(Q34626763)

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22 January 2020

title

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis (English)

1 reference

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22 January 2020

0 references

4

1 reference

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22 January 2020

Jurre J Kamphorst

7

1 reference

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22 January 2020

Eileen White

15

1 reference

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22 January 2020

14

Joshua D Rabinowitz

1 reference

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22 January 2020

author name string

Jessie Yanxiang Guo

1

1 reference

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22 January 2020

Hsin-Yi Chen

2

1 reference

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22 January 2020

Robin Mathew

3

1 reference

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22 January 2020

Anne M Strohecker

5

1 reference

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22 January 2020

Gizem Karsli-Uzunbas

6

1 reference

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22 January 2020

Guanghua Chen

8

1 reference

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22 January 2020

Johanna M S Lemons

9

1 reference

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22 January 2020

Vassiliki Karantza

10

1 reference

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22 January 2020

Hilary A Coller

11

1 reference

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22 January 2020

Robert S Dipaola

12

1 reference

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22 January 2020

Celine Gelinas

13

1 reference

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22 January 2020

publication date

11 February 2011

1 reference

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22 January 2020

1 reference

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22 January 2020

volume

25

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22 January 2020

issue

5

1 reference

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22 January 2020

page(s)

460-470

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21317241%20AND%20SRC:MED&resulttype=core&format=json

Pancreatic cancers require autophagy for tumor growth

22 January 2020

cites work

1 reference

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7 July 2018

Autophagy and metabolism

1 reference

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Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

7 July 2018

1 reference

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Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy

7 July 2018

1 reference

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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Mitochondrial reserve capacity in endothelial cells: The impact of nitric oxide and reactive oxygen species

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Role of autophagy in suppression of inflammation and cancer

7 July 2018

1 reference

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The double-edged sword of autophagy modulation in cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Autophagy suppresses tumorigenesis through elimination of p62

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: spare respiratory capacity and stochastic mitochondrial failure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Understanding the Warburg effect: the metabolic requirements of cell proliferation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

7 July 2018

1 reference

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The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis

7 July 2018

1 reference

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Autophagy in the Pathogenesis of Disease

7 July 2018

1 reference

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Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Role of autophagy in cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Autophagy suppresses tumor progression by limiting chromosomal instability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Dynamics of the cellular metabolome during human cytomegalovirus infection

7 July 2018

1 reference

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Cancer's molecular sweet tooth and the Warburg effect.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Genome-scale loss-of-function screening with a lentiviral RNAi library

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Loss of autophagy in the central nervous system causes neurodegeneration in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Mitochondrial tumour suppressors: a genetic and biochemical update

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

The role of autophagy during the early neonatal starvation period

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Hypoxia and defective apoptosis drive genomic instability and tumorigenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

On respiratory impairment in cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

BAX and BAK mediate p53-independent suppression of tumorigenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Bax and Bak independently promote cytochrome C release from mitochondria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

Mitochondria get a Parkin' ticket

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049287

9 December 2018

Identifiers

DOI

10.1101/GAD.2016311

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21317241%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21317241%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

21317241

1 reference