(Q35192456)

7 August 2017

title

K-ras is an essential gene in the mouse with partial functional overlap with N-ras (English)

1 reference

7 August 2017

L Johnson

1

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7 August 2017

D Greenbaum

2

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7 August 2017

K Cichowski

3

1 reference

7 August 2017

K Mercer

4

1 reference

7 August 2017

E Murphy

5

1 reference

7 August 2017

E Schmitt

6

1 reference

7 August 2017

R T Bronson

7

1 reference

7 August 2017

H Umanoff

8

1 reference

7 August 2017

W Edelmann

9

1 reference

7 August 2017

R Kucherlapati

10

1 reference

7 August 2017

T Jacks

11

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7 August 2017

publication date

1 October 1997

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7 August 2017

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7 August 2017

volume

11

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7 August 2017

issue

19

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7 August 2017

page(s)

2468-2481

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A direct measurement of the radiation sensitivity of normal mouse bone marrow cells

7 August 2017

cites work

1 reference

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Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system

28 July 2018

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Plugging it in: signaling circuits and the yeast cell cycle

28 July 2018

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Resistance of K-RasBV12 proteins to farnesyltransferase inhibitors in Rat1 cells

28 July 2018

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Hematopoiesis: how does it happen?

28 July 2018

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Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic

28 July 2018

1 reference

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The Ras signal transduction pathway

28 July 2018

1 reference

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p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

28 July 2018

1 reference

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The Ras/Raf signaling pathway is required for progression of mouse embryos through the two-cell stage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences

28 July 2018

1 reference

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The murine N-ras gene is not essential for growth and development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

The ins and outs of Raf kinases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

MAPKs: new JNK expands the group

28 July 2018

1 reference

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Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

The Ras signaling pathway in Drosophila

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Disruption of Oncogenic K-Ras4B Processing and Signaling by a Potent Geranylgeranyltransferase I Inhibitor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Mouse embryonic hematopoiesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Genes in S. cerevisiae encoding proteins with domains homologous to the mammalian ras proteins.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Genetic analysis of yeast RAS1 and RAS2 genes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Transcription of c-onc genes c-rasKi and c-fms during mouse development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Structure and expression of amplified cKi-ras gene sequences in Y1 mouse adrenal tumor cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Differential expression of the ras gene family in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Expression of p21ras in normal and malignant human tissues: lack of association with proliferation and malignancy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

The ras gene family and human carcinogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Transgenesis by means of blastocyst-derived embryonic stem cell lines

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Mutational analysis of a ras catalytic domain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Properties of the earliest clonogenic hemopoietic precursors to appear in the developing murine yolk sac.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

All ras proteins are polyisoprenylated but only some are palmitoylated

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

ras oncogenes in human cancer: a review

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

The GTPase superfamily: a conserved switch for diverse cell functions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Effect of a dominant inhibitory Ha-ras mutation on mitogenic signal transduction in NIH 3T3 cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Simplified mammalian DNA isolation procedure

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Production of homozygous mutant ES cells with a single targeting construct

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Protein prenylation: key to ras function and cancer intervention?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Anti-Ras drugs come of age.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Recent advances in understanding signal transduction pathways in worms and flies

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Comparison of kinetic properties between two mammalian ras p21 GDP/GTP exchange proteins, ras guanine nucleotide-releasing factor and smg GDP dissociation stimulation.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Small GTP-binding proteins and the regulation of the actin cytoskeleton

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316567

Role of protein modification reactions in programming interactions between ras-related GTPases and cell membranes

27 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334313

12 December 2020

Translocation of Ki-ras p21 between membrane and cytoplasm by smg GDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334313

12 December 2020

Expression of ras proto-oncogene proteins in normal human tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334313

12 December 2020

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334313

12 December 2020

Differential expression of cellular oncogenes during pre- and postnatal development of the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334313

12 December 2020

Different functions of Smg GDP dissociation stimulator and mammalian counterpart of yeast Cdc25

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334313

12 December 2020

Identifiers

DOI

10.1101/GAD.11.19.2468

1 reference

7 August 2017

1 reference

7 August 2017

1 reference