(Q35749931)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Using targeted transgenic reporter mice to study promoter-specific p53 transcriptional activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

David P. Lane

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Michael B Mann

5

0 references

author name string

Amanda M Goh

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Poh Cheang Chiam

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Ling Li

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Karen M Mann

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Sergio Menendez

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

17 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

22 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

1685-1690

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

22 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3277193/fullTextXML

inferred from PubMed Central ID database lookup

cites work

p53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Selective activation of p53-mediated tumour suppression in high-grade tumours

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Regulation of tissue- and stimulus-specific cell fate decisions by p53 in vivo.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

A simple procedure for the efficient derivation of mouse ES cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

In vivo analysis of p53 tumor suppressor function using genetically engineered mouse models

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Nuclear accumulation and activation of p53 in embryonic stem cells after DNA damage

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Blinded by the Light: The Growing Complexity of p53

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Targeted transgenesis at the HPRT locus: an efficient strategy to achieve tightly controlled in vivo conditional expression with the tet system

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

A complex barcode underlies the heterogeneous response of p53 to stress

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Acetylation is indispensable for p53 activation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

The pathological response to DNA damage does not contribute to p53-mediated tumour suppression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Suppression of tumorigenesis by the p53 target PUMA

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

The role of p53 in determining sensitivity to radiotherapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Tissue-specific induction of p53 targets in vivo.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Ets1 is required for p53 transcriptional activity in UV-induced apoptosis in embryonic stem cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Tissue specific expression of p53 target genes suggests a key role for KILLER/DR5 in p53-dependent apoptosis in vivo.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

PUMA, a novel proapoptotic gene, is induced by p53

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

PUMA induces the rapid apoptosis of colorectal cancer cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and following ionising irradiation in mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Identification of a novel class of genomic DNA-binding sites suggests a mechanism for selectivity in target gene activation by the tumor suppressor protein p53

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Regulation of ES cell differentiation by functional and conformational modulation of p53.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Single-copy transgenic mice with chosen-site integration

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

27 July 2018

Targeted transgenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

p21 is a universal inhibitor of cyclin kinases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

WAF1, a potential mediator of p53 tumor suppression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Expression of p53 during mouse embryogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277193

Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals

27 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114173109

MDM4 downregulates p53 transcriptional activity and response to stress during differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114173109

Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114173109

Tissue-specific p53 responses to ionizing radiation and their genetic modification: the key to tissue-specific tumour susceptibility?

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114173109

Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114173109

Comparative binding of p53 to its promoter and DNA recognition elements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114173109

p53 coordinates cranial neural crest cell growth and epithelial-mesenchymal transition/delamination processes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114173109

Modeling the therapeutic efficacy of p53 restoration in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114173109

Restoration of p53 function leads to tumour regression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114173109

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114173109

Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114173109

Stage-specific sensitivity to p53 restoration during lung cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114173109

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114173109

Cre-mediated chromosome loss in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114173109

Bioluminescent molecular imaging of endogenous and exogenous p53-mediated transcription in vitro and in vivo using an HCT116 human colon carcinoma xenograft model

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22307631

12 December 2020

Induction of endogenous beta-galactosidase by ionizing radiation complicates the analysis of p53-LacZ transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22307631

12 December 2020

p53 is preferentially recruited to the promoters of growth arrest genes p21 and GADD45 during replicative senescence of normal human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22307631

12 December 2020

Real-time evaluation of p53 oscillatory behavior in vivo using bioluminescent imaging

1 reference

https://pubmed.ncbi.nlm.nih.gov/22307631

12 December 2020

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/22307631

12 December 2020

Identifiers

DOI

10.1073/PNAS.1114173109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

22307631

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22307631%20AND%20SRC:MED&resulttype=core&format=json