(Q35120707)

6 August 2017

title

Mechanisms of cytochrome c release by proapoptotic BCL-2 family members (English)

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6 August 2017

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https://api.crossref.org/works/10.1016/S0006-291X(03)00615-6

30 December 2023

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https://api.crossref.org/works/10.1016/S0006-291X(03)00615-6

30 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0006-291X(03)00615-6

30 December 2023

2

Stanley J Korsmeyer

1 reference

6 August 2017

1

Luca Scorrano

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12729577

30 December 2023

language of work or name

English

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publication date

1 May 2003

1 reference

6 August 2017

9 May 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12729577

full work available at URL

30 December 2023

https://api.elsevier.com/content/article/PII:S0006291X03006156?httpAccept=text/xml

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https://api.crossref.org/works/10.1016/S0006-291X(03)00615-6

https://api.elsevier.com/content/article/PII:S0006291X03006156?httpAccept=text/plain

30 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0006-291X(03)00615-6

Biochemical and Biophysical Research Communications

30 December 2023

published in

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6 August 2017

volume

304

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6 August 2017

issue

3

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6 August 2017

page(s)

437-444

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

6 August 2017

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Mitochondria and apoptosis

7 January 2021

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BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

7 January 2021

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Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis

7 January 2021

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Apaf1 is required for mitochondrial pathways of apoptosis and brain development

7 January 2021

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Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

7 January 2021

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Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

7 January 2021

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Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

7 January 2021

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BCL-2 family members and the mitochondria in apoptosis

7 January 2021

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

7 January 2021

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

7 January 2021

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Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis

7 January 2021

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The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol

7 January 2021

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Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

7 January 2021

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Bim: a novel member of the Bcl-2 family that promotes apoptosis

7 January 2021

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Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

7 January 2021

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The BH3 domain of Bcl-x(S) is required for inhibition of the antiapoptotic function of Bcl-x(L).

7 January 2021

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Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL.

7 January 2021

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Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange

7 January 2021

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

7 January 2021

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

7 January 2021

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Bid acts on the permeability transition pore complex to induce apoptosis

7 January 2021

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Activation of mitochondrial voltage-dependent anion channel by apro-apoptotic BH3-only protein Bim

7 January 2021

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Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

7 January 2021

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

7 January 2021

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BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity

7 January 2021

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Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

7 January 2021

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Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis

7 January 2021

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Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

7 January 2021

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Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells

7 January 2021

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BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

7 January 2021

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Structure of Bax: coregulation of dimer formation and intracellular localization

7 January 2021

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Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

7 January 2021

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

7 January 2021

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The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

7 January 2021

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Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

7 January 2021

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A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis

7 January 2021

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Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

7 January 2021

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Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

7 January 2021

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Mitochondrial transport of cations: channels, exchangers, and permeability transition.

7 January 2021

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Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

7 January 2021

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The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition

7 January 2021

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Bax directly induces release of cytochrome c from isolated mitochondria

7 January 2021

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Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions

7 January 2021

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Imaging the permeability pore transition in single mitochondria

7 January 2021

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Mitochondria Are Excitable Organelles Capable of Generating and Conveying Electrical and Calcium Signals

7 January 2021

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Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence

7 January 2021

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The inner mitochondrial membrane contains ion-conducting channels similar to those found in bacteria.

7 January 2021

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Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore

7 January 2021

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Cytochrome c release occurs via Ca2+-dependent and Ca2+-independent mechanisms that are regulated by Bax.

7 January 2021

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BAX-dependent transport of cytochrome c reconstituted in pure liposomes

7 January 2021

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A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast

7 January 2021

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The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

7 January 2021

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Cytochrome c release from mitochondria: all or nothing

7 January 2021

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A reversible component of mitochondrial respiratory dysfunction in apoptosis can be rescued by exogenous cytochrome c.

7 January 2021

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Injected cytochrome c induces apoptosis

7 January 2021

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Endogenous inhibitors of caspases

7 January 2021

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IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

7 January 2021

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X-linked IAP is a direct inhibitor of cell-death proteases

7 January 2021

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The internal structure of mitochondria

7 January 2021

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Quantitative cytochemistry of the diaminobenzidine cytochrome oxidase reaction product in mitochondria of cardiac muscle and pancreas

7 January 2021

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Ultrastructural localization of cytochrome c in apoptosis demonstrates mitochondrial heterogeneity.

7 January 2021

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Topology of the mitochondrial inner membrane: dynamics and bioenergetic implications.

7 January 2021

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Proapoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity

7 January 2021

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Mitochondrial ultracondensation, but not swelling, is involved in TNF alpha-induced apoptosis in human T-lymphoblastic leukaemic cells.

7 January 2021

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Mitochondrial proliferation and paradoxical membrane depolarization during terminal differentiation and apoptosis in a human colon carcinoma cell line

7 January 2021

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Tumor Necrosis Factor-α Increases the Steady-state Reduction of Cytochromebof the Mitochondrial Respiratory Chain in Metabolically Inhibited L929 Cells

7 January 2021

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Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis.

7 January 2021

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Cytochrome c release from mitochondria proceeds by a two-step process

7 January 2021

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Rate-limiting step preceding cytochrome c release in cells primed for Fas-mediated apoptosis revealed by analysis of cellular mosaicism of respiratory changes

7 January 2021

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A thermodynamic model describing the nature of the crista junction: a structural motif in the mitochondrion.

7 January 2021

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Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, and cyclosporin A-sensitive channel.

7 January 2021

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Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

7 January 2021

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The apoptotic protein tBid promotes leakage by altering membrane curvature

7 January 2021

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Intrinsic curvature hypothesis for biomembrane lipid composition: a role for nonbilayer lipids

7 January 2021

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Bid, a widely expressed proapoptotic protein of the Bcl-2 family, displays lipid transfer activity.

7 January 2021

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The machinery of mitochondrial inheritance and behavior

7 January 2021

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Organelle division: Self-assembling GTPase caught in the middle

7 January 2021

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7 January 2021

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The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

7 January 2021

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7 January 2021

3

15

2922

Wang

2001

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30 December 2023

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14

2060

Wei

2000

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30 December 2023

Identifiers

1 reference

6 August 2017

1 reference