(Q34641903)

3 August 2017

title

Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma (English)

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3 August 2017

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12

Sabine Mueller

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3 August 2017

Rintaro Hashizume

1

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3 August 2017

Noemi Andor

2

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3 August 2017

Yuichiro Ihara

3

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3 August 2017

Robin Lerner

4

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3 August 2017

Haiyun Gan

5

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3 August 2017

Xiaoyue Chen

6

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3 August 2017

Dong Fang

7

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3 August 2017

Xi Huang

8

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3 August 2017

Maxwell W Tom

9

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3 August 2017

Vy Ngo

10

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3 August 2017

David Solomon

11

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3 August 2017

Pamela L Paris

13

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3 August 2017

Zhiguo Zhang

14

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3 August 2017

Claudia Petritsch

15

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3 August 2017

Nalin Gupta

16

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3 August 2017

Todd A Waldman

17

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3 August 2017

C David James

18

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3 August 2017

language of work or name

English

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publication date

17 November 2014

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3 August 2017

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3 August 2017

volume

20

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3 August 2017

issue

12

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3 August 2017

page(s)

1394-1396

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Targeting Wee1 for the treatment of pediatric high-grade gliomas

3 August 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

Brainstem glioma: a review

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

Fast gapped-read alignment with Bowtie 2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

An experimental xenograft mouse model of diffuse pontine glioma designed for therapeutic testing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

Design and analysis of ChIP-seq experiments for DNA-binding proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

Polycomb complexes and silencing mechanisms.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257862

26 October 2018

Identifiers

DOI

10.1038/NM.3716

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3 August 2017

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3 August 2017

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