(Q36637905)

15 August 2017

1 reference

title

Nuclear factor-kappaB and inhibitor of kappaB kinase pathways in oncogenic initiation and progression (English)

1 reference

15 August 2017

Bassères DS

1

1 reference

15 August 2017

Baldwin AS

series ordinal

2

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15 August 2017

language of work or name

English

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publication date

1 October 2006

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15 August 2017

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15 August 2017

volume

25

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15 August 2017

issue

51

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15 August 2017

page(s)

6817-6830

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IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf.

15 August 2017

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Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: molecular basis and biological significance

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Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B.

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Phosphorylated FADD induces NF-kappaB, perturbs cell cycle, and is associated with poor outcome in lung adenocarcinomas

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The NF-kappaB pathway blockade by the IKK inhibitor PS1145 can overcome imatinib resistance

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7 January 2021

At the crossroads of inflammation and cancer

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7 January 2021

Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3

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7 January 2021

Mutations in the NF-kappaB signaling pathway: implications for human disease

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7 January 2021

Inflammation and cancer

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NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.

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7 January 2021

A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells

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PI 3-kinase, Akt and cell survival

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7 January 2021

Current insights into the regulation of programmed cell death by NF-kappaB.

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7 January 2021

Inducible IkappaB kinase/IkappaB kinase epsilon expression is induced by CK2 and promotes aberrant nuclear factor-kappaB activation in breast cancer cells

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7 January 2021

Apoptosis induction by a novel retinoid-related molecule requires nuclear factor-kappaB activation.

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7 January 2021

Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications.

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7 January 2021

Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis

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7 January 2021

Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation

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7 January 2021

Targeting NF-kappaB activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells.

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7 January 2021

The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers

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7 January 2021

Modulation of NF-kappa B activity and apoptosis in chronic lymphocytic leukemia B cells

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7 January 2021

Role of inflammation in pancreatic carcinogenesis and the implications for future therapy

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7 January 2021

Inhibition of NF-kappaB activity by BAY 11-7082 increases apoptosis in multidrug resistant leukemic T-cell lines

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7 January 2021

Introduction to NF-kappaB: players, pathways, perspectives

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7 January 2021

Inhibitors of NF-kappaB signaling: 785 and counting

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7 January 2021

PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways

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7 January 2021

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

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7 January 2021

Cell type-specific expression of the IkappaB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-kappa B activation

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7 January 2021

The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells

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7 January 2021

Lymphocyte transformation by Pim-2 is dependent on nuclear factor-kappaB activation

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7 January 2021

The Hallmarks of Cancer

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7 January 2021

The nuclear factor kappaB subunits RelA/p65 and c-Rel potentiate but are not required for Ras-induced cellular transformation.

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7 January 2021

Signaling to NF-kappaB

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7 January 2021

The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation

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7 January 2021

Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells.

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7 January 2021

Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses

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7 January 2021

Nuclear factor-kappaB induced by doxorubicin is deficient in phosphorylation and acetylation and represses nuclear factor-kappaB-dependent transcription in cancer cells

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7 January 2021

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

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7 January 2021

Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma

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7 January 2021

Epithelial-mesenchymal transition: NF-kappaB takes center stage

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7 January 2021

Inhibition of anchorage-independent growth and lung metastasis of A549 lung carcinoma cells by IkappaBbeta

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7 January 2021

Activation of nuclear factor-kappaB contributes to induction of death receptors and apoptosis by the synthetic retinoid CD437 in DU145 human prostate cancer cells.

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7 January 2021

IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis

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7 January 2021

Transcription factor cross-talk: the estrogen receptor and NF-kappaB.

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7 January 2021

Nuclear factor-kappaB in cancer development and progression

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7 January 2021

NF-kappaB in cancer: from innocent bystander to major culprit

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7 January 2021

Expression of the Bcl-3 proto-oncogene suppresses p53 activation

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7 January 2021

Inhibition of NF-kappa B activity by thalidomide through suppression of IkappaB kinase activity

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7 January 2021

NF-kappaB and IKK as therapeutic targets in cancer

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7 January 2021

Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes

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7 January 2021

Susceptibility of cholangiocarcinoma cells to parthenolide-induced apoptosis

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7 January 2021

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7 January 2021

Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells.

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7 January 2021

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

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7 January 2021

To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis

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7 January 2021

Mitochondrial-mediated disregulation of Ca2+ is a critical determinant of Velcade (PS-341/bortezomib) cytotoxicity in myeloma cell lines

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7 January 2021

Mitogenic and antiapoptotic role of constitutive NF-kappaB/Rel activity in pancreatic cancer

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7 January 2021

IKK/NF-kappaB signaling: balancing life and death--a new approach to cancer therapy

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7 January 2021

IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

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7 January 2021

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

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7 January 2021

Inhibition of NF-kappaB essentially contributes to arsenic-induced apoptosis.

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7 January 2021

Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.

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7 January 2021

Molecular sequelae of proteasome inhibition in human multiple myeloma cells

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7 January 2021

Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications

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7 January 2021

The chemokine RANTES is secreted by human melanoma cells and is associated with enhanced tumour formation in nude mice.

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7 January 2021

Increased expression of the E3-ubiquitin ligase receptor subunit betaTRCP1 relates to constitutive nuclear factor-kappaB activation and chemoresistance in pancreatic carcinoma cells

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7 January 2021

Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta

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7 January 2021

Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines

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7 January 2021

Constitutive NF-κB/Rel Activation in Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia (ALL)

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7 January 2021

Stat3 activation of NF-{kappa}B p100 processing involves CBP/p300-mediated acetylation

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7 January 2021

Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs

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7 January 2021

Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

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7 January 2021

Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase.

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7 January 2021

Efficacy and mechanism of action of the proteasome inhibitor PS-341 in T-cell lymphomas and HTLV-I associated adult T-cell leukemia/lymphoma

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7 January 2021

MEK kinase 1 mediates the antiapoptotic effect of the Bcr-Abl oncogene through NF-κB activation

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7 January 2021

A loss-of-function RNA interference screen for molecular targets in cancer

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7 January 2021

Analysis of expression of nuclear factor kappa B (NF-kappa B) in multiple myeloma: downregulation of NF-kappa B induces apoptosis

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7 January 2021

Identification of an autoregulatory feedback pathway involving interleukin-1alpha in induction of constitutive NF-kappaB activation in pancreatic cancer cells

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7 January 2021

NF-kappaB as a therapeutic target in cancer

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7 January 2021

Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells

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7 January 2021

NF-kappaB: tumor promoter or suppressor?

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7 January 2021

Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway

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7 January 2021

Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN.

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7 January 2021

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

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7 January 2021

Thalidomide in newly diagnosed multiple myeloma and overview of experience in smoldering/indolent disease

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7 January 2021

DNA microarrays in breast cancer: the promise of personalised medicine

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7 January 2021

Aberrant rel/nfkb genes and activity in human cancer

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7 January 2021

A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation

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7 January 2021

Proteasome inhibition in hematologic malignancies

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7 January 2021

In vitro and in vivo activity of the nuclear factor-kappaB inhibitor sulfasalazine in human glioblastomas

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7 January 2021

Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor

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7 January 2021

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

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7 January 2021

Mouse mammary tumor virus c-rel transgenic mice develop mammary tumors

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7 January 2021

Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-kappaB.

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7 January 2021

Role of NF-κB in p53-mediated programmed cell death

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7 January 2021

Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

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7 January 2021

IkappaB kinase complexes: gateways to NF-kappaB activation and transcription

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7 January 2021

GADD45alpha is highly expressed in pancreatic ductal adenocarcinoma cells and required for tumor cell viability.

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7 January 2021

Nuclear factor-kappaB: a friend or a foe in cancer?

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7 January 2021

Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma

1 reference

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7 January 2021

Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis

1 reference

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7 January 2021

Expression of interleukin-8 in primary and metastatic malignant melanoma of the skin

1 reference

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7 January 2021

Positive and negative regulation of EAAT2 by NF-kappaB: a role for N-myc in TNFalpha-controlled repression.

1 reference

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7 January 2021

Evidence that mitogen-activated protein kinase phosphatase-1 induction by proteasome inhibitors plays an antiapoptotic role

1 reference

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7 January 2021

Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis

1 reference

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7 January 2021

Nucleolar sequestration of RelA (p65) regulates NF-kappaB-driven transcription and apoptosis

1 reference

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7 January 2021

Anti-proliferative and apoptotic effects of celecoxib on human chronic myeloid leukemia in vitro

1 reference

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7 January 2021

Human anti-CD40 antagonist antibody triggers significant antitumor activity against human multiple myeloma

1 reference

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7 January 2021

Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation

1 reference

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7 January 2021

A novel NF-kappaB inhibitor, IMD-0354, suppresses neoplastic proliferation of human mast cells with constitutively activated c-kit receptors

1 reference

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7 January 2021

p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapy

1 reference

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7 January 2021

Epithelial-mesenchymal transitions in tumour progression

1 reference

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7 January 2021

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

1 reference

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7 January 2021

NF-kappaB activation in melanoma

1 reference

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7 January 2021

Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB

1 reference

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7 January 2021

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

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7 January 2021

Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA

1 reference

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7 January 2021

Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells

1 reference

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7 January 2021

Transcriptional cross talk between NF-kappaB and p53.

1 reference

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7 January 2021

The putative oncoprotein Bcl-3 induces cyclin D1 to stimulate G(1) transition

1 reference

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7 January 2021

Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer

1 reference

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7 January 2021

Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM).

1 reference

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7 January 2021

Cytokine modulation of nuclear factor-kappaB activity in B-chronic lymphocytic leukemia.

1 reference

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7 January 2021

NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK.

1 reference

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7 January 2021

Constitutive NF-kappaB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity

1 reference

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7 January 2021

The NFkappaB pathway and endocrine-resistant breast cancer

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209942

1 reference

Dimensions Publication ID

15 August 2017

1028771627

0 references

1 reference