(Q36549465)

English

Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis

scientific article published on October 2003

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Bruce Spiegelman

11

object named as

Bruce M Spiegelman

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

10

object named as

C Ronald Kahn

1 reference

Europe PubMed Central

14 August 2017

PMC publication ID

1

object named as

Evan D Rosen

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Rohit N Kulkarni

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Pasha Sarraf

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Umut Ozcan

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Terumasa Okada

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Chung-Hsin Hsu

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Daniel Eisenman

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Frank J Gonzalez

9

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

0 references

publication date

1 October 2003

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

23

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

20

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

7222-7229

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Receptors for insulin and insulin-like growth factor-1 and insulin receptor substrate-1 mediate pathways that regulate islet function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Peroxisomal proliferator-activated receptor-gamma upregulates glucokinase gene expression in beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

A kinase in the life of the beta cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

PPARgamma : a nuclear regulator of metabolism, differentiation, and cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Evidence for a circulating islet cell growth factor in insulin-resistant states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Peroxisome proliferator-activated receptor gamma ligand-induced growth inhibition of human hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Diseases of liporegulation: new perspective on obesity and related disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Identification and functional characterization of the peroxisomal proliferator response element in rat GLUT2 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Genetic differences in endocrine pancreatic tumor subtypes detected by comparative genomic hybridization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

PPAR gamma is required for placental, cardiac, and adipose tissue development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Troglitazone prevents mitochondrial alterations, beta cell destruction, and diabetes in obese prediabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Role of peroxisome proliferator-activated receptor alpha in disease of pancreatic beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

A novel pancreatic endocrine tumor suppressor gene locus on chromosome 3p with clinical prognostic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

30 September 2017

Terminal differentiation of human breast cancer through PPAR gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

28 June 2018

Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

28 June 2018

Effect of troglitazone on insulin sensitivity and pancreatic beta-cell function in women at high risk for NIDDM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

28 June 2018

Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

21 September 2018

beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

21 September 2018

Rosiglitazone (BRL 49653) enhances insulin secretory response via phosphatidylinositol 3-kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

21 September 2018

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

21 September 2018

Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta -cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

21 September 2018

Analysis of the Cre-mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

21 September 2018

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

21 September 2018

Localization of putative tumor suppressor loci by genome-wide allelotyping in human pancreatic endocrine tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

21 September 2018

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

21 September 2018

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=230305

21 September 2018

Expression of insulin receptor mRNA and insulin receptor substrate 1 in pancreatic islet beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluorescence-activated cell sorted rat islet cells and studies of the insulin secretory process

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation and reversal of malignant changes in colon cancer through PPARgamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent loss of heterozygosity at chromosome 3p14.2-3p21 in human pancreatic islet cell tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss-of-Function Mutations in PPARγ Associated with Human Colon Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of peroxisome proliferator-activated receptor γ (PPARγ) in normal human pancreatic islet cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPARgamma ligand (thiazolidinedione) induces growth arrest and differentiation markers of human pancreatic cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic imbalances in the progression of endocrine pancreatic tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.23.20.7222-7229.2003

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

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