(Q36023747)

11 August 2017

A model for the role of integrins in flow induced mechanotransduction in osteocytes (English)

1 reference

11 August 2017

1 reference

4

Sheldon Weinbaum

1 reference

11 August 2017

2

Laoise M McNamara

1 reference

11 August 2017

Yilin Wang

1

1 reference

11 August 2017

Mitchell B Schaffler

series ordinal

3

1 reference

11 August 2017

language of work or name

English

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publication date

25 September 2007

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11 August 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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11 August 2017

104

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11 August 2017

40

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11 August 2017

15941-15946

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Oscillating fluid flow activation of gap junction hemichannels induces ATP release from MLO-Y4 osteocytes.

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

AlphaVbeta3 integrin ligands enhance volume-sensitive calcium influx in mechanically stretched osteocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Complex functional interaction between integrin receptors and ion channels

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Cellular mechanotransduction: putting all the pieces together again

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Integrin receptor activation triggers converging regulation of Cav1.2 calcium channels by c-Src and protein kinase A pathways

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

The P2X7 nucleotide receptor mediates skeletal mechanotransduction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Mechanotransduction and strain amplification in osteocyte cell processes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Estimating the sensitivity of mechanosensitive ion channels to membrane strain and tension

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Pannexin membrane channels are mechanosensitive conduits for ATP

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Integrins in mechanotransduction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Fluid flow induced PGE2 release by bone cells is reduced by glycocalyx degradation whereas calcium signals are not

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Quantitative Analysis of Platelet αvβ3 Binding to Osteopontin Using Laser Tweezers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Mechanotransduction and flow across the endothelial glycocalyx

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Bone matrix proteins: their function, regulation, and relationship to osteoporosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Protein–protein unbinding induced by force: single-molecule studies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Force measurements of the alpha5beta1 integrin-fibronectin interaction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Integrins: bidirectional, allosteric signaling machines

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

An atomic model of actin filaments cross-linked by fimbrin and its implications for bundle assembly and function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Parathyroid hormone enhances fluid shear-induced [Ca2+]i signaling in osteoblastic cells through activation of mechanosensitive and voltage-sensitive Ca2+ channels

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Mechanotransduction in bone--role of the lacuno-canalicular network

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Reconstitution of stretch-activated cation channels by expression of the alpha-subunit of the epithelial sodium channel cloned from osteoblasts

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Antisense oligodeoxynucleotide inhibition of a swelling-activated cation channel in osteoblast-like osteosarcoma cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Localization of CD44, the hyaluronate receptor, on the plasma membrane of osteocytes and osteoclasts in rat tibiae

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Candidates for the mechanosensory system in bone

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Regulation of the L-type calcium channel by alpha 5beta 1 integrin requires signaling between focal adhesion proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Induction of NO and prostaglandin E2 in osteoblasts by wall-shear stress but not mechanical strain

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Involvement of different ion channels in osteoblasts' and osteocytes' early responses to mechanical strain

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Functional organization of the cytoskeleton

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

An electron microscopic study on the presence of proteoglycans in the mineralized matrix of rat and human compact lamellar bone

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Ultrastructure of the osteocyte process and its pericellular matrix

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Beta1-integrins co-localize with Na, K-ATPase, epithelial sodium channels (ENaC) and voltage activated calcium channels (VACC) in mechanoreceptor complexes of mouse limb-bud chondrocytes.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

L-type calcium channels mediate mechanically induced bone formation in vivo

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Regulation of free Ca2+ concentration in hair-cell stereocilia.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Chronic, intermittent loading alters mechanosensitive channel characteristics in osteoblast-like cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000405

Single integrin molecule adhesion forces in intact cells measured by atomic force microscopy

23 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/17895377

12 December 2020

Regulation of bone formation by applied dynamic loads

1 reference

https://pubmed.ncbi.nlm.nih.gov/17895377

12 December 2020

Regulation of bone mass by mechanical strain magnitude

1 reference

https://pubmed.ncbi.nlm.nih.gov/17895377

12 December 2020

Low mechanical signals strengthen long bones

1 reference

https://pubmed.ncbi.nlm.nih.gov/17895377

12 December 2020

Parathyroid hormone-activated volume-sensitive calcium influx pathways in mechanically loaded osteocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17895377

12 December 2020

Quantifying the strain history of bone: spatial uniformity and self-similarity of low-magnitude strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/17895377

12 December 2020

A model for strain amplification in the actin cytoskeleton of osteocytes due to fluid drag on pericellular matrix

1 reference

https://pubmed.ncbi.nlm.nih.gov/17895377

12 December 2020

A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses

1 reference

https://pubmed.ncbi.nlm.nih.gov/17895377

12 December 2020

A fiber matrix model for fluid flow and streaming potentials in the canaliculi of an osteon

1 reference

https://pubmed.ncbi.nlm.nih.gov/17895377

12 December 2020

Identifiers

DOI

10.1073/PNAS.0707246104

1 reference

11 August 2017

0 references

1 reference

11 August 2017

PubMed publication ID

17895377

1 reference