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'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance.
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Europe PubMed Central
PubMed publication ID
9630590
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9630590%20AND%20SRC:MED&resulttype=core&format=json
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12 November 2019
review article
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Europe PubMed Central
title
'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9630590
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9630590%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
main subject
fatty acid
0 references
endocannabinoids
0 references
author
Vincenzo Di Marzo
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9630590
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9630590%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
author name string
V Di Marzo
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
9630590
retrieved
2 August 2017
language of work or name
English
0 references
publication date
1 June 1998
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9630590
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9630590%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
number of pages
23
1 reference
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inferred from page(s)
published in
Biochimica et Biophysica Acta
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9630590
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9630590%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
volume
1392
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9630590
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9630590%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
issue
2-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9630590
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9630590%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
page(s)
153-175
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9630590
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9630590%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
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Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor
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Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides
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Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide
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The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons
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Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor
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Chemical characterization of a family of brain lipids that induce sleep
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Cerebrodiene, arachidonyl-ethanolamide, and hybrid structures: potential for interaction with brain cannabinoid receptors
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Anandamide may mediate sleep induction
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cis-9,10-octadecenoamide, an endogenous sleep-inducing CNS compound, inhibits lymphocyte proliferation
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Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
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2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain
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Structure of a cannabinoid receptor and functional expression of the cloned cDNA
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An amino-terminal variant of the central cannabinoid receptor resulting from alternative splicing
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Anandamide, a brain endogenous compound, interacts specifically with cannabinoid receptors and inhibits adenylate cyclase
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Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction
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Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors augments cAMP accumulation in striatal neurons: evidence for a Gs linkage to the CB1 receptor.
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Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor.
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Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neurons
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Is the cannabinoid CB1 receptor a 2-arachidonoylglycerol receptor? Structural requirements for triggering a Ca2+ transient in NG108-15 cells
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Inhibition by 2-arachidonoylglycerol, a novel type of possible neuromodulator, of the depolarization-induced increase in intracellular free calcium in neuroblastoma x glioma hybrid NG108-15 cells.
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Signaling pathway associated with stimulation of CB2 peripheral cannabinoid receptor. Involvement of both mitogen-activated protein kinase and induction of Krox-24 expression
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The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide
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SR141716A, a potent and selective antagonist of the brain cannabinoid receptor
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Regulation of a neuronal form of focal adhesion kinase by anandamide
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Cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes
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Identification and characterization of the leech CNS cannabinoid receptor: coupling to nitric oxide release
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Morphine- and anandamide-stimulated nitric oxide production inhibits presynaptic dopamine release
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Tetrahydrocannabinol inhibition of macrophage nitric oxide production
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7 January 2021
Anandamide- and delta9-tetrahydrocannabinol-evoked arachidonic acid mobilization and blockade by SR141716A [N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4 -methyl-1H-pyrazole-3-carboximide hydrochloride].
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7 January 2021
The endogenous cannabimimetic eicosanoid, anandamide, induces arachidonate release in J774 mouse macrophages.
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Receptor mediation in cannabinoid stimulated arachidonic acid mobilization and anandamide synthesis
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7 January 2021
Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes
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7 January 2021
(R)-methanandamide inhibits receptor-induced calcium responses by depleting internal calcium stores in cultured astrocytes
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7 January 2021
Isolation, identification and synthesis of an endogenous arachidonic amide that inhibits calcium channel antagonist 1,4-dihydropyridine binding
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7 January 2021
Effects of anandamide and arachidonic acid on specific binding of (+) -PN200-110, diltiazem and (-) -desmethoxyverapamil to L-type Ca2+ channel
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7 January 2021
Anandamide, an endogenous cannabinoid, inhibits Shaker-related voltage-gated K+ channels.
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7 January 2021
Cannabinoid agonists inhibit the activation of 5-HT3 receptors in rat nodose ganglion neurons
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7 January 2021
High-performance liquid chromatography and fluorometric detection of arachidonylethanolamide (anandamide) and its analogues, derivatized with 4-(N-chloroformylmethyl-N-methyl)amino-7-N,N-dimethylaminosulp honyl-2,1 ,3- benzoxadiazole (DBD-COCl).
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7 January 2021
Enzymatic synthesis of anandamide, an endogenous cannabinoid receptor ligand, through N-acylphosphatidylethanolamine pathway in testis: involvement of Ca(2+)-dependent transacylase and phosphodiesterase activities
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7 January 2021
Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines
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7 January 2021
Occurrence and postmortem generation of anandamide and other long-chain N-acylethanolamines in mammalian brain
1 reference
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7 January 2021
Isotope dilution mass spectrometric measurements indicate that arachidonylethanolamide, the proposed endogenous ligand of the cannabinoid receptor, accumulates in rat brain tissue post mortem but is contained at low levels in or is absent from fresh
1 reference
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7 January 2021
Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat.
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7 January 2021
Production and physiological actions of anandamide in the vasculature of the rat kidney.
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7 January 2021
Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation
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7 January 2021
Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes
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7 January 2021
Anandamide and other N-acylethanolamines in mouse peritoneal macrophages
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7 January 2021
A second endogenous cannabinoid that modulates long-term potentiation
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7 January 2021
The sleep inducing factor oleamide is produced by mouse neuroblastoma cells
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7 January 2021
Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes
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7 January 2021
Partial purification and characterization of the porcine brain enzyme hydrolyzing and synthesizing anandamide
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7 January 2021
Reversible hydrolysis and synthesis of anandamide demonstrated by recombinant rat fatty-acid amide hydrolase
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7 January 2021
The cloned rat hydrolytic enzyme responsible for the breakdown of anandamide also catalyzes its formation via the condensation of arachidonic acid and ethanolamine
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7 January 2021
Formation and inactivation of endogenous cannabinoid anandamide in central neurons
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7 January 2021
Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonoylethanolamine, an endogenous cannabinoid-receptor ligand, in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine
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7 January 2021
Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells
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7 January 2021
Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain.
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7 January 2021
Biosynthesis of an endogenous cannabinoid precursor in neurons and its control by calcium and cAMP.
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7 January 2021
Occurrence and metabolism of anandamide and related acyl-ethanolamides in ovaries of the sea urchin Paracentrotus lividus.
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7 January 2021
Metabolism of unique diarachidonoyl and linoleoylarachidonoyl species of ethanolamine and choline phosphoglycerides in rat testes
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7 January 2021
Alterations of fatty acyl turnover in macrophage glycerolipids induced by stimulation. Evidence for enhanced recycling of arachidonic acid
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7 January 2021
The uterus is a potential site for anandamide synthesis and hydrolysis: differential profiles of anandamide synthase and hydrolase activities in the mouse uterus during the periimplantation period
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7 January 2021
Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells
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7 January 2021
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Fatty acid amide biosynthesis: a possible new role for peptidylglycine alpha-amidating enzyme and acyl-coenzyme A: glycine N-acyltransferase
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Functional role of high-affinity anandamide transport, as revealed by selective inhibition
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7 January 2021
The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: connections with anandamide
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7 January 2021
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7 January 2021
Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization
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Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain
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Inhibition of anandamide amidase activity in mouse brain microsomes by cannabinoids
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7 January 2021
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
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7 January 2021
Two novel classes of neuroactive fatty acid amides are substrates for mouse neuroblastoma ‘anandamide amidohydrolase’
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Molecular characterization of human and mouse fatty acid amide hydrolases
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7 January 2021
Distribution of anandamide amidohydrolase in rat tissues with special reference to small intestine
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7 January 2021
Metabolism of anandamide, an endogenous cannabinoid receptor ligand, in porcine ocular tissues
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7 January 2021
Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand
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Novel Inhibitors of Brain, Neuronal, and Basophilic Anandamide Amidohydrolase
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7 January 2021
Methyl arachidonyl fluorophosphonate: a potent irreversible inhibitor of anandamide amidase
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7 January 2021
Fatty acid sulfonyl fluorides inhibit anandamide metabolism and bind to the cannabinoid receptor
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7 January 2021
Inhibition of anandamide hydrolysis in rat brain tissue by (E)-6-(bromomethylene) tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one
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7 January 2021
Brain and peripheral anandamide amidohydrolase and its inhibition by synthetic arachidonate analogues
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7 January 2021
Evidence that methyl arachidonyl fluorophosphonate is an irreversible cannabinoid receptor antagonist
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The effect of cannabidiol on mouse hepatic microsomal cytochrome P450-dependent anandamide metabolism
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7 January 2021
Lipoxygenase-catalyzed oxygenation of arachidonylethanolamide, a cannabinoid receptor agonist
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7 January 2021
Anandamide hydroxylation by brain lipoxygenase:metabolite structures and potencies at the cannabinoid receptor
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Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2.
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7 January 2021
Synthesis and cannabinoid receptor binding activity of conjugated triene anandamide, a novel eicosanoid
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The effect of hydroxylation of linoleoyl amides on their cannabinomimetic properties
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Brain cannabinoids in chocolate
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(R)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability
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Influence of cannabinoids on electrically evoked dopamine release and cyclic AMP generation in the rat striatum.
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The endogenous cannabinoid receptor ligand, anandamide, inhibits the motor behavior: role of nigrostriatal dopaminergic neurons
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delta 9-Tetrahydrocannabinol and anandamide enhance the ability of muscimol to induce catalepsy in the globus pallidus of rats
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Effects of cannabinoid receptor stimulation and blockade on catalepsy produced by dopamine receptor antagonists
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7 January 2021
The endogenous cannabinoid receptor agonist anandamide impairs memory in rats
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7 January 2021
The effects of anandamide on memory consolidation in mice involve both D1and D2 dopamine receptors
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7 January 2021
Improvement of memory in rodents by the selective CB1 cannabinoid receptor antagonist, SR 141716.
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7 January 2021
Inhibition of long-term potentiation in rat hippocampal slices by anandamide and WIN55212-2: reversal by SR141716 A, a selective antagonist of CB1 cannabinoid receptors
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7 January 2021
Long-term synaptic transformation of hippocampal CA1 gamma-aminobutyric acid synapses and the effect of anandamide
1 reference
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7 January 2021
Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures
1 reference
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7 January 2021
Effect of the brain constituent anandamide, a cannabinoid receptor agonist, on the hypothalamo-pituitary-adrenal axis in the rat.
1 reference
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7 January 2021
Effects of anandamide (endogen cannabinoid) on anterior pituitary hormone secretion in adult ovariectomized rats
1 reference
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reference URL
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7 January 2021
Time course of the effects of different cannabimimetics on prolactin and gonadotrophin secretion: evidence for the presence of CB1 receptors in hypothalamic structures and their involvement in the effects of cannabimimetics
1 reference
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7 January 2021
Arachidonyl ethanolamide (anandamide) activates the parvocellular part of hypothalamic paraventricular nucleus
1 reference
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reference URL
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7 January 2021
Arousal-enhancing properties of the CB1 cannabinoid receptor antagonist SR 141716A in rats as assessed by electroencephalographic spectral and sleep-waking cycle analysis
1 reference
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7 January 2021
Hypoactivity of the spinal cannabinoid system results in NMDA-dependent hyperalgesia.
1 reference
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7 January 2021
Further evidence for the presence of cannabinoid CB1 receptors in guinea-pig small intestine
1 reference
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reference URL
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7 January 2021
Evidence for the presence of cannabinoid CB1 receptors in mouse urinary bladder
1 reference
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7 January 2021
Further evidence for the presence of cannabinoid CB1 receptors in mouse vas deferens
1 reference
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7 January 2021
Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide
1 reference
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7 January 2021
Mechanism of the hypotensive action of anandamide in anesthetized rats
1 reference
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7 January 2021
Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves
1 reference
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Crossref
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7 January 2021
Endothelium-derived hyperpolarizing factor(s): updating the unknown
1 reference
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7 January 2021
An endogenous cannabinoid as an endothelium-derived vasorelaxant
1 reference
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Crossref
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7 January 2021
Comparative pharmacology of endothelium-derived hyperpolarizing factor and anandamide in rat isolated mesentery
1 reference
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Crossref
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7 January 2021
Evidence that anandamide and EDHF act via different mechanisms in rat isolated mesenteric arteries.
1 reference
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Crossref
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7 January 2021
Ophthalmic arachidonylethanolamide decreases intraocular pressure in normotensive rabbits
1 reference
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Crossref
reference URL
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7 January 2021
Ocular activity of topically administered anandamide in the rabbit
1 reference
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Crossref
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7 January 2021
N-(2-hydroxyethyl)hexadecanamide is orally active in reducing edema formation and inflammatory hyperalgesia by down-modulating mast cell activation
1 reference
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Crossref
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7 January 2021
Influence of fatty acid ethanolamides and delta9-tetrahydrocannabinol on cytokine and arachidonate release by mononuclear cells
1 reference
stated in
Crossref
reference URL
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7 January 2021
Anadamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis
1 reference
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Crossref
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7 January 2021
The peripheral cannabinoid receptor: adenylate cyclase inhibition and G protein coupling
1 reference
stated in
Crossref
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7 January 2021
Anandamide inhibits macrophage-mediated killing of tumor necrosis factor-sensitive cells
1 reference
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Crossref
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7 January 2021
Anandamide suppresses nitric oxide and TNF-alpha responses to Theiler's virus or endotoxin in astrocytes
1 reference
stated in
Crossref
reference URL
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7 January 2021
Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock
1 reference
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7 January 2021
Evidence for a cannabinoid receptor in sea urchin sperm and its role in blockade of the acrosome reaction
1 reference
stated in
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reference URL
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7 January 2021
Anandamide (arachidonylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction
1 reference
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Crossref
reference URL
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7 January 2021
Cannabinoid ligand-receptor signaling in the mouse uterus
1 reference
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Crossref
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7 January 2021
The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling
1 reference
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7 January 2021
Developmental aspects of anandamide: ontogeny of response and prenatal exposure
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Crossref
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7 January 2021
Atypical location of cannabinoid receptors in white matter areas during rat brain development
1 reference
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Crossref
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7 January 2021
Bioactive long chain N-acylethanolamines in five species of edible bivalve molluscs. Possible implications for mollusc physiology and sea food industry
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reference URL
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7 January 2021
The sleep-inducing lipid oleamide deconvolutes gap junction communication and calcium wave transmission in glial cells
1 reference
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Crossref
reference URL
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7 January 2021
Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys
1 reference
stated in
Crossref
reference URL
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7 January 2021
Arachidonylethanolamide (anandamide) binds with low affinity to dihydropyridine binding sites in brain membranes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900042-3
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7 January 2021
A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery.
1 reference
stated in
Crossref
reference URL
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7 January 2021
Studies on the effects of anandamide in rat hepatic artery
1 reference
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Crossref
reference URL
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7 January 2021
Detection of an endogenous cannabimimetic molecule, 2-arachidonoylglycerol, and cannabinoid CB1 receptor mRNA in human vascular cells: is 2-arachidonoylglycerol a possible vasomodulator?
1 reference
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Crossref
reference URL
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7 January 2021
Effects of topical alpha-substituted anandamides on intraocular pressure in normotensive rabbits
1 reference
stated in
Crossref
reference URL
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7 January 2021
Biphasic effects of anandamide
1 reference
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Crossref
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7 January 2021
Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors
1 reference
stated in
Crossref
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7 January 2021
Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Liquid chromatographic-atmospheric pressure chemical ionization mass spectrometric determination of anandamide and its analogs in rat brain and peripheral tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900042-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900042-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of glutamate-induced formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cultured neocortical neurons
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0005-2760(98)00042-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9630590
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9630590%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
PubMed publication ID
9630590
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9630590
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9630590%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
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