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Silencers, silencing, and heritable transcriptional states
scientific article published on December 1, 1992
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Europe PubMed Central
PMC publication ID
372887
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1480108%20AND%20SRC:MED&resulttype=core&format=json
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20 September 2019
review article
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Europe PubMed Central
title
Silencers, silencing, and heritable transcriptional states
(English)
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Europe PubMed Central
PMC publication ID
372887
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1480108%20AND%20SRC:MED&resulttype=core&format=json
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Europe PubMed Central
PubMed publication ID
1480108
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1480108
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30 September 2022
fungal gene expression regulation
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Europe PubMed Central
PubMed publication ID
1480108
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author name string
P. Laurenson
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1
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Europe PubMed Central
PubMed publication ID
1480108
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1480108
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J. Rine
series ordinal
2
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Europe PubMed Central
PubMed publication ID
1480108
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1480108
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language of work or name
English
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National Center for Biotechnology Information
PubMed publication ID
1480108
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1480108
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publication date
1 December 1992
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Europe PubMed Central
PMC publication ID
372887
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1480108%20AND%20SRC:MED&resulttype=core&format=json
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20 September 2019
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PubMed publication ID
1480108
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Europe PubMed Central
PubMed publication ID
1480108
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https://europepmc.org/articles/PMC372887
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Europe PubMed Central
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Europe PubMed Central
PubMed publication ID
1480108
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1480108
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30 September 2022
https://europepmc.org/articles/PMC372887?pdf=render
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Portable Document Format
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open access
content deliverer
Europe PubMed Central
1 reference
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Europe PubMed Central
PubMed publication ID
1480108
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1480108
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30 September 2022
published in
Microbiological Reviews
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Europe PubMed Central
PMC publication ID
372887
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1480108%20AND%20SRC:MED&resulttype=core&format=json
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20 September 2019
volume
56
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Europe PubMed Central
PMC publication ID
372887
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1480108%20AND%20SRC:MED&resulttype=core&format=json
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20 September 2019
issue
4
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Europe PubMed Central
PMC publication ID
372887
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1480108%20AND%20SRC:MED&resulttype=core&format=json
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20 September 2019
page(s)
543-560
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Europe PubMed Central
PMC publication ID
372887
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1480108%20AND%20SRC:MED&resulttype=core&format=json
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20 September 2019
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Yeast chromosome replication and segregation
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12 July 2018
Cloning and characterization of four SIR genes of Saccharomyces cerevisiae
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12 July 2018
A position effect on the expression of a tRNA gene mediated by the SIR genes in Saccharomyces cerevisiae
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Purification and characterization of an N alpha-acetyltransferase from Saccharomyces cerevisiae.
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Two-dimensional gel electrophoretic method for mapping DNA replicons
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The localization of replication origins on ARS plasmids in S. cerevisiae
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A yeast telomere binding activity binds to two related telomere sequence motifs and is indistinguishable from RAP1.
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ARS binding factor I of the yeast Saccharomyces cerevisiae binds to sequences in telomeric and nontelomeric autonomously replicating sequences
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Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length
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Chromosome III of Saccharomyces cerevisiae: an ordered clone bank, a detailed restriction map and analysis of transcripts suggest the presence of 160 genes
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12 July 2018
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Multiple factors bind the upstream activation sites of the yeast enolase genes ENO1 and ENO2: ABFI protein, like repressor activator protein RAP1, binds cis-acting sequences which modulate repression or activation of transcription
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12 July 2018
Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae
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12 July 2018
Extragenic suppressors of mar2(sir3) mutations in Saccharomyces cerevisiae
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12 July 2018
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12 July 2018
The ABF1 factor is the transcriptional activator of the L2 ribosomal protein genes in Saccharomyces cerevisiae.
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12 July 2018
DNA metabolism gene CDC7 from yeast encodes a serine (threonine) protein kinase
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12 July 2018
Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster
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ARS binding factor 1 binds adjacent to RAP1 at the UASs of the yeast glycolytic genes PGK and PYK1.
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Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML.
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Dependence of position-effect variegation in Drosophila on dose of a gene encoding an unusual zinc-finger protein
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Genetic analysis of histone H4: essential role of lysines subject to reversible acetylation
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Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.
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A single-stranded DNA binding protein from S. cerevisiae specifically recognizes the T-rich strand of the core sequence of ARS elements and discriminates against mutant sequences
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A role for CDC7 in repression of transcription at the silent mating-type locus HMR in Saccharomyces cerevisiae
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A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome
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12 July 2018
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Evidence suggesting that the ARS elements associated with silencers of the yeast mating-type locus HML do not function as chromosomal DNA replication origins
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12 July 2018
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12 July 2018
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
A position effect on the time of replication origin activation in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Parental imprinting of the mouse H19 gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Signal transduction in yeast mating: Receptors, transcription factors, and the kinase connection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Signal transduction during pheromone response in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Nuclear targeting sequences--a consensus?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Opposite imprinting of the mouse Igf2 and Igf2r genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Silencing: the establishment and inheritance of stable, repressed transcription states
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
An origin of DNA replication and a transcription silencer require a common element
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Telomere-proximal DNA in Saccharomyces cerevisiae is refractory to methyltransferase activity in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Fusion of bacterial protoplasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
A suppressor of mating-type locus mutations in Saccharomyces cerevisiae: evidence for and identification of cryptic mating-type loci
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Switching of a mating-type a mutant allele in budding yeast Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Insertion of a genetic marker into the ribosomal DNA of yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Transposable mating type genes in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Isolation and characterisation of a yeast chromosomal replicator
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Isolation of a circular derivative of yeast chromosome III: implications for the mechanism of mating type interconversion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Simple Mendelian inheritance of the reiterated ribosomal DNA of yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Histone gene deficiencies and position–effect variegation in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
12 July 2018
Pedigree analysis of plasmid segregation in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
25 September 2018
Transformation of white locus DNA in drosophila: dosage compensation, zeste interaction, and position effects.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
25 September 2018
A position effect in the control of transcription at yeast mating type loci
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
25 September 2018
Genomic imprinting determines methylation of parental alleles in transgenic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
25 September 2018
A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
25 September 2018
Modifiers of position-effect variegation in the region from 86C to 88B of the Drosophila melanogaster third chromosome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
25 September 2018
The Hawthorne deletion twenty-five years later
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=372887
retrieved
25 September 2018
Parental-specific methylation of an imprinted transgene is established during gametogenesis and progressively changes during embryogenesis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Time of replication of yeast centromeres and telomeres
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Characterization of a “silencer” in yeast: A DNA sequence with properties opposite to those of a transcriptional enhancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The search for the mouse X-chromosome inactivation centre
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Sporulation in mating type homozygotes of Saccharomyces cerevisiae
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Regulation of transcription in expressed and unexpressed mating type cassettes of yeast
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A family of Saccharomyces cerevisiae repetitive autonomously replicating sequences that have very similar genomic environments
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Organization of DNA sequences and replication origins at yeast telomeres
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Meiotic cytology of Saccharomyces cerevisiae in protoplast lysates
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Putting the HO gene to work: practical uses for mating-type switching
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Nucleosome fractionation by mercury affinity chromatography. Contrasting distribution of transcriptionally active DNA sequences and acetylated histones in nucleosome fractions of wild-type yeast cells and cells expressing a histone H3 gene altered t
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mutations in the HML E silencer of Saccharomyces cerevisiae yield metastable inheritance of transcriptional repression
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Active genes in budding yeast display enhanced in vivo accessibility to foreign DNA methylases: a novel in vivo probe for chromatin structure of yeast
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The essence of inactivity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
RAP-1 factor is necessary for DNA loop formation in vitro at the silent mating type locus HML
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Changes in histone gene dosage alter transcription in yeast
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Parental legacy determines methylation and expression of an autosomal transgene: a molecular mechanism for parental imprinting
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Genomic imprinting
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Degree of methylation of transgenes is dependent on gamete of origin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identification of sites required for repression of a silent mating type locus in yeast
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Involvement of Double-strand Chromosomal Breaks for Mating-type Switching in Saccharomyces cerevisiae
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The regulation of yeast mating-type chromatin structure by SIR: An action at a distance affecting both transcription and transposition
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Role of DNA replication in the repression of silent mating type loci in yeast
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Butyrate suppression of position-effect variegation in Drosophila melanogaster
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/1480108
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MR.56.4.543-560.1992
1 reference
stated in
National Center for Biotechnology Information
PubMed publication ID
1480108
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1480108
retrieved
30 September 2022
PMC publication ID
372887
1 reference
stated in
Europe PubMed Central
PMC publication ID
372887
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1480108%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 September 2019
PubMed publication ID
1480108
1 reference
stated in
Europe PubMed Central
PMC publication ID
372887
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1480108%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 September 2019
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