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The herpes simplex virus type 1 latency-associated transcript gene regulates the establishment of latency
scientific article published in July 1997
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
191783
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188615%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
title
The herpes simplex virus type 1 latency-associated transcript gene regulates the establishment of latency
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
191783
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188615%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
main subject
Herpes simplex virus type 1
1 reference
based on heuristic
inferred from title
author name string
R L Thompson
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
191783
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188615%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
N M Sawtell
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
191783
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188615%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
language of work or name
English
0 references
publication date
1 July 1997
1 reference
stated in
Europe PubMed Central
PMC publication ID
191783
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188615%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
published in
Journal of Virology
1 reference
stated in
Europe PubMed Central
PMC publication ID
191783
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188615%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
volume
71
1 reference
stated in
Europe PubMed Central
PMC publication ID
191783
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188615%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
issue
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
191783
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188615%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
page(s)
5432-5440
1 reference
stated in
Europe PubMed Central
PMC publication ID
191783
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188615%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
cites work
Comprehensive quantification of herpes simplex virus latency at the single-cell level
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Analysis of the 2-kilobase latency-associated transcript expressed in PC12 cells productively infected with herpes simplex virus type 1: evidence for a stable, nonlinear structure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
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11 July 2018
Correlation between herpes simplex virus type 1 rate of reactivation from latent infection and the number of infected neurons in trigeminal ganglia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
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11 July 2018
Evidence that two latency-associated transcripts of herpes simplex virus type 1 are nonlinear
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
A 348-base-pair region in the latency-associated transcript facilitates herpes simplex virus type 1 reactivation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Quantitation of herpes simplex virus type 1 DNA and latency-associated transcripts in rabbit trigeminal ganglia demonstrates a stable reservoir of viral nucleic acids during latency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
A 371-nucleotide region between the herpes simplex virus type 1 (HSV-1) LAT promoter and the 2-kilobase LAT is not essential for efficient spontaneous reactivation of latent HSV-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
The spontaneous reactivation function of the herpes simplex virus type 1 LAT gene resides completely within the first 1.5 kilobases of the 8.3-kilobase primary transcript
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Evidence for a novel regulatory pathway for herpes simplex virus gene expression in trigeminal ganglion neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
An HSV LAT null mutant reactivates slowly from latent infection and makes small plaques on CV-1 monolayers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
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11 July 2018
Herpes simplex virus type 1 DNA replication and gene expression during explant-induced reactivation of latently infected murine sensory ganglia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
The latency-associated transcript gene of herpes simplex virus type 1 (HSV-1) is required for efficient in vivo spontaneous reactivation of HSV-1 from latency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Quantification of transcripts from the ICP4 and thymidine kinase genes in mouse ganglia latently infected with herpes simplex virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Expression of a putative ATPase suppresses the growth defect of a yeast potassium transport mutant: identification of a mammalian member of the Clp/HSP104 family.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Two herpes simplex virus type 1 latency-active promoters differ in their contributions to latency-associated transcript expression during lytic and latent infections
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
RNA from an immediate early region of the type 1 herpes simplex virus genome is present in the trigeminal ganglia of latently infected mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
The herpes simplex virus latency-associated transcript is spliced during the latent phase of infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
The DNA sequences of the long repeat region and adjoining parts of the long unique region in the genome of herpes simplex virus type 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Fine mapping of the latency-related gene of herpes simplex virus type 1: alternative splicing produces distinct latency-related RNAs containing open reading frames
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Expression of herpes simplex virus type 1 latency-associated transcripts in the trigeminal ganglia of mice during acute infection and reactivation of latent infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Physical characterization of the herpes simplex virus latency-associated transcript in neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Herpes simplex latent infection: quantitation of latency-associated transcript-positive neurons and reactivable neurons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Herpes simplex virus neurovirulence and productive infection of neural cells is associated with a function which maps between 0.82 and 0.832 map units on the HSV genome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Quantitative polymerase chain reaction analysis of herpes simplex virus DNA in ganglia of mice infected with replication-incompetent mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Mapping of low abundance latency-associated RNA in the trigeminal ganglia of mice latently infected with herpes simplex virus type 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Herpes simplex virus latent phase transcription facilitates in vivo reactivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Herpes simplex virus latency-associated transcript is a stable intron
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
In vivo and in vitro reactivation impairment of a herpes simplex virus type 1 latency-associated transcript variant in a rabbit eye model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Identification of a novel latency-specific splice donor signal within the herpes simplex virus type 1 2.0-kilobase latency-associated transcript (LAT): translation inhibition of LAT open reading frames by the intron within the 2.0-kilobase LAT
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Peripheral replication and latency reactivation kinetics of the non-neurovirulent herpes simplex virus type 1 variant 1716
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Herpes simplex virus type 1 latency-associated transcription unit promotes anatomical site-dependent establishment and reactivation from latency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Rapid in vivo reactivation of herpes simplex virus in latently infected murine ganglionic neurons after transient hyperthermia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
11 July 2018
Neurons containing latency-associated transcripts are numerous and widespread in dorsal root ganglia following footpad inoculation of mice with herpes simplex virus type 1 mutant in1814.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
24 September 2018
In situ DNA PCR and RNA hybridization detection of herpes simplex virus sequences in trigeminal ganglia of latently infected mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
24 September 2018
A herpes simplex virus ribonucleotide reductase deletion mutant is defective for productive acute and reactivatable latent infections of mice and for replication in mouse cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191783
retrieved
24 September 2018
Latent infection can be established with drastically restricted transcription and replication of the HSV-1 genome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9188615
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
An HSV-1 mutant lacking the LAT TATA element reactivates normally in explant cocultivation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9188615
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
RNA complementary to a herpesvirus alpha gene mRNA is prominent in latently infected neurons
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9188615
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/JVI.71.7.5432-5440.1997
0 references
PMC publication ID
191783
1 reference
stated in
Europe PubMed Central
PMC publication ID
191783
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188615%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
PubMed publication ID
9188615
1 reference
stated in
Europe PubMed Central
PMC publication ID
191783
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188615%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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