(Q35170422)

English

Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2. (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Jesper Nylandsted

1

object named as

J Nylandsted

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Marja Jäättelä

1 reference

ORCID Public Data File 2021

author name string

M Rohde

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

K Brand

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

L Bastholm

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

F Elling

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

M Jäättelä

6

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

0 references

publication date

1 July 2000

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

97

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

14

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

7871-7876

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Calpain and caspase: can you tell the difference?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Apoptosis without caspases: an inefficient molecular guillotine?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Oncogenic potential of Hsp72.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Escaping cell death: survival proteins in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

In vivo chaperone activity of heat shock protein 70 and thermotolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Molecular characterization of mitochondrial apoptosis-inducing factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Heat shock protein 70 kDa: molecular biology, biochemistry, and physiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Tobacco smoke induces both apoptosis and necrosis in mammalian cells: differential effects of HSP70.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Caspases: enemies within

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Apoptosis, cancer and cancer therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Heat shock proteins and cell proliferation in human breast cancer biopsy samples

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

A hitchhiker's guide to the human Hsp70 family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Involvement of caspase-dependent activation of cytosolic phospholipase A2 in tumor necrosis factor-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Differential suppression by protease inhibitors and cytokines of apoptosis induced by wild-type p53 and cytotoxic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Heat shock protein hsp70 in patients with axillary lymph node-negative breast cancer: prognostic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Heat-shock proteins protect cells from monocyte cytotoxicity: possible mechanism of self-protection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Purification of a 24-kD protease from apoptotic tumor cells that activates DNA fragmentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Bcl-x and Bcl-2 inhibit TNF and Fas-induced apoptosis and activation of phospholipase A2 in breast carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Expression of human HSP70 during the synthetic phase of the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

70-kD heat shock-related protein is one of at least two distinct cytosolic factors stimulating protein import into mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Widespread long-term gene transfer to mouse skeletal muscles and heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

The transport of proteins into the nucleus requires the 70-kilodalton heat shock protein or its cytosolic cognate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Major heat shock protein hsp70 protects tumor cells from tumor necrosis factor cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Diversity of human p53 mutants revealed by complex formation to SV40 T antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

13 July 2018

Oncogenic Ras triggers cell suicide through the activation of a caspase-independent cell death program in human cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

27 September 2018

Mechanisms of apoptosis avoidance in cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

27 September 2018

Liver-associated toxicity of the HSV-tk/GCV approach and adenoviral vectors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16637

27 September 2018

A matter of life and cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/10884417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 prevents caspase-independent cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/10884417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis induced by vitamin D compounds in breast cancer cells is inhibited by Bcl-2 but does not involve known caspases or p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/10884417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptosis by abrogation of HSP70 expression in human oral cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10884417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection from tumor necrosis factor cytotoxicity by protease inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10884417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Over-expression of hsp70 confers tumorigenicity to mouse fibrosarcoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10884417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of proliferation and induction of apoptosis by abrogation of heat-shock protein (HSP) 70 expression in tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10884417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell lymphoma in transgenic mice expressing the human Hsp70 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/10884417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proliferating cell nuclear antigen and heat shock protein 70 immunolocalization in invasive ductal breast cancer not otherwise specified

1 reference

https://pubmed.ncbi.nlm.nih.gov/10884417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated cell cycle checkpoints in epirubicin-treated breast cancer cells studied by BrdUrd-flow cytometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/10884417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat shock protein expression and drug resistance in breast cancer patients treated with induction chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/10884417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.97.14.7871

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

2000PNAS...97.7871N

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

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