(Q35745376)

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Identification of Cholesterol 25-Hydroxylase as a Novel Host Restriction Factor and a Part of the Primary Innate Immune Responses against Hepatitis C Virus Infection

scientific article published on 22 April 2015

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scholarly article

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Europe PubMed Central

PubMed publication ID

10 August 2017

Identification of Cholesterol 25-Hydroxylase as a Novel Host Restriction Factor and a Part of the Primary Innate Immune Responses against Hepatitis C Virus Infection (English)

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Europe PubMed Central

PubMed publication ID

10 August 2017

Hepatitis C virus

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based on heuristic

inferred from title

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based on heuristic

inferred from title

5

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10 June 2020

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Yu Xiang

1

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10 June 2020

Jing-Jie Tang

2

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10 June 2020

Wanyin Tao

3

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10 June 2020

Xuezhi Cao

4

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10 June 2020

Jin Zhong

6

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10 June 2020

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22 April 2015

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10 August 2017

Journal of Virology

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10 June 2020

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10 June 2020

13

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10 June 2020

6805-6816

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10 June 2020

Inhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol.

1 reference

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12 July 2018

Interferon-inducible cholesterol-25-hydroxylase inhibits hepatitis C virus replication via distinct mechanisms

1 reference

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12 July 2018

MDA5 plays a critical role in interferon response during hepatitis C virus infection

1 reference

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12 July 2018

Forward genetic screening for regulators involved in cholesterol synthesis using validation-based insertional mutagenesis

1 reference

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12 July 2018

25-Hydroxycholesterols in innate and adaptive immunity

1 reference

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12 July 2018

HCV genomic RNA activates the NLRP3 inflammasome in human myeloid cells

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Genome-scale CRISPR-Cas9 knockout screening in human cells

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12 July 2018

A novel strategy to develop a robust infectious hepatitis C virus cell culture system directly from a clinical isolate

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12 July 2018

Hepatitis C virus infection activates an innate pathway involving IKK-α in lipogenesis and viral assembly

1 reference

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12 July 2018

Current and future therapies for hepatitis C virus infection

1 reference

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12 July 2018

Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity

1 reference

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12 July 2018

Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol

1 reference

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12 July 2018

The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response

1 reference

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12 July 2018

Systematic identification of type I and type II interferon-induced antiviral factors

1 reference

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12 July 2018

HCV infection induces a unique hepatic innate immune response associated with robust production of type III interferons

1 reference

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12 July 2018

Human subtilase SKI-1/S1P is a master regulator of the HCV Lifecycle and a potential host cell target for developing indirect-acting antiviral agents

1 reference

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12 July 2018

A diverse range of gene products are effectors of the type I interferon antiviral response

1 reference

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12 July 2018

Listeria monocytogenes infection induces prosurvival metabolic signaling in macrophages

1 reference

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12 July 2018

Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques

1 reference

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12 July 2018

Cholesterol 25-hydroxylase production by dendritic cells and macrophages is regulated by type I interferons

1 reference

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12 July 2018

Viral reorganization of the secretory pathway generates distinct organelles for RNA replication

1 reference

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12 July 2018

25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production

1 reference

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12 July 2018

A single point mutation in E2 enhances hepatitis C virus infectivity and alters lipoprotein association of viral particles.

1 reference

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12 July 2018

Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide

1 reference

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12 July 2018

Fatty acid synthase is up-regulated during hepatitis C virus infection and regulates hepatitis C virus entry and production

1 reference

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12 July 2018

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

1 reference

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12 July 2018

Activation of sterol regulatory element-binding protein 1c and fatty acid synthase transcription by hepatitis C virus non-structural protein 2.

1 reference

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12 July 2018

The lipid droplet is an important organelle for hepatitis C virus production

1 reference

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12 July 2018

Hepatitis C Virus Induces Proteolytic Cleavage of Sterol Regulatory Element Binding Proteins and Stimulates Their Phosphorylation via Oxidative Stress

1 reference

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12 July 2018

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig

1 reference

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12 July 2018

Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins

1 reference

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12 July 2018

Inhibition of dsRNA-induced signaling in hepatitis C virus-infected cells by NS3 protease-dependent and -independent mechanisms

1 reference

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12 July 2018

Protein sensors for membrane sterols

1 reference

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12 July 2018

Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity

1 reference

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12 July 2018

Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

1 reference

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12 July 2018

Complete replication of hepatitis C virus in cell culture

1 reference

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12 July 2018

Robust hepatitis C virus infection in vitro

1 reference

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12 July 2018

The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection

1 reference

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12 July 2018

Promotion of microsatellite instability by hepatitis C virus core protein in human non-neoplastic hepatocyte cells.

1 reference

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12 July 2018

Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation

1 reference

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12 July 2018

Hepatitis C virus infection and liver steatosis

1 reference

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12 July 2018

Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes

1 reference

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12 July 2018

Nonlinear partial differential equations and applications: Genomic analysis of the host response to hepatitis C virus infection

1 reference

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12 July 2018

The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus

1 reference

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12 July 2018

Hepatitis C virus and other flaviviridae viruses enter cells via low density lipoprotein receptor

1 reference

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12 July 2018

cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolism

1 reference

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12 July 2018

Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins

1 reference

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12 July 2018

Identification of type I and type II interferon-induced effectors controlling hepatitis C virus replication.

1 reference

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25 September 2018

Hepatitis C virus NS3/4A protease blocks IL-28 production.

1 reference

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25 September 2018

Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge

1 reference

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25 September 2018

Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake

1 reference

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25 September 2018

Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs

1 reference

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25 September 2018

Identifiers

10.1128/JVI.00587-15

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25903345%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25903345%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25903345%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

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