(Q34483551)

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Splicing speckles are not reservoirs of RNA polymerase II, but contain an inactive form, phosphorylated on serine2 residues of the C-terminal domain

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Europe PubMed Central

PubMed publication ID

2 August 2017

Splicing speckles are not reservoirs of RNA polymerase II, but contain an inactive form, phosphorylated on serine2 residues of the C-terminal domain (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

phosphorylation

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David L Bentley

object named as

David L Bentley

4

0 references

object named as

Ana Pombo

5

0 references

Pascale V Guillot

object named as

Pascale V Guillot

3

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author name string

Sheila Q Xie

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Sonya Martin

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

publication date

8 February 2006

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Molecular Biology of the Cell

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

17

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

1723-1733

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

P54nrb forms a heterodimer with PSP1 that localizes to paraspeckles in an RNA-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Cajal bodies, nucleoli, and speckles in the Xenopus oocyte nucleus have a low-density, sponge-like structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

RNA polymerase II carboxy-terminal domain phosphorylation is required for cotranscriptional pre-mRNA splicing and 3'-end formation

1 reference

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6 July 2018

Expression and functional significance of mouse paraspeckle protein 1 on spermatogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

The link between mRNA processing and transcription: communication works both ways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Poly(A)+ RNAs roam the cell nucleus and pass through speckle domains in transcriptionally active and inactive cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

p54(nrb) associates with the 5' splice site within large transcription/splicing complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Repositioning of Muscle-specific Genes Relative to the Periphery of SC-35 Domains during Skeletal Myogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Clustering of multiple specific genes and gene-rich R-bands around SC-35 domains: evidence for local euchromatic neighborhoods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Nuclear speckles: a model for nuclear organelles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Evidence that all SC-35 domains contain mRNAs and that transcripts can be structurally constrained within these domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

The transcription cycle of RNA polymerase II in living cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Splicing and transcription-associated proteins PSF and p54nrb/nonO bind to the RNA polymerase II CTD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Regulation of transcription elongation by phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

An extensive network of coupling among gene expression machines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

The Cdk9 and cyclin T subunits of TAK/P-TEFb localize to splicing factor-rich nuclear speckle regions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Participation of the C-terminal domain of RNA polymerase II in exon definition during pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Dynamic association of capping enzymes with transcribing RNA polymerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Tracking COL1A1 RNA in osteogenesis imperfecta. splice-defective transcripts initiate transport from the gene but are retained within the SC35 domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Reduced mobility of the alternate splicing factor (ASF) through the nucleoplasm and steady state speckle compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Compartmentalization of RNA processing factors within nuclear speckles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

High mobility of proteins in the mammalian cell nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Isolation and characterization of monoclonal antibodies directed against subunits of human RNA polymerases I, II, and III

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Three-dimensional visualization of transcription sites and their association with splicing factor-rich nuclear speckles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Purification and biochemical characterization of interchromatin granule clusters

1 reference

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6 July 2018

Phosphorylated RNA polymerase II stimulates pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Ultrastructural analysis of transcription and splicing in the cell nucleus after bromo-UTP microinjection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

The path of transcripts from extra-nucleolar synthetic sites to nuclear pores: transcripts in transit are concentrated in discrete structures containing SR proteins

1 reference

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6 July 2018

Numbers and organization of RNA polymerases, nascent transcripts, and transcription units in HeLa nuclei.

1 reference

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6 July 2018

Coiled bodies and U2 snRNA genes adjacent to coiled bodies are enriched in factors required for snRNA transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Dynamic relocation of transcription and splicing factors dependent upon transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Quantitative digital analysis of diffuse and concentrated nuclear distributions of nascent transcripts, SC35 and poly(A).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Ultrastructure of the nucleus in relation to transcription and splicing: roles of perichromatin fibrils and interchromatin granules

1 reference

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6 July 2018

Multifunctional compartments in the nucleus: insights from DNA and RNA localization

1 reference

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6 July 2018

In vivo degradation of RNA polymerase II largest subunit triggered by alpha-amanitin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

A hyperphosphorylated form of the large subunit of RNA polymerase II is associated with splicing complexes and the nuclear matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

A serine kinase regulates intracellular localization of splicing factors in the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Cytostellin distributes to nuclear regions enriched with splicing factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Dynamics of transcription and pre-mRNA splicing within the mammalian cell nucleus

1 reference

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6 July 2018

Colocalization of a high molecular mass phosphoprotein of the nuclear matrix (p255) with spliceosomes

1 reference

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6 July 2018

Transcription-dependent redistribution of the large subunit of RNA polymerase II to discrete nuclear domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Transcription-dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Cytostellin: a novel, highly conserved protein that undergoes continuous redistribution during the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

6 July 2018

Distribution of different phosphorylated forms of RNA polymerase II in relation to Cajal and PML bodies in human cells: an ultrastructural study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

27 October 2018

Fixation-induced redistribution of hyperphosphorylated RNA polymerase II in the nucleus of human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

27 October 2018

The distribution of RNA polymerase II largest subunit (RPB1) in the Xenopus germinal vesicle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

27 October 2018

Functional interaction of yeast pre-mRNA 3' end processing factors with RNA polymerase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

27 October 2018

Proteomics: the nucleolus weighs in.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

27 October 2018

Regional specialization in human nuclei: visualization of discrete sites of transcription by RNA polymerase III.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

27 October 2018

Active RNA polymerases are localized within discrete transcription "factories' in human nuclei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1415300

9 December 2018

Heat shock-induced alterations in phosphorylation of the largest subunit of RNA polymerase II as revealed by monoclonal antibodies CC-3 and MPM-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/16467386

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian cell lines expressing functional RNA polymerase II tagged with the green fluorescent protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16467386

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of pre-mRNA splicing factors at sites of RNA polymerase II transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/16467386

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear distribution of transcription factors in relation to sites of transcription and RNA polymerase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/16467386

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth-related changes in phosphorylation of yeast RNA polymerase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/16467386

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bridging the Resolution Gap: Imaging the Same Transcription Factories in Cryosections by Light and Electron Microscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16467386

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16467386

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paraspeckles: a novel nuclear domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16467386

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.E05-08-0726

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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