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The carboxy-terminal transactivation domain of Oct-4 acquires cell specificity through the POU domain.
scientific article published on January 1997
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Europe PubMed Central
PMC publication ID
231739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8972195%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
title
The carboxy-terminal transactivation domain of Oct-4 acquires cell specificity through the POU domain
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
231739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8972195%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
author
Hans Schöler
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
231739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8972195%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
author name string
A Brehm
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
231739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8972195%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
K Ohbo
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
231739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8972195%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
language of work or name
English
0 references
publication date
1 January 1997
1 reference
stated in
Europe PubMed Central
PMC publication ID
231739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8972195%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
published in
Molecular and Cellular Biology
1 reference
stated in
Europe PubMed Central
PMC publication ID
231739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8972195%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
volume
17
1 reference
stated in
Europe PubMed Central
PMC publication ID
231739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8972195%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
issue
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
231739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8972195%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
page(s)
154-162
1 reference
stated in
Europe PubMed Central
PMC publication ID
231739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8972195%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
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Retinoic acid-mediated down-regulation of Oct3/4 coincides with the loss of promoter occupancy in vivo
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Regulation of JC virus by the POU-domain transcription factor Tst-1: implications for progressive multifocal leukoencephalopathy
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Differential transactivation potential of Oct1 and Oct2 is determined by additional B cell-specific activities
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Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules
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Reconstitution of transcriptional activation domains by reiteration of short peptide segments reveals the modular organization of a glutamine-rich activation domain
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The Oct-2 glutamine-rich and proline-rich activation domains can synergize with each other or duplicates of themselves to activate transcription
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Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation
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30 September 2017
Functional differences between the Oct2 transactivation domains determine the transactivation potential of individual Oct2 isoforms
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30 September 2017
OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins
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Functional interaction between the POU domain protein Tst-1/Oct-6 and the high-mobility-group protein HMG-I/Y
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A B-cell coactivator of octamer-binding transcription factors
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ATF-2 contains a phosphorylation-dependent transcriptional activation domain
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30 September 2017
High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors
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Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B
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The POU domain: versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain.
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Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3
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A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factor
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Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells
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Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylation
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Control of c-Jun activity by interaction of a cell-specific inhibitor with regulatory domain delta: differences between v- and c-Jun
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A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo
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30 September 2017
Stringent integrity requirements for both trans-activation and DNA-binding in a trans-activator, Oct3
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30 September 2017
Both Oct-1 and Oct-2A contain domains which can activate the ubiquitously expressed U2 snRNA genes
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Octamania: The POU factors in murine development
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30 September 2017
Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoter
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30 September 2017
New type of POU domain in germ line-specific protein Oct-4
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30 September 2017
The cell-type-specific activator region of c-Jun juxtaposes constitutive and negatively regulated domains
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30 September 2017
Oct2 transactivation from a remote enhancer position requires a B-cell-restricted activity
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30 September 2017
A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors
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30 September 2017
Differential positive control by Oct-1 and Oct-2: activation of a transcriptionally silent motif through Oct-1 and VP16 corecruitment
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28 June 2018
Transcriptional activation modulated by homopolymeric glutamine and proline stretches
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28 June 2018
A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype
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28 June 2018
v-Src and EJ Ras alleviate repression of c-Jun by a cell-specific inhibitor
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28 June 2018
A nexus between Oct-4 and E1A: implications for gene regulation in embryonic stem cells
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28 June 2018
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28 June 2018
Variable effects of phosphorylation of Pit-1 dictated by the DNA response elements
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28 June 2018
Down-regulation of the POU transcription factor SCIP is an early event in oligodendrocyte differentiation in vitro.
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28 June 2018
Targeted degradation of c-Fos, but not v-Fos, by a phosphorylation-dependent signal on c-Jun
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28 June 2018
Different activation domains stimulate transcription from remote ('enhancer') and proximal ('promoter') positions
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28 June 2018
Twin of I-POU: a two amino acid difference in the I-POU homeodomain distinguishes an activator from an inhibitor of transcription
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28 June 2018
Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene
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21 September 2018
A human lymphoid- specific transcription factor that activates immunoglobulin genes is a homoeobox protein
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8972195
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Intramolecular inhibition of activating transcription factor-2 function by its DNA-binding domain
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8972195
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8972195
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The POU domain is a bipartite DNA-binding structure
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8972195
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.17.1.154
1 reference
stated in
Europe PubMed Central
PMC publication ID
231739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8972195%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
PMC publication ID
231739
1 reference
stated in
Europe PubMed Central
PMC publication ID
231739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8972195%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
PubMed publication ID
8972195
1 reference
stated in
Europe PubMed Central
PMC publication ID
231739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8972195%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 October 2019
ResearchGate publication ID
14236066
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