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Uracil in DNA: consequences for carcinogenesis and chemotherapy
scientific article published on July 2008
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scholarly article
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Europe PubMed Central
PMC publication ID
2562027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18599024%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
Uracil in DNA: consequences for carcinogenesis and chemotherapy
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2562027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18599024%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
main subject
chemotherapy
1 reference
based on heuristic
inferred from title
carcinogenesis
1 reference
based on heuristic
inferred from title
author
Michael D Wyatt
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2562027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18599024%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
author name string
Sondra H Berger
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2562027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18599024%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
Douglas L Pittman
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2562027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18599024%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
language of work or name
English
0 references
publication date
1 July 2008
1 reference
stated in
Europe PubMed Central
PMC publication ID
2562027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18599024%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
published in
Biochemical Pharmacology
1 reference
stated in
Europe PubMed Central
PMC publication ID
2562027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18599024%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
volume
76
1 reference
stated in
Europe PubMed Central
PMC publication ID
2562027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18599024%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
issue
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
2562027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18599024%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
page(s)
697-706
1 reference
stated in
Europe PubMed Central
PMC publication ID
2562027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18599024%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
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DNA instability (strand breakage, uracil misincorporation, and defective repair) is increased by folic acid depletion in human lymphocytes in vitro
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Folate depletion in human lymphocytes up-regulates p53 expression despite marked induction of strand breaks in exons 5-8 of the gene.
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11 August 2018
Differential roles of checkpoint kinase 1, checkpoint kinase 2, and mitogen-activated protein kinase-activated protein kinase 2 in mediating DNA damage-induced cell cycle arrest: implications for cancer therapy.
1 reference
stated in
PubMed Central
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11 August 2018
Imbalanced base excision repair in response to folate deficiency is accelerated by polymerase beta haploinsufficiency
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PubMed Central
reference URL
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11 August 2018
Uracil in DNA, determined by an improved assay, is increased when deoxynucleosides are added to folate-deficient cultured human lymphocytes
1 reference
stated in
PubMed Central
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11 August 2018
Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas
1 reference
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PubMed Central
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11 August 2018
Expression of uracil DNA glycosylase (UDG) does not affect cellular sensitivity to thymidylate synthase (TS) inhibition
1 reference
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PubMed Central
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11 August 2018
dUTPase and uracil-DNA glycosylase are central modulators of antifolate toxicity in Saccharomyces cerevisiae.
1 reference
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PubMed Central
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11 August 2018
Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency.
1 reference
stated in
PubMed Central
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11 August 2018
Resistance to fluorodeoxyuridine-induced DNA damage and cytotoxicity correlates with an elevation of deoxyuridine triphosphatase activity and failure to accumulate deoxyuridine triphosphate.
1 reference
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PubMed Central
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11 August 2018
Relationship of dUMP and free FdUMP pools to inhibition of thymidylate synthase by 5-fluorouracil
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/18599024
retrieved
12 December 2020
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DNA fragmentation and cytotoxicity from increased cellular deoxyuridylate
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18599024
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12 December 2020
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Deoxyribonucleoside triphosphate imbalance. 5-Fluorodeoxyuridine-induced DNA double strand breaks in mouse FM3A cells and the mechanism of cell death
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18599024
retrieved
12 December 2020
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A specialized form of chromosomal DNA degradation induced by thymidylate stress in mouse FM3A cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18599024
retrieved
12 December 2020
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Fluorodeoxyuridine modulates cellular expression of the DNA base excision repair enzyme uracil-DNA glycosylase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18599024
retrieved
12 December 2020
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Folate Deficiency In Vitro Induces Uracil Misincorporation and DNA Hypomethylation and Inhibits DNA Excision Repair in Immortalized Normal Human Colon Epithelial Cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18599024
retrieved
12 December 2020
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Properties and levels of deoxynucleoside kinases in normal and tumor cells; implications for chemotherapy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18599024
retrieved
12 December 2020
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DNA damage and p53 induction do not cause ZD1694-induced cell cycle arrest in human colon carcinoma cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18599024
retrieved
12 December 2020
based on heuristic
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Identifiers
DOI
10.1016/J.BCP.2008.05.019
1 reference
stated in
Europe PubMed Central
PMC publication ID
2562027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18599024%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
PMC publication ID
2562027
1 reference
stated in
Europe PubMed Central
PMC publication ID
2562027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18599024%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
PubMed publication ID
18599024
1 reference
stated in
Europe PubMed Central
PMC publication ID
2562027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18599024%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
ResearchGate publication ID
5225772
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