(Q35014313)

5 August 2017

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title

Molecular recognition in antibody-antigen complexes (English)

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5 August 2017

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Eric J Sundberg

1

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5 August 2017

Roy A Mariuzza

series ordinal

2

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5 August 2017

publication date

1 January 2002

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Advances in Protein Chemistry

5 August 2017

published in

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5 August 2017

volume

61

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5 August 2017

page(s)

119-160

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Effects of site-specific amino acid modification on protein interactions and biological function

5 August 2017

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Probing the importance of second sphere residues in an esterolytic antibody by phage display

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7 January 2021

Affinity dependence of the B cell response to antigen: a threshold, a ceiling, and the importance of off-rate

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7 January 2021

Three-dimensional structure of an idiotope–anti-idiotope complex

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7 January 2021

Head-to-tail dimers and interdomain flexibility revealed by the crystal structure of HIV-1 capsid protein (p24) complexed with a monoclonal antibody Fab.

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7 January 2021

Structure of influenza virus haemagglutinin complexed with a neutralizing antibody.

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7 January 2021

Anatomy of hot spots in protein interfaces

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7 January 2021

The crystal structure of the antibody N10-staphylococcal nuclease complex at 2.9 A resolution

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7 January 2021

Anatomy of an antibody molecule: structure, kinetics, thermodynamics and mutational studies of the antilysozyme antibody D1.3.

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7 January 2021

Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1

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7 January 2021

Conservation of water molecules in an antibody-antigen interaction

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7 January 2021

Crystal structure of an Fv-Fv idiotope-anti-idiotope complex at 1.9 A resolution

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7 January 2021

Crystal Structure of the Complex of the Variable Domain of Antibody D1.3 and Turkey Egg White Lysozyme: A Novel Conformational Change in Antibody CDR-L3 Selects for Antigen

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7 January 2021

Computational methodology for estimating changes in free energies of biomolecular association upon mutation. The importance of bound water in dimer-tetramer assembly for beta 37 mutant hemoglobins.

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7 January 2021

Structure of an antibody-lysozyme complex unexpected effect of conservative mutation

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7 January 2021

The nature of the accessible and buried surfaces in proteins

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7 January 2021

Principles of protein-protein recognition

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7 January 2021

Conformations of immunoglobulin hypervariable regions

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7 January 2021

Structural repertoire of the human VH segments

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7 January 2021

A hot spot of binding energy in a hormone-receptor interface

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7 January 2021

Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity

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7 January 2021

Three-dimensional structure of a complex of antibody with influenza virus neuraminidase

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7 January 2021

Analysis of protein-protein interactions and the effects of amino acid mutations on their energetics. The importance of water molecules in the binding epitope

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7 January 2021

A mutational analysis of the binding of two different proteins to the same antibody

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7 January 2021

A mutational analysis of binding interactions in an antigen-antibody protein-protein complex

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7 January 2021

A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops

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7 January 2021

Solvation energy in protein folding and binding

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7 January 2021

Response of a protein structure to cavity-creating mutations and its relation to the hydrophobic effect

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7 January 2021

Exploring the mimicry of polysaccharide antigens by anti-idiotypic antibodies. The crystallization, molecular replacement, and refinement to 2.8 A resolution of an idiotope-anti-idiotope Fab complex and of the unliganded anti-idiotope Fab.

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7 January 2021

Relationships between apparent binding energies measured in site-directed mutagenesis experiments and energetics of binding and catalysis

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7 January 2021

Hydrogen bonding and biological specificity analysed by protein engineering

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7 January 2021

Molecular basis of antigen mimicry by an anti-idiotope

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7 January 2021

Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme

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7 January 2021

Three-dimensional structure of an angiotensin II-Fab complex at 3 A: hormone recognition by an anti-idiotypic antibody

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7 January 2021

Recognition of angiotensin II: antibodies at different levels of an idiotypic network are superimposable

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7 January 2021

The effect of water activity on the association constant and the enthalpy of reaction between lysozyme and the specific antibodies D1.3 and D44.1.

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7 January 2021

Analysis of binding interactions in an idiotope-antiidiotope protein-protein complex by double mutant cycles

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7 January 2021

Patterns of nonadditivity between pairs of stability mutations in staphylococcal nuclease

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7 January 2021

Naturally occurring antibodies devoid of light chains

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7 January 2021

X-ray structure of a monoclinic form of hen egg-white lysozyme crystallized at 313 K. Comparison of two independent molecules

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7 January 2021

An autoantibody to single-stranded DNA: Comparison of the three-dimensional structures of the unliganded fab and a deoxynucleotide-fab complex

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7 January 2021

High resolution structures of the 4–4-20 Fab-fluorescein complex in two solvent systems: effects of solvent on structure and antigen-binding affinity

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7 January 2021

The three-dimensional structure of a T-cell antigen receptor V alpha V beta heterodimer reveals a novel arrangement of the V beta domain

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7 January 2021

The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex

1 reference

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7 January 2021

Wet and dry interfaces: the role of solvent in protein-protein and protein-DNA recognition

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7 January 2021

Antigen binding thermodynamics and antiproliferative effects of chimeric and humanized anti-p185HER2 antibody Fab fragments

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7 January 2021

Energetics of complementary side-chain packing in a protein hydrophobic core

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7 January 2021

Crystal structure of anti-Hen egg white lysozyme antibody (HyHEL-10) Fv-antigen complex. Local structural changes in the protein antigen and water-mediated interactions of Fv-antigen and light chain-heavy chain interfaces

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7 January 2021

The influence of temperature on lysozyme crystals. Structure and dynamics of protein and water

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7 January 2021

Shape complementarity at protein/protein interfaces

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7 January 2021

Analysis of antigenic surfaces of proteins

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7 January 2021

Aromatic rings act as hydrogen bond acceptors

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7 January 2021

Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,)

1 reference

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7 January 2021

Long-range, small magnitude nonadditivity of mutational effects in proteins

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7 January 2021

The atomic structure of protein-protein recognition sites

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7 January 2021

Antibody-antigen interactions: contact analysis and binding site topography.

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7 January 2021

The structure of a complex between the NC10 antibody and influenza virus neuraminidase and comparison with the overlapping binding site of the NC41 antibody

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7 January 2021

Maturation of an antibody response is governed by modulations in flexibility of the antigen-combining site

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7 January 2021

Hydrophobic stabilization in T4 lysozyme determined directly by multiple substitutions of Ile 3

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7 January 2021

Mutual conformational adaptations in antigen and antibody upon complex formation between an Fab and HIV-1 capsid protein p24

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7 January 2021

VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface

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7 January 2021

Structural basis for the binding of an anti-cytochrome c antibody to its antigen: crystal structures of FabE8-cytochrome c complex to 1.8 A resolution and FabE8 to 2.26 A resolution

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7 January 2021

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

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7 January 2021

On the nature of antibody combining sites: Unusual structural features that may confer on these sites an enhanced capacity for binding ligands

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7 January 2021

Anti-idiotypic antibodies: biological function and structural studies.

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7 January 2021

The immunological evolution of catalysis

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7 January 2021

Clonal selection and learning in the antibody system

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7 January 2021

Refinement of triclinic lysozyme: II. The method of stereochemically restrained least squares

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7 January 2021

Structural evidence for induced fit as a mechanism for antibody-antigen recognition

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7 January 2021

Immunological origins of binding and catalysis in a Diels-Alderase antibody

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7 January 2021

Estimating the contribution of engineered surface electrostatic interactions to protein stability by using double-mutant cycles

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7 January 2021

Reconciling the magnitude of the microscopic and macroscopic hydrophobic effects

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7 January 2021

Predicting the structure of protein complexes: a step in the right direction

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7 January 2021

Contributions of the large hydrophobic amino acids to the stability of staphylococcal nuclease

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7 January 2021

Sensitive titration microcalorimetric study of the binding of Salmonella O-antigenic oligosaccharides by a monoclonal antibody

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7 January 2021

Crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 A

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7 January 2021

Major antigen-induced domain rearrangements in an antibody

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7 January 2021

Luxury accommodations: the expanding role of structural plasticity in protein-protein interactions

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7 January 2021

Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface

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7 January 2021

Contribution of hydrophobic residues to the stability of human lysozyme: calorimetric studies and X-ray structural analysis of the five isoleucine to valine mutants

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7 January 2021

Contribution of the hydrophobic effect to the stability of human lysozyme: calorimetric studies and X-ray structural analyses of the nine valine to alanine mutants

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7 January 2021

The structural repertoire of the human V kappa domain

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7 January 2021

The Imprint of Somatic Hypermutation on the Repertoire of Human Germline V Genes

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7 January 2021

Somatic generation of antibody diversity

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7 January 2021

Refined crystal structure of the influenza virus N9 neuraminidase-NC41 Fab complex

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7 January 2021

The interplay between binding energy and catalysis in the evolution of a catalytic antibody

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7 January 2021

Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody

1 reference

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7 January 2021

Structural insights into the evolution of an antibody combining site

1 reference

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7 January 2021

Crystal structures of the free and liganded form of an esterolytic catalytic antibody

1 reference

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7 January 2021

Hematopoietic receptor complexes

1 reference

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7 January 2021

TCR binding to peptide-MHC stabilizes a flexible recognition interface

1 reference

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7 January 2021

Antibody-antigen interactions: new structures and new conformational changes

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7 January 2021

The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect.

1 reference

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7 January 2021

Mutational analysis of the affinity maturation of antibody 48G7.

1 reference

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7 January 2021

Solvent Rearrangement in an Antigen—Antibody Interface Introduced by Site-directed Mutagenesis of the Antibody Combining Site

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7 January 2021

10.1016/S0065-3233(02)61004-6

Identifiers

DOI

1 reference

5 August 2017

1 reference