(Q36742195)

16 August 2017

A truncated fragment of Src protein kinase generated by calpain-mediated cleavage is a mediator of neuronal death in excitotoxicity (English)

1 reference

16 August 2017

1 reference

Heung-Chin Cheng

13

0 references

Nicholas A. Williamson

object named as

Nicholas A Williamson

8

0 references

Andrew F. Hill

object named as

Andrew F Hill

12

0 references

Carli L Roulston

2

object named as

Carli L Roulston

1 reference

16 August 2017

M Iqbal Hossain

1

1 reference

16 August 2017

M Aizuddin Kamaruddin

3

1 reference

16 August 2017

Percy W Y Chu

4

1 reference

16 August 2017

Dominic C H Ng

5

1 reference

16 August 2017

Gregory J Dusting

6

1 reference

16 August 2017

Jeffrey D Bjorge

7

1 reference

16 August 2017

Donald J Fujita

9

1 reference

16 August 2017

Steve N Cheung

10

1 reference

16 August 2017

Tung O Chan

11

1 reference

16 August 2017

language of work or name

English

0 references

publication date

11 February 2013

1 reference

Journal of Biological Chemistry

16 August 2017

1 reference

16 August 2017

288

1 reference

16 August 2017

14

1 reference

16 August 2017

9696-9709

1 reference

describes a project that uses

16 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3617272/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticity.

29 September 2017

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Phosphoinositide 3-kinase enhancer regulates neuronal dendritogenesis and survival in neocortex

29 September 2017

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Role of calcineurin in neurodegeneration produced by misfolded proteins and endoplasmic reticulum stress

29 September 2017

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Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a ß-arrestin2/Src/Akt signaling complex in vivo

29 September 2017

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Inhibition of TRPC6 degradation suppresses ischemic brain damage in rats

29 September 2017

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29 September 2017

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Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

29 September 2017

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Myristoylation and membrane binding regulate c-Src stability and kinase activity

29 September 2017

1 reference

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Blood-brain barrier breakdown and repair by Src after thrombin-induced injury

29 September 2017

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DAPK1 interaction with NMDA receptor NR2B subunits mediates brain damage in stroke

29 September 2017

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Electrical stimulation of the cerebral cortex exerts antiapoptotic, angiogenic, and anti-inflammatory effects in ischemic stroke rats through phosphoinositide 3-kinase/Akt signaling pathway

29 September 2017

1 reference

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Thyroid-hormone-dependent activation of the phosphoinositide 3-kinase/Akt cascade requires Src and enhances neuronal survival

29 September 2017

1 reference

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Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP

29 September 2017

1 reference

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Neuroprotective strategies targeting apoptotic and necrotic cell death for stroke

29 September 2017

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Cellular interplay between neurons and glia: toward a comprehensive mechanism for excitotoxic neuronal loss in neurodegeneration

29 September 2017

1 reference

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Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration

29 September 2017

1 reference

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NMDA receptors in clinical neurology: excitatory times ahead

29 September 2017

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A new penumbra: transitioning from injury into repair after stroke

29 September 2017

1 reference

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Src kinase inhibition decreases thrombin-induced injury and cell cycle re-entry in striatal neurons

29 September 2017

1 reference

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Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death

29 September 2017

1 reference

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Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis

29 September 2017

1 reference

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Newest findings on the oldest oncogene; how activated src does it

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Tyrosine 981, a novel ret autophosphorylation site, binds c-Src to mediate neuronal survival

29 September 2017

1 reference

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Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Akt as a mediator of cell death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Interaction between Src and a C-terminal proline-rich motif of Akt is required for Akt activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Calpain-dependent cleavage of cain/cabin1 activates calcineurin to mediate calcium-triggered cell death

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Selected glimpses into the activation and function of Src kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

The cytoskeleton of digitonin-treated rat hepatocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Potential positive and negative autoregulation of p60c-src by intermolecular autophosphorylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Cortical evoked potential and extracellular K+ and H+ at critical levels of brain ischemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Purification and enzymatic characterization of pp60c-src from human platelets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Apoptosis induced by SRC-family tyrosine kinase inhibitors in cultured rat cortical cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Neuroprotective profile of novel SRC kinase inhibitors in rodent models of cerebral ischemia

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

The endogenous inhibitor of Akt, CTMP, is critical to ischemia-induced neuronal death

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Physiological and pathological actions of calpains in glutamatergic neurons

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Activated Src kinases interact with the N-methyl-D-aspartate receptor after neonatal brain ischemia.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Using behaviour to predict stroke severity in conscious rats: post-stroke treatment with 3', 4'-dihydroxyflavonol improves recovery.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Novel pyrazolo[1,5-a]pyrimidines as c-Src kinase inhibitors that reduce IKr channel blockade

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Regulation of c-Src activity in glutamate-induced neurodegeneration

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

PP2, a potent inhibitor of Src family kinases, protects against hippocampal CA1 pyramidal cell death after transient global brain ischemia

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

SRC kinase inhibition improves acute outcomes after experimental intracerebral hemorrhage

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Calpain-mediated mGluR1alpha truncation: a key step in excitotoxicity

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

RhoB and actin polymerization coordinate Src activation with endosome-mediated delivery to the membrane

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Src family kinase-inhibitor PP2 reduces focal ischemic brain injury

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Selective release of calpain produced alphalI-spectrin (alpha-fodrin) breakdown products by acute neuronal cell death

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617272

Thresholds in cerebral ischemia - the ischemic penumbra

5 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23400779

12 December 2020

Sequential detergent fractionation of primary neurons for proteomics studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/23400779

12 December 2020

Brain protection: maybe yes, maybe no

1 reference

https://pubmed.ncbi.nlm.nih.gov/23400779

12 December 2020

Perivascular microapplication of endothelin-1: a new model of focal cerebral ischaemia in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/23400779

12 December 2020

Identifiers

DOI

10.1074/JBC.M112.419713

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

23400779

1 reference