Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q36401482)
Watch
English
The Vav-Rac1 pathway in cytotoxic lymphocytes regulates the generation of cell-mediated killing
scientific article
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
title
The Vav-Rac1 pathway in cytotoxic lymphocytes regulates the generation of cell-mediated killing
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
main subject
cytotoxicity
0 references
lymphocyte
0 references
author
Xosé R. Bustelo
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
author name string
D D Billadeau
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
K M Brumbaugh
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
C J Dick
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
R A Schoon
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
P J Leibson
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
language of work or name
English
0 references
publication date
1 August 1998
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
published in
Journal of Experimental Medicine
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
volume
188
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
page(s)
549-559
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
cites work
Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Rho is required for the initiation of calcium signaling and phagocytosis by Fcgamma receptors in macrophages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
The Vav binding site (Y315) in ZAP-70 is critical for antigen receptor-mediated signal transduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
The VAV family of signal transduction molecules.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Tyrosine phosphorylation of the vav proto-oncogene product links FcepsilonRI to the Rac1-JNK pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Lck regulates Vav activation of members of the Rho family of GTPases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Critical role for the tyrosine kinase Syk in signalling through the high affinity IgE receptor of mast cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Impaired immune responses toward alloantigens and tumor cells but normal thymic selection in mice deficient in the beta2 integrin leukocyte function-associated antigen-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Rho is a negative regulator of human monocyte spreading
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Physical association of the small GTPase Rho with a 68-kDa phosphatidylinositol 4-phosphate 5-kinase in Swiss 3T3 cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Vav in natural killer cells is tyrosine phosphorylated upon cross-linking of Fc gamma RIIIA and is constitutively associated with a serine/threonine kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Rac-1 dependent stimulation of the JNK/SAPK signaling pathway by Vav.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
SH3 domain-dependent interaction of the proto-oncogene product Vav with the focal contact protein zyxin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Identification of a phosphatidylinositol 4,5-bisphosphate-binding site in chicken skeletal muscle alpha-actinin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Interactions between the protein-tyrosine kinase ZAP-70, the proto-oncoprotein Vav, and tubulin in Jurkat T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
A role for Rho in Ras transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Single point mutations in the SH2 domain impair the transforming potential of vav and fail to activate proto-vav.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Physical and functional association of p56lck with Fc gamma RIIIA (CD16) in natural killer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Association of the p56lck protein tyrosine kinase with the Fc gamma RIIIA/CD16 complex in human natural killer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Fc gamma RIIIA-mediated signaling involves src-family lck in human natural killer cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Cross-linking of Fc gamma receptor I (Fc gamma RI) and receptor II (Fc gamma RII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72 Syk protein tyrosine kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Spreading of differentiating human monocytes is associated with a major increase in membrane-bound CDC42.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
X-ray structures of isoforms of the actin-binding protein profilin that differ in their affinity for phosphatidylinositol phosphates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Fc receptor stimulation of phosphatidylinositol 3-kinase in natural killer cells is associated with protein kinase C-independent granule release and cell-mediated cytotoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
The protein tyrosine kinase ZAP-70 can associate with the SH2 domain of proto-Vav
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Rho Family GTPases Bind to Phosphoinositide Kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
A functional T-cell receptor signaling pathway is required for p95vav activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Inhibition of selective signaling events in natural killer cells recognizing major histocompatibility complex class I
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Does Vav bind to F‐actin through a CH domain?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Structure of the binding site for inositol phosphates in a PH domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Vaccinia virus expression vector: coexpression of beta-galactosidase provides visual screening of recombinant virus plaques
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Biology of natural killer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Tyrosine phosphorylation provides an early and requisite signal for the activation of natural killer cell cytotoxic function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
The hematopoietically expressed vav proto-oncogene shares homology with the dbl GDP-GTP exchange factor, the bcr gene and a yeast gene (CDC24) involved in cytoskeletal organization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Tyrosine phosphorylation of the vav proto-oncogene product in activated B cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Fc gamma receptor activation induces the tyrosine phosphorylation of both phospholipase C (PLC)-gamma 1 and PLC-gamma 2 in natural killer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Functional ambivalence of the Kp43 (CD94) NK cell-associated surface antigen.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Interaction between lck and syk family tyrosine kinases in Fc gamma receptor-initiated activation of natural killer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
30 September 2017
Views on Vav.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
28 June 2018
Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
28 June 2018
Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
28 June 2018
The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
28 June 2018
An essential role for Rac in Ras transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
28 June 2018
Activation of cytolytic T lymphocyte and natural killer cell function through the T11 sheep erythrocyte binding protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
28 June 2018
Signal transduction during human natural killer cell activation: inositol phosphate generation and regulation by cyclic AMP.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
28 June 2018
ADP-ribosylation of the ras-related, GTP-binding protein RhoA inhibits lymphocyte-mediated cytotoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
28 June 2018
Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
28 June 2018
Stimulation of Fc gamma RIIIA results in phospholipase C-gamma 1 tyrosine phosphorylation and p56lck activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
28 June 2018
The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
21 September 2018
Association of a 70-kDa tyrosine phosphoprotein with the CD16:ζ:γ complex expressed in human natural killer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212464
retrieved
5 December 2018
A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9687532
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Selective control of membrane ruffling and actin plaque assembly by the Rho GTPases Rac1 and CDC42 in FcepsilonRI-activated rat basophilic leukemia (RBL-2H3) cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9687532
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Antibody 3G8, specific for the human neutrophil Fc receptor, reacts with natural killer cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9687532
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Defective natural killer cytotoxicity and polymorphonuclear leukocyte antibody-dependent cellular cytotoxicity in patients with LFA-1/OKM-1 deficiency
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9687532
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Phosphoinositide breakdown and evidence for protein kinase C involvement during human NK killing
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9687532
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A role for protein tyrosine kinase activity in natural cytotoxicity as well as antibody-dependent cellular cytotoxicity. Effects of herbimycin A
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9687532
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Stimulation of macrophage Fc gamma RIIIA activates the receptor-associated protein tyrosine kinase Syk and induces phosphorylation of multiple proteins including p95Vav and p62/GAP-associated protein
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9687532
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Triggering of human natural killer cells through CD16 induces tyrosine phosphorylation of the p72syk kinase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9687532
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Tyrosine phosphorylation of the Fc gamma RIII(CD16): zeta complex in human natural killer cells. Induction by antibody-dependent cytotoxicity but not by natural killing
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9687532
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Role of Rho in chemoattractant-activated leukocyte adhesion through integrins
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9687532
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Clonotypic differences in signaling from CD94 (kp43) on NK cells lead to divergent cellular responses
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9687532
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9687532
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1084/JEM.188.3.549
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
PMC publication ID
2212464
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
PubMed publication ID
9687532
1 reference
stated in
Europe PubMed Central
PMC publication ID
2212464
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9687532%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 November 2019
ResearchGate publication ID
13596754
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit