(Q35209853)

7 August 2017

1 reference

title

Hyperhomocysteinemia and its role in the development of atherosclerosis (English)

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7 August 2017

1 reference

A B Lawrence de Koning

1

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7 August 2017

Geoff H Werstuck

2

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7 August 2017

Ji Zhou

3

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7 August 2017

Richard C Austin

4

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7 August 2017

publication date

1 September 2003

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7 August 2017

published in

Clinical Biochemistry

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7 August 2017

volume

36

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7 August 2017

issue

6

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7 August 2017

page(s)

431-441

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Atherosclerosis — An Inflammatory Disease

7 August 2017

cites work

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The pathogenesis of atherosclerosis: a perspective for the 1990s

7 January 2021

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Atherosclerosis: basic mechanisms. Oxidation, inflammation, and genetics

7 January 2021

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The Yin and Yang of oxidation in the development of the fatty streak. A review based on the 1994 George Lyman Duff Memorial Lecture

7 January 2021

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Reverse cholesterol transport and atherosclerosis regression

7 January 2021

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A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association.

7 January 2021

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A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association

7 January 2021

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Low density lipoprotein undergoes oxidative modification in vivo

7 January 2021

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Human Atherosclerotic Plaque Contains Both Oxidized Lipids and Relatively Large Amounts of α-Tocopherol and Ascorbate

7 January 2021

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Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man

7 January 2021

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7 January 2021

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Hyperhomocysteinemia: an independent risk factor for vascular disease

7 January 2021

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Hyperhomocysteinemia as a risk factor for deep-vein thrombosis.

7 January 2021

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Homocysteine and vascular disease

7 January 2021

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Association between Plasma Homocysteine Concentrations and Extracranial Carotid-Artery Stenosis

7 January 2021

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The controversy over homocysteine and cardiovascular risk

7 January 2021

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Homocysteine and atherothrombosis

7 January 2021

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A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

7 January 2021

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Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification

7 January 2021

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Treatment of mild hyperhomocysteinemia in vascular disease patients

7 January 2021

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The effect of a subnormal vitamin B-6 status on homocysteine metabolism

7 January 2021

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Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia

7 January 2021

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Total homocysteine lowering treatment among coronary artery disease patients in the era of folic acid-fortified cereal grain flour

7 January 2021

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Folic acid fortification, folate status and plasma homocysteine

7 January 2021

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Effect of implementation of folic acid fortification of food on homocysteine concentrations in subjects with coronary artery disease

7 January 2021

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Homocysteine and cardiovascular disease

7 January 2021

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Homocysteine and cardiovascular disease: cause or effect?

7 January 2021

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Homocyst(e)ine and cardiovascular disease: a critical review of the epidemiologic evidence

7 January 2021

1 reference

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Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis

7 January 2021

1 reference

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Homocysteine and cardiovascular risk

7 January 2021

1 reference

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Homocysteine induces expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human aortic endothelial cells: implications for vascular disease

7 January 2021

1 reference

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Homocysteine induces monocyte chemoattractant protein-1 expression by activating NF-kappaB in THP-1 macrophages

7 January 2021

1 reference

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NF-kappaB: pivotal mediator or innocent bystander in atherogenesis?

7 January 2021

1 reference

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Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model

7 January 2021

1 reference

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Endothelial dysfunction in a murine model of mild hyperhomocyst(e)inemia

7 January 2021

1 reference

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Vascular dysfunction in monkeys with diet-induced hyperhomocyst(e)inemia

7 January 2021

1 reference

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The oxidant stress of hyperhomocyst(e)inemia

7 January 2021

1 reference

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Hyperhomocyst(e)inemia is associated with impaired endothelium-dependent vasodilation in humans

7 January 2021

1 reference

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Cellular redox state and endothelial dysfunction in mildly hyperhomocysteinemic cystathionine beta-synthase-deficient mice

7 January 2021

1 reference

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Homocysteine-induced inhibition of endothelium-dependent relaxation in rabbit aorta: role for superoxide anions

7 January 2021

1 reference

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Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: an effect reversible with vitamin C therapy.

7 January 2021

1 reference

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Improved vascular endothelial function after oral B vitamins: An effect mediated through reduced concentrations of free plasma homocysteine

7 January 2021

1 reference

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Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine

7 January 2021

1 reference

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Hyperhomocysteinemia and oxidative stress: time for a reality check?

7 January 2021

1 reference

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Relative roles of albumin and ceruloplasmin in the formation of homocystine, homocysteine-cysteine-mixed disulfide, and cystine in circulation

7 January 2021

1 reference

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Is homocysteine a pro-oxidant?

7 January 2021

1 reference

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Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia

7 January 2021

1 reference

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Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

7 January 2021

1 reference

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Characterization of the stress-inducing effects of homocysteine

7 January 2021

1 reference

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Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase

7 January 2021

1 reference

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Nitric oxide regulates monocyte chemotactic protein-1

7 January 2021

1 reference

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Translational control in the endoplasmic reticulum stress response

7 January 2021

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The glucose-regulated proteins: stress induction and clinical applications

7 January 2021

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Orchestrating the unfolded protein response in health and disease

7 January 2021

1 reference

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ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

7 January 2021

1 reference

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Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum

7 January 2021

1 reference

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The protein kinase/endoribonuclease IRE1alpha that signals the unfolded protein response has a luminal N-terminal ligand-independent dimerization domain

7 January 2021

1 reference

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Translational control is required for the unfolded protein response and in vivo glucose homeostasis

7 January 2021

1 reference

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

7 January 2021

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Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress

7 January 2021

1 reference

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Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78/BiP and novel genes

7 January 2021

1 reference

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Hyperhomocysteinemia and function of the endoplasmic reticulum

7 January 2021

1 reference

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Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways

7 January 2021

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CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

7 January 2021

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Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress

7 January 2021

1 reference

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Taurine prevents the decrease in expression and secretion of extracellular superoxide dismutase induced by homocysteine: amelioration of homocysteine-induced endoplasmic reticulum stress by taurine

7 January 2021

1 reference

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Activation of JNK and transcriptional repressor ATF3/LRF1 through the IRE1/TRAF2 pathway is implicated in human vascular endothelial cell death by homocysteine

7 January 2021

1 reference

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Homocysteine induces programmed cell death in human vascular endothelial cells through activation of the unfolded protein response

7 January 2021

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Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a

7 January 2021

1 reference

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Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL

7 January 2021

1 reference

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The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane

7 January 2021

1 reference

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Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

7 January 2021

1 reference

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Regulation of the dolichol pathway in human fibroblasts by the endoplasmic reticulum unfolded protein response

7 January 2021

1 reference

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Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

7 January 2021

1 reference

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Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis

7 January 2021

1 reference

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Homocysteine thiolactone induces apoptotic DNA damage mediated by increased intracellular hydrogen peroxide and caspase 3 activation in HL-60 cells.

7 January 2021

1 reference

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Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation

7 January 2021

1 reference

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Activation of transcription factor NF-kappaB by the adenovirus E3/19K protein requires its ER retention

7 January 2021

1 reference

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A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B.

7 January 2021

1 reference

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Homocysteine induces DNA synthesis and proliferation of vascular smooth muscle cells by a hydrogen peroxide-independent mechanism

7 January 2021

1 reference

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Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis

7 January 2021

1 reference

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Induction of cyclin A gene expression by homocysteine in vascular smooth muscle cells

7 January 2021

1 reference

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Upregulation of smooth muscle cell collagen production by homocysteine-insight into the pathogenesis of homocystinuria

7 January 2021

1 reference

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Homocysteine and hypomethylation. A novel link to vascular disease

7 January 2021

1 reference

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Homocysteine, a risk factor for premature vascular disease and thrombosis, induces tissue factor activity in endothelial cells

7 January 2021

1 reference

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Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator

7 January 2021

1 reference

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Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine

7 January 2021

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Tissue plasminogen activator binding to the annexin II tail domain. Direct modulation by homocysteine

7 January 2021

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Genetic determinants of homocysteine thiolactonase activity in humans: implications for atherosclerosis.

7 January 2021

1 reference

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Effect of homocysteinylation on human high-density lipoproteins: a correlation with paraoxonase activity

7 January 2021

1 reference

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Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia

7 January 2021

1 reference

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Folate dependence of hyperhomocysteinemia and vascular dysfunction in cystathionine beta-synthase-deficient mice

7 January 2021

1 reference

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Consequences of hyperhomocyst(e)inemia on vascular function in atherosclerotic monkeys.

7 January 2021

1 reference

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Supplementation of atherogenic diet with B vitamins does not prevent atherosclerosis or vascular dysfunction in monkeys.

7 January 2021

1 reference

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Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition

7 January 2021

1 reference

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Increased monocyte adhesion to aortic endothelium in rats with hyperhomocysteinemia: role of chemokine and adhesion molecules

7 January 2021

1 reference

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Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E

7 January 2021

1 reference

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Dietary supplementation with methionine and homocysteine promotes early atherosclerosis but not plaque rupture in ApoE-deficient mice

7 January 2021

1 reference

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Homocysteine as a risk factor for vascular disease. Enhanced collagen production and accumulation by smooth muscle cells

7 January 2021

1 reference

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Homocysteine induced arteriosclerosis-like alterations of the aorta in normotensive and hypertensive rats following application of high doses of methionine

7 January 2021

1 reference

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Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice

7 January 2021

1 reference

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Expression of influenza virus hemagglutinin activates transcription factor NF-kappa B.

7 January 2021

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0009-9120(03)00062-6

1 reference

7 August 2017

1 reference