(Q36161258)

12 August 2017

The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability (English)

1 reference

12 August 2017

7

Marc Ladanyi

1 reference

12 August 2017

8

Richard Gorlick

1 reference

12 August 2017

Michael Overholtzer

1

1 reference

12 August 2017

Pulivarthi H Rao

2

1 reference

12 August 2017

Reyna Favis

3

1 reference

12 August 2017

Xin-Yan Lu

4

1 reference

12 August 2017

Michael B Elowitz

5

1 reference

12 August 2017

Francis Barany

6

1 reference

12 August 2017

Arnold J Levine

9

1 reference

12 August 2017

language of work or name

English

0 references

publication date

12 September 2003

1 reference

12 August 2017

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

12 August 2017

100

1 reference

12 August 2017

20

1 reference

12 August 2017

11547-11552

1 reference

DNA substrate dependence of p53-mediated regulation of double-strand break repair

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

The INK4a/ARF network in tumour suppression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Molecular cytogenetic characterization of head and neck squamous cell carcinoma and refinement of 3q amplification

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

2 October 2017

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Genomic alterations associated with loss of heterozygosity for TP53 in Li-Fraumeni syndrome fibroblasts

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Chromosomal regions involved in the pathogenesis of osteosarcomas.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Mutation detection in K-ras, BRCA1, BRCA2, and p53 using PCR/LDR and a universal DNA microarray.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Homologous and nonhomologous recombination resulting in deletion: effects of p53 status, microhomology, and repetitive DNA length and orientation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Analysis of p53-regulated gene expression patterns using oligonucleotide arrays

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Comparative genomic hybridisation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Dissociation of p53-mediated suppression of homologous recombination from G1/S cell cycle checkpoint control

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

The MDM2 gene amplification database

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

p53, the cellular gatekeeper for growth and division

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

A molecular and epidemiological study on bladder cancer: p53 mutations, tobacco smoking, and occupational exposure to asbestos

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

2 October 2017

p53: puzzle and paradigm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Cell type-specific inhibition of p53-mediated apoptosis by mdm2.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

p53 and the Li-Fraumeni syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

MDM2 overexpression is rare in ovarian carcinoma irrespective of TP53 mutation status.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

The p53 tumour suppressor gene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

p53 mutations in human cancers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Amplification of a gene encoding a p53-associated protein in human sarcomas

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Loss of wild-type p53 function is responsible for upregulated homologous recombination in immortal rodent fibroblasts.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Progression in transitional cell carcinoma of the urinary bladder--analysis of Tp53 gene mutations by temperature gradients and sequence in tumor tissues and in cellular urine sediments.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Heterogeneity studies identify a subset of sporadic colorectal cancers without evidence for chromosomal or microsatellite instability.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

Cerebrovascular pathology in Alzheimer's disease and leukoaraiosis.

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1934852100

Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208795

p53 mutational spectra are different between squamous-cell carcinomas of the lip and the oral cavity

21 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

The use of real-time quantitative polymerase chain reaction and comparative genomic hybridization to identify amplification of the REL gene in follicular lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

The p53 functional circuit

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

Allelic imbalances in human bladder cancer: genome-wide detection with high-density single-nucleotide polymorphism arrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

Mutational spectra and immunohistochemical analyses of p53 in human cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

Mutation spectrum of the p53 gene in bone and soft tissue sarcomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

Enhanced proliferative potential in culture of cells from p53-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

Malignant tumors of the osteogenic matrix

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

Novel approach to quantitative polymerase chain reaction using real-time detection: application to the detection of gene amplification in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

DNA sequence copy number increase at 8q: a potential new prognostic marker in high-grade osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

Dissociation of the recombination control and the sequence-specific transactivation function of P53

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

p53 abnormalities and genomic instability in primary human breast carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

Gains and losses of DNA sequences in osteosarcomas by comparative genomic hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

p53 point mutation and survival in colorectal cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

Genomic instability and apoptosis are frequent in p53 deficient young mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12972634

12 December 2020

Identifiers

DOI

10.1073/PNAS.1934852100

1 reference

12 August 2017

0 references

1 reference

12 August 2017

PubMed publication ID

12972634

1 reference