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

The role of chemokines in neutrophil biology

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

The role of chemokines in human cardiovascular pathology: enhanced biological insights

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Association between measures of insulin sensitivity and circulating levels of interleukin-8, interleukin-6 and tumor necrosis factor-alpha. Effect of weight loss in obese men.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Serum amyloid A: production by human white adipocyte and regulation by obesity and nutrition

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Adipocyte-derived serum amyloid A3 and hyaluronan play a role in monocyte recruitment and adhesion

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Nonexpression of the Human Serum Amyloid A Three (SAA3) Gene

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Diet-induced weight loss is associated with decreases in plasma serum amyloid a and C-reactive protein independent of dietary macronutrient composition in obese subjects

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Serum amyloid A is a ligand for scavenger receptor class B type I and inhibits high density lipoprotein binding and selective lipid uptake

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Decrease in serum adiponectin level due to obesity and visceral fat accumulation in children

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Decreased serum levels of adiponectin are a risk factor for the progression to type 2 diabetes in the Japanese Population: the Funagata study

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Adiponectin and the development of type 2 diabetes: the atherosclerosis risk in communities study

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Evidence of impaired adipogenesis in insulin resistance

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Enlarged subcutaneous abdominal adipocyte size, but not obesity itself, predicts type II diabetes independent of insulin resistance

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Monocyte chemoattractant protein-1 in subcutaneous abdominal adipose tissue: characterization of interstitial concentration and regulation of gene expression by insulin

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Monocyte chemoattractant protein-1 is produced in isolated adipocytes, associated with adiposity and reduced after weight loss in morbid obese subjects.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

CCR2 modulates inflammatory and metabolic effects of high-fat feeding

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Inhibition of adipogenesis by Wnt signaling

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

TCF7L2 and type 2 diabetes--we WNT to know

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Wnt-signaling is maintained and adipogenesis inhibited by TNFalpha but not MCP-1 and resistin

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

AdipoQ is a novel adipose-specific gene dysregulated in obesity

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Weight Reduction Increases Plasma Levels of an Adipose-Derived Anti-Inflammatory Protein, Adiponectin

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Adiponectin gene activation by thiazolidinediones requires PPAR gamma 2, but not C/EBP alpha-evidence for differential regulation of the aP2 and adiponectin genes

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Lipid and lipoprotein dysregulation in insulin resistant states

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Insulin antagonizes interleukin-6 signaling and is anti-inflammatory in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

The effect of PPARgamma ligands on the adipose tissue in insulin resistance

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Improved insulin sensitivity and adipose tissue dysregulation after short-term treatment with pioglitazone in non-diabetic, insulin-resistant subjects

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

TNF-α induces endothelial dysfunction in diabetic adults, an effect reversible by the PPAR-γ agonist pioglitazone

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Combined adipocyte-macrophage fatty acid-binding protein deficiency improves metabolism, atherosclerosis, and survival in apolipoprotein E-deficient mice.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Understanding hyperlipidemia and atherosclerosis: lessons from genetically modified apoe and ldlr mice

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https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Role of macrophage tissue infiltration in metabolic diseases.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

"Vasocrine" signalling from perivascular fat: a mechanism linking insulin resistance to vascular disease.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Echocardiographic Epicardial Adipose Tissue Is Related to Anthropometric and Clinical Parameters of Metabolic Syndrome: A New Indicator of Cardiovascular Risk

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Production of chemokines by perivascular adipose tissue: a role in the pathogenesis of atherosclerosis?

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Human epicardial adipose tissue is a source of inflammatory mediators

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Human epicardial adipose tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular disease

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Blood monocytes consist of two principal subsets with distinct migratory properties

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Adiponectin actions in the cardiovascular system

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Adipose tissue and atherosclerosis: exploring the connection

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Adipocytokines: mediators linking adipose tissue, inflammation and immunity

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Relationship of adiponectin with markers of systemic inflammation, atherogenic dyslipidemia, and heart failure in patients with coronary heart disease

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Adiponectin induces the anti-inflammatory cytokines IL-10 and IL-1RA in human leukocytes

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

AMPK inhibits fatty acid-induced increases in NF-kappaB transactivation in cultured human umbilical vein endothelial cells.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Adiponectin stimulates production of nitric oxide in vascular endothelial cells.

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Adiponectin improves endothelial function in hyperlipidemic rats by reducing oxidative/nitrative stress and differential regulation of eNOS/iNOS activity

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells

1 reference

https://api.crossref.org/works/10.1002%2FDMRR.889

7 January 2021

Identifiers

DOI

10.1002/DMRR.889

1 reference

19 August 2017

1 reference