(Q35847511)

English

The C-terminal repressor region of herpes simplex virus type 1 ICP27 is required for the redistribution of small nuclear ribonucleoprotein particles and splicing factor SC35; however, these alterations are not sufficient to inhibit host cell splicing

scientific article published on October 1, 1995

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23 October 2019

The C-terminal repressor region of herpes simplex virus type 1 ICP27 is required for the redistribution of small nuclear ribonucleoprotein particles and splicing factor SC35; however, these alterations are not sufficient to inhibit host cell splicing (English)

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23 October 2019

ribonucleoprotein complex

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based on heuristic

inferred from title

Herpes simplex virus type 1

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based on heuristic

inferred from title

immediate-early proteins

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1 August 2024

DNA replication

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1 August 2024

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R. M. Sandri-Goldin

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1 August 2024

M. K. Hibbard

2

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1 August 2024

M. A. Hardwicke

3

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1 August 2024

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1 October 1995

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23 October 2019

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https://jvi.asm.org/content/jvi/69/10/6063.full.pdf

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1 August 2024

http://jvi.asm.org/cgi/content/abstract/69/10/6063

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1 August 2024

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1 August 2024

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1 August 2024

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1 August 2024

https://journals.asm.org/doi/pdf/10.1128/jvi.69.10.6063-6076.1995

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10.1128/JVI.69.10.6063-6076.1995

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1 August 2024

Journal of Virology

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23 October 2019

69

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23 October 2019

10

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23 October 2019

6063-6076

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23 October 2019

A three-dimensional view of precursor messenger RNA metabolism within the mammalian nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

A herpes simplex virus type 1 immediate-early gene product, IE63, regulates small nuclear ribonucleoprotein distribution.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Nuclear organization of splicing small nuclear ribonucleoproteins in adenovirus-infected cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Specific commitment of different pre-mRNAs to splicing by single SR proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Cooperativity among herpes simplex virus type 1 immediate-early regulatory proteins: ICP4 and ICP27 affect the intracellular localization of ICP0

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Intracellular localization of the herpes simplex virus type 1 major transcriptional regulatory protein, ICP4, is affected by ICP27

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Evaluation of colocalization interactions between the IE110, IE175, and IE63 transactivator proteins of herpes simplex virus within subcellular punctate structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Dynamic organization of splicing factors in adenovirus-infected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Physical interaction between the herpes simplex virus type 1 immediate-early regulatory proteins ICP0 and ICP4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Herpes simplex virus inhibits host cell splicing, and regulatory protein ICP27 is required for this effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Assembly and disassembly of spliceosomes along a specific pre-messenger RNP fiber.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

The biogenesis of the coiled body during early mouse development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Is the sphere organelle/coiled body a universal nuclear component?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Splicing components are excluded from the transcriptionally inactive XY body in male meiotic nuclei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Arginine-rich regions succeeding the nuclear localization region of the herpes simplex virus type 1 regulatory protein ICP27 are required for efficient nuclear localization and late gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Identification of nuclear and nucleolar localization signals in the herpes simplex virus regulatory protein ICP27.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Expression of herpes simplex virus beta and gamma genes integrated in mammalian cells and their induction by an alpha gene product.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Ultrastructural distribution of nuclear ribonucleoproteins as visualized by immunocytochemistry on thin sections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

A short amino acid sequence able to specify nuclear location

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Characterization of herpes simplex virus 1 alpha proteins 0, 4, and 27 with monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Sequence requirements for nuclear location of simian virus 40 large-T antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Polysomes and protein synthesis in cells infected with a DNA virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism

1 reference

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11 July 2018

Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear events

1 reference

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11 July 2018

Molecular cloning of a cDNA encoding the human Sm-D autoantigen

1 reference

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11 July 2018

Intranuclear localization of snRNP antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Formation of DNA replication structures in herpes virus-infected cells requires a viral DNA binding protein

1 reference

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11 July 2018

The herpes simplex virus type 1 alpha protein ICP27 can act as a trans-repressor or a trans-activator in combination with ICP4 and ICP0.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Redistribution of nuclear ribonucleoprotein antigens during herpes simplex virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

The regions important for the activator and repressor functions of herpes simplex virus type 1 alpha protein ICP27 map to the C-terminal half of the molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Mapping of B cell epitopes on small nuclear ribonucleoproteins that react with human autoantibodies as well as with experimentally-induced mouse monoclonal antibodies

1 reference

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11 July 2018

Sequence-specific recognition of RNA hairpins by bacteriophage antiterminators requires a conserved arginine-rich motif

1 reference

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11 July 2018

The repressing and enhancing functions of the herpes simplex virus regulatory protein ICP27 map to C-terminal regions and are required to modulate viral gene expression very early in infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus

1 reference

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11 July 2018

Higher order nuclear organization: three-dimensional distribution of small nuclear ribonucleoprotein particles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Mutational analysis of the human immunodeficiency virus type 1 Rev transactivator: essential residues near the amino terminus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Analysis of arginine-rich peptides from the HIV Tat protein reveals unusual features of RNA-protein recognition

1 reference

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11 July 2018

In vitro mRNA degradation system to study the virion host shutoff function of herpes simplex virus

1 reference

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11 July 2018

Biochemical Mechanisms of Constitutive and Regulated Pre-mRNA Splicing

1 reference

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11 July 2018

Associations between distinct pre-mRNA splicing components and the cell nucleus

1 reference

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11 July 2018

Localization of pre-messenger RNA at discrete nuclear sites

1 reference

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11 July 2018

Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Nascent pre-mRNA transcripts are associated with nuclear regions enriched in splicing factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Mutations in the activation region of herpes simplex virus regulatory protein ICP27 can be trans dominant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

SR proteins: a conserved family of pre-mRNA splicing factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Transcription-dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

U1 and U2 small nuclear RNAs are present in nuclear speckles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

The herpes simplex virus immediate early protein ICP27 encodes a potential metal binding domain and binds zinc in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

A herpesvirus regulatory protein appears to act post-transcriptionally by affecting mRNA processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Evidence that the herpes simplex virus immediate early protein ICP27 acts post-transcriptionally during infection to regulate gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Localization and characterization of newly synthesized nuclear RNA in isolate rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

11 July 2018

Synthesis and maturation of viral transcripts in herpes simplex virus type 1 infected HeLa cells: the role of interchromatin granules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

24 September 2018

Immunoelectron microscopic localization of snRNPs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

24 September 2018

Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

24 September 2018

Change of processing and nucleocytoplasmic transport of mRNA in HSV-1-infected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189503

24 September 2018

Colocalization of U1 and U2 small nuclear RNPs by immunocytochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/7666511

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Higher level organization of individual gene transcription and RNA splicing

1 reference

https://pubmed.ncbi.nlm.nih.gov/7666511

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of pre-mRNA splicing in mammalian nuclei

1 reference

https://pubmed.ncbi.nlm.nih.gov/7666511

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allotype-specific immunoregulation of autoantibody production by host B cells in chronic graft-versus host disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/7666511

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The coiled body

1 reference

https://pubmed.ncbi.nlm.nih.gov/7666511

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo evidence that transcription and splicing are coordinated by a recruiting mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/7666511

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.69.10.6063-6076.1995

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7666511

1 August 2024

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7666511%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7666511%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

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